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Autor:
Mitsuo Tanabe, Takashi Iwai, Jun-Ichiro Oka, Akiyoshi Saitoh, Eri Koga, Junpei Takahashi, Daisuke Yamada, Yudai Ueta
Publikováno v:
Biochemical and Biophysical Research Communications. 528:174-178
Aim Oxytocin, a peptide hormone synthesized in the hypothalamic paraventricular nucleus, has been reported to participate in the regulation of learning and memory performance. However, no report has demonstrated the effect of oxytocin on the amyloid-
Autor:
Chunju Yang, Jin Bai, Guangzhi Zeng, Zhaoxiang Bian, Min Zhuang, Qi Lai, Yanhua Ma, Baomin Fan, Chengyuan Lin
Publikováno v:
Biochemical and Biophysical Research Communications. 525:326-333
Spexin (SPX) acts as a neuropeptide with pleiotropic functions that can participate in anxiety regulation. Corticotropin releasing factor (CRF) is widely expressed in brain tissues and associated with depression and anxiety and addiction. With the an
Autor:
Sung Ho Jin, Kwang Kon Kim, Jae Young Seong, Dasol Kang, Bora Jeong, Han Rae Kim, Dong Hee Kim, Byung Ju Lee, Jeong Woo Park
Publikováno v:
Biochemical and Biophysical Research Communications. 523:829-834
The cytokine-like protein FAM19A5 is highly expressed in the brain, but little is known about its functions there. Here, we found that FAM19A5 was expressed in mouse hypothalamic cells expressing proopiomelanocortin (POMC) and neuropeptide Y (NPY)/ag
Publikováno v:
Bioscience Reports
Tumor microenvironment (TME) plays a particularly important role in the progression, invasion and metastasis of cervical carcinoma (CC). Tumor-associated macrophages (TAMs) are significant components of the tumor microenvironment in CC. However, the
Publikováno v:
Biochem Biophys Res Commun
Estrogen therapy is used to treat patients with post-menopausal symptoms, such as hot flashes and dyspareunia. Estrogen therapy also decreases the risk of fractures from osteoporosis in post-menopausal women. However, estrogen increases the risk of v
Autor:
Yoshiaki Idemoto, Yoshino Matsuo, Shin-ichiro Miura, Takashi Kuwano, Yasunori Suematsu, Ken Kitajima
Publikováno v:
Biochemical and Biophysical Research Communications. 514:791-797
Blockers of G-protein coupled receptors (GPCRs), angiotensin II (Ang II) type 1 (AT1) receptor and β1-adrenergic (Ad) receptor, have been shown to improve the prognosis of cardiovascular disease. Cholesterol molecules in the cell membrane are needed
Publikováno v:
Biochemical and Biophysical Research Communications. 505:229-235
Leptin-mediated DNA-binding activity of STAT3 in hypothalamus plays crucial roles in the maintenance of energy homeostasis in lean mice; however its effects still remains unclear in case of leptin resistance in mice with diet induced obesity (DIO). I
Publikováno v:
Analytical biochemistry. 626
Examination of cerebrospinal fluid in atypical bacterial meningitis (ABM) is similar to that of viral encephalitis (VE), so ABM can easily be misdiagnosed as VE, which can delay diagnosis and treatment. We developed a simple, rapid hand-held lateral
Autor:
Satoru Funamoto, Alam Shahnur, Hina Uchiyama, Tomohiro Miyasaka, Masaki Nakano, Masaki Nishimura, Yuuna Shirai, Takaomi C. Saido, Mohammad Moniruzzaman, Takashi Saito, Nobuto Kakuda, Seiko Ishihara
Publikováno v:
Biochemical and biophysical research communications. 535
Amyloid-β (Aβ) is the major component of senile plaques in Alzheimer’s disease (AD) brains. Senile plaques are generally observed in cerebral cortex (CTX) rather than cerebellum (CBL) in AD patients. However, it is not clear why CBL has less Aβ
Autor:
I. Shimomura, Kiyoshi Fukui, Sho Yoneda, H. Sho, Shuichi Toyoda, Junji Kozawa, Yukari Fujita, Hidetoshi Eguchi, Hitoshi Ozawa, Chisaki Ishibashi
Publikováno v:
Biochemical and biophysical research communications. 534
There have been several clinical reports of transient postoperative hyperglycemia in patients with insulinoma, but the effect of insulinoma on normal β-cells has not been investigated. We examined the glucose transporter 2 (GLUT2) and glucagon-like