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Autor:
Christopher A. Beaudoin, Emmanouela Petsolari, Samir W. Hamaia, Sharif Hala, Fadwa S. Alofi, Arun P. Pandurangan, Tom L. Blundell, Sundeep Chaitanya Vedithi, Christopher L.-H. Huang, Antony P. Jackson
Publikováno v:
Biochemical and Biophysical Research Communications. 666:61-67
The RGD motif on the SARS-CoV-2 spike protein has been suggested to interact with RGD-binding integrins αVβ3 and α5β1 to enhance viral cell entry and alter downstream signaling cascades. The D405N mutation on the Omicron subvariant spike proteins
Publikováno v:
Biochemical and Biophysical Research Communications. 638:103-111
Skin is the biggest organ of the human body, which easily gets irritated by exposure to the sun. Skin photoaging and acute photodamage are caused by intense UV-B radiation. Therefore, it is imperative to find new compounds to prevent skin damage and
Publikováno v:
Biochemical and Biophysical Research Communications. 637:161-169
The influence of son of sevenless homolog 1 (SOS1) on invasion and metastasis of hepatocellular carcinoma (HCC) cells was investigated. HCC cells were transfected with siRNA and lentivirus to achieve SOS1 knock down/overexpression and changes in RNA
Autor:
Chikako Shibata, Motoyuki Otsuka, Takahiro Seimiya, Kazunaga Ishigaki, Yu Miyakawa, Takahiro Kishikawa, Mitsuhiro Fujishiro
Publikováno v:
Biochemical and Biophysical Research Communications. 637:314-321
Extracellular vesicles (EVs) released from cells into the blood facilitate intercellular communication and serve as new biomarkers to understand the pathophysiology of several conditions. Although the importance of the cargo inside EVs has been exten
Autor:
Zijie Wu, Lihua Ma, Peichun Lin, Zhenqing Dai, Zifan Lu, Linhong Yan, Chunxia Zhou, Zhong-Ji Qian, Pengzhi Hong, Chengyong Li
Publikováno v:
Biochemical and Biophysical Research Communications. 634:10-19
Extracellular vesicles (EVs) and their exosome subsets are vesicle-like nanoparticles (EVs) that are secreted by cells and contain various factors that treat various diseases. However, studies on extracting EVs from marine shellfish are still relativ
Publikováno v:
Biochemical and Biophysical Research Communications. 634:62-69
Static cold storage (SCS) is currently the most widely used method for organ preservation, but a number of limitations are associated including tissue damage and restricted opportunity for organ repair. Thus, the development of improved hypothermic s
Publikováno v:
Biochemical and Biophysical Research Communications. 636:113-118
Despite tremendous advances in the diagnosis and treatment of NSCLC, the morbidity and mortality of NSCLC still rank high worldwide. Epithelial-mesenchymal transition (EMT) is vital to the invasion, metastasis, and recurrence of NSCLC. Unfortunately,
Publikováno v:
Biochemical and Biophysical Research Communications. 636:190-196
PUF60 (Poly (U) binding splicing factor 60 kDa), a nucleic acid-binding protein, has been shown to regulate transcription and links to tumorigenesis in various cancers. However, its biological role and function in glioblastoma remain unknown. In this
Publikováno v:
Biochemical and Biophysical Research Communications. 636:75-83
During hypertension-induced endothelial dysfunction, periodic mechanical stretching (MS) activates related inflammatory pathways and leads to endothelial damage, but the underlying mechanisms remain unknown. The present study aimed to determine the i
Publikováno v:
Biochemical and Biophysical Research Communications. 634:168-174
Classical histological methods such as hematoxylin-eosin staining, have been, and in some areas still are, an important benchmark for the evaluation of biological tissues. However, the current method of assessment is primarily a qualitative assessmen