Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Zhu, Meng"'
Autor:
Zeng, Fei, Fan, Yan, Brown, Russell W., Drew Gill, Wesley, Price, Jennifer B., Jones, Thomas C., Zhu, Meng-Yang
Publikováno v:
ETSU Faculty Works.
This study investigated the effects of the pharmacological manipulation of noradrenergic activities on dopaminergic phenotypes in aged rats. Results showed that the administration of L-threo-3,4-dihydroxyphenylserine (L-DOPS) for 21 days significantl
Externí odkaz:
https://dc.etsu.edu/etsu-works-2/552
Autor:
Cui, Kui, Yang, Fan, Tufan, Turan, Raza, Muhammad U., Zhan, Yanqiang, Fan, Yan, Zeng, Fei, Brown, Russell W., Price, Jennifer B., Jones, Thomas C., Miller, Gary W., Zhu, Meng Y.
Publikováno v:
ETSU Faculty Works.
Dysfunction of the central noradrenergic and dopaminergic systems is the primary neurobiological characteristic of Parkinson’s disease (PD). Importantly, neuronal loss in the locus coeruleus (LC) that occurs in early stages of PD may accelerate pro
Publikováno v:
ETSU Faculty Works.
Glucocorticoids affect cellular and molecular events in brains by modulating the expression of many genes during stress. In the present study, we examined the regulatory effect of corticosterone on the expression and function of the norepinephrine tr
Externí odkaz:
https://dc.etsu.edu/etsu-works/16716
Autor:
Zhang, Yi, Li, Hui, Li, Yi, Sun, Xiuli, Zhu, Meng-Yang, Hanley, Gregory, LeSage, Gene, Yin, Deling
Publikováno v:
ETSU Faculty Works.
Opioids are powerful pain relievers, but also potent inducers of dependence and tolerance. Chronic morphine administration (via subcutaneous pellet) induces morphine dependence in the nucleus accumbens, an important dependence region in the brain, ye
Externí odkaz:
https://dc.etsu.edu/etsu-works/16434
Publikováno v:
ETSU Faculty Works.
It is documented that stress activates the locus coeruleus-norepinephrine system. However, there are far few reports regarding effects of stress on the expression of dopamine β-hydroxylase, a hallmark enzyme of the noradrenergic neuron. In the prese
Externí odkaz:
https://dc.etsu.edu/etsu-works/14259
Publikováno v:
ETSU Faculty Works.
Stress has been reported to activate the locus coeruleus (LC)-noradrenergic system. However, the molecular link between chronic stress and noradrenergic neurons remains to be elucidated. In the present study adult Fischer 344 rats were subjected to a
Externí odkaz:
https://dc.etsu.edu/etsu-works/16075
Publikováno v:
ETSU Faculty Works.
Chronic stress and dysfunction of the serotonergic system in the brain have been considered two of the major risks for development of depression. In this study, adult Fischer 344 rats were subjected to a regimen of chronic social defeat (CSD). To mim
Externí odkaz:
https://dc.etsu.edu/etsu-works/16022
Publikováno v:
ETSU Faculty Works.
Dopamine β-hydroxylase (DBH) and norepinephrine (NE) transporter (NET) are the noradrenergic phenotypes for their functional importance to noradrenergic neurons. It is known that in vivo N-(2-chloroethyl)-N-ethyl-2- bromobenzylamine (DSP4) treatment
Externí odkaz:
https://dc.etsu.edu/etsu-works/15724
Publikováno v:
ETSU Faculty Works.
Degeneration of the noradrenergic neurons has been reported in the brain of patients suffering from neurodegenerative diseases. However, their pathological characteristics during the neurodegenerative course and underlying mechanisms remain to be elu
Externí odkaz:
https://dc.etsu.edu/etsu-works/15434
Publikováno v:
ETSU Faculty Works.
DNA damage is a form of cell stress and injury. Increased systemic DNA damage is related to the pathogenic development of neurodegenerative diseases. Depression occurs in a relatively high percentage of patients suffering from degenerative diseases,
Externí odkaz:
https://dc.etsu.edu/etsu-works/15408