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Autor:
Damian Ryszawy, Zuzanna Setkowicz, Joanna Chwiej, Maciej Pudełek, Marta Gajewska, Natalia Janik-Olchawa, Magdalena Wytrwal-Sarna, Maciej Sniegocki, Agnieszka Drozdz, Karolina Planeta
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Although the key factor affecting the biocompatibility of IONPs is the core size, there is a lack of regular investigation concerning the impact of the parameter on the toxicity of these nanomaterials. Therefore, such studies were carried out in this
Autor:
Kuniko Katagiri, Miku Ishizawa, Mari Kannagi, Yoshiko Nagano, Nobuyo Kondo, Atsuhiko Hasegawa, Takeru Yoneda, Takao Masuda
Publikováno v:
Biochemical and Biophysical Research Communications. 574:104-109
Immunomodulatory imide drugs (IMiDs), such as lenalidomide and pomalidomide, exert pleiotropic effects, e.g., antitumor effects in multiple myeloma, by binding the protein Cereblon and altering its substrate specificity. Lenalidomide is approved for
Publikováno v:
Biochemical and Biophysical Research Communications. 551:161-167
Physiological oxygen concentration (physioxia) ranges from 1 to 8% in human tissues while many researchers cultivate mammalian cells under an atmospheric concentration of 21% (hyperoxia). Oxygen is one of the significant gases which functions in huma
Publikováno v:
Biochemical and Biophysical Research Communications. 534:672-679
Aldosterone is synthesized in the adrenal by the aldosterone synthase CYP11B2. Although the control of CYP11B2 expression is important to maintain the mineral homeostasis, its overexpression induced by the depolarization-induced calcium (Ca2+) signal
Publikováno v:
Biochemical and Biophysical Research Communications. 533:613-619
c-Myc modulator 1 (MM1), also known as PFDN5, is the fifth subunit of prefoldin. It was previously reported that MM1-based prefoldin promotes folding of actin during assembly of cytoskeleton, which plays key roles in cell migration. However, no evide
Publikováno v:
Biochemical and Biophysical Research Communications
The pandemic of COVID-19 is spreading unchecked due to the lack of effective antiviral measures. Silver nanoparticles (AgNP) have been studied to possess antiviral properties and are presumed to inhibit SARS-CoV-2. Due to the need for an effective ag
Autor:
Kayo Kiyoi, Yoshikazu Haramoto, Tomoko Watanabe, Sayoko Saito, Shuuji Mawaribuchi, Hiroaki Tateno, Keiko Hiemori
Publikováno v:
Biochemical and Biophysical Research Communications. 529:575-581
Quality control for human induced pluripotent stem cells (hiPSCs) is important for efficient and stable production of hiPSC-derived cell therapy products to be used for transplantation. During cell culture, hiPSCs spontaneously undergo morphological
Publikováno v:
Biochemical and Biophysical Research Communications. 527:915-921
The migration and invasion of trophoblasts during early pregnancy in known to play an important role in placental development, which ensures the oxygen and nutrients to the fetus. Accumulating evidences suggest that Delta-Like 4(DLL4)-Notch signaling
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Tumor invasion within the interstitial space is critically regulated by the force balance between cell-extracellular matrix (ECM) and cell-cell interactions. Interstitial flows (IFs) are present in both healthy and diseased tissues. However, the role
Autor:
Yihua Wu, Huina Zhang, Zhong Xincao, Han Wu, Juan Ye, Dajing Xia, Hongyi Li, Xin Shi, Jinlong Tang
Publikováno v:
FEBS Letters. 594:1207-1217
MicroRNAs (miRNAs) are involved in the post-transcriptional regulation of mRNAs. However, the function of miRNAs is unclear in epithelial-mesenchymal transition (EMT) of pterygium, a disease characterized by abnormal fibrovascular proliferation and i