Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kiseok Jang"'
Publikováno v:
Journal of Clinical Pathology. 74:111-115
AimsCD47 is upregulated on the surface of various tumour cells, and it is known to inhibit the phagocytosis of tumour cells by macrophages. Immunotherapy that targets CD47 has demonstrated success in preclinical trials and is now under clinical inves
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 8, p e0236896 (2020)
PLoS ONE, Vol 15, Iss 8, p e0236896 (2020)
Single-stranded DNA binding protein 2 (SSBP2) is ubiquitously expressed, with several studies reporting it to be a tumor suppressor. We investigated SSBP2 expression and its clinicopathological significance in gastric cancer. SSBP2 expression was exa
Autor:
Jongmin Sim, Seongsik Bang, Yeseul Kim, Su Jin Shin, Kiseok Jang, Hyungsung Kim, Seongun Park, Seungyun Jee
Publikováno v:
In vivo (Athens, Greece). 34(1)
Background/aim Microtubule-associated scaffold protein 1 (MTUS1) acts as tumor suppressor in several cancer types. This study assessed the relationship between clinicopathological characteristics and expression of microRNA candidates based on MTUS1 e
Autor:
Kiseok Jang, Su Jin Shin, Yesul Kim, Rehman Abdul, Dong-Hoon Kim, Hyein Ahn, Seung Sam Paik, Hyunsung Kim, Dongho Choi, Jongmin Sim
Publikováno v:
American Journal of Clinical Pathology. 149:117-127
Objectives Recent research has demonstrated that forkhead box O3a (FoxO3a) may function as an oncogenic transcription factor. We sought to validate the clinicopathologic significance of FoxO3a expression in hepatocellular carcinoma (HCC). Methods Wes
Autor:
Seung Sam Paik, Hosub Park, Hyunsung Kim, Seungyun Jee, Seongeon Park, Yeseul Kim, Seongsik Bang, Kiseok Jang
Publikováno v:
Indian Journal of Pathology and Microbiology, Vol 64, Iss 5, Pp 78-84 (2021)
Background: Yin Yang 1 (YY1), the multifunctional transcription factor, has recently been assigned biological properties related to human malignancies. YY1 can facilitate both tumor suppression and tumor growth. The conflicting role of YY1 in human m
Autor:
Hyein Ahn, Yeseul Kim, Abdul Rehman, Su Jin Shin, Jongmin Sim, Hyunsung Kim, Kiseok Jang, Min Sung Chung
Publikováno v:
Journal of clinical pathology. 71(9)
AimsForkhead box O (FOXO) transcription factors, consisting of FOXO1, FOXO3a, FOXO4 and FOXO6, are involved in carcinogenesis and tumour progression. Recent studies have suggested that FOXOs act as tumour suppressors in a variety of human cancers. Th
Autor:
Jong Kyu Woo, Jin Woo Choi, Dong-Hui Shin, Ji-Hye Park, Hye-Yeon Kim, Seung Hyun Oh, Sehwan Kim, Hyung-Yong Kim, Kiseok Jang, Taekwon Son, Hee-Young Won, Gu Kong, Young Ha Oh, Hee Joo Choi, Kijong Yi, Jeong-Yeon Lee, Ju-Hee Kang
Publikováno v:
Journal of Clinical Investigation. 125:1801-1814
The polycomb protein MEL-18 has been proposed as a tumor suppressor in breast cancer; however, its functional relevance to the hormonal regulation of breast cancer remains unknown. Here, we demonstrated that MEL-18 loss contributes to the hormone-ind
Autor:
Hyein Ahn, Kiseok Jang, Jongmin Sim, Min Sung Chung, Seung Sam Paik, Se Jin Jang, Hulin Han, Rehman Abdul
Publikováno v:
Translational Research. 163:242-251
MicroRNAs (miRNAs) are 19∼22 nucleotide-long, noncoding, small RNAs, involved in post-transcriptional regulation of many target genes. The miRNA-200 family has been shown to play a crucial role in the epithelial to mesenchymal transition in human c
Publikováno v:
Medicine
Supplemental Digital Content is available in the text
The cell-surface glycoprotein, mesothelin, is normally present on mesothelial cells. Overexpression of mesothelin has been reported in many tumors and is correlated with poor outcome. We inve
The cell-surface glycoprotein, mesothelin, is normally present on mesothelial cells. Overexpression of mesothelin has been reported in many tumors and is correlated with poor outcome. We inve
Autor:
Se Min Jang, Seung Sam Paik, Young Jin Jun, Kang Hong Lee, Jongmin Sim, Kiseok Jang, Kyueng-Whan Min, Hye In Ahn, Si-Hyong Jang, Hulin Han
Publikováno v:
Journal of Clinical Pathology. 65:902-906
Cell adhesion molecule 4 (CADM4) is a novel tumour suppressor. The purpose of this study was to investigate the correlation between its expression and the expression of E-cadherin and Ki-67 in colorectal adenocarcinomas, as well as its effect on pati