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Autor:
Natálie Klubíčková, Michael Michal, Abbas Agaimy, Nina Zidar, Michal Pavlovský, Kenji Yorita, Petr Grossmann, Veronika Hájková, Nikola Ptáková, Petr Šteiner, Michal Michal
Publikováno v:
Virchows Archiv. 481:721-729
We report 7 cases of an indolent, variably myxoid tumor of the vocal cords, characterized by overt cellular atypia with large cells containing intranuclear and intracytoplasmic vacuoles, delicate curvilinear vessels, and sparse inflammatory infiltrat
Autor:
Jia-hao Bao, Jiang-bo Li, Han-sen Lin, Wen-jin Zhang, Bing-yan Guo, Jun-jie Li, Liang-min Fu, Yang-peng Sun
Publikováno v:
Analytical Cellular Pathology. 2022:1-27
Clear cell renal cell carcinoma (ccRCC) is the most common histological and devastating subtype of renal cell carcinoma. Necroptosis is a form of programmed cell death that causes prominent inflammatory responses. miRNAs play a significant role in ca
Publikováno v:
Virchows Archiv. 481:511-516
We report a case of primary rectal neoplasm with a novel DDX5-TFEB fusion in a 14-year-old boy. Histologically, the neoplasm was composed of epithelioid tumor cells with abundant clear to eosinophilic cytoplasm, arranged in nests with rich stromal ca
Autor:
Hongseok Yun, Seung Hong Choi, Ka Young Lim, Seung-Ki Kim, Yumi Shim, Tae Min Kim, Jin-Woo Park, Hyunhee Kim, Jeongwan Kang, Sung Hye Park, Chul-Kee Park, Kwanghoon Lee, Jae Kyung Won
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
Mismatch repair-deficient (MMRD) brain tumors are rare among primary brain tumors and can be induced by germline or sporadic mutations. Here, we report 13 MMRD-associated (9 sporadic and 4 Lynch syndrome) primary brain tumors to determine clinicopath
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
Gliomas are the most common and recalcitrant intracranial tumors, approximately a quarter of which are classified as lower-grade gliomas (WHO II–III). Although the prognosis of lower-grade gliomas (LGGs) is significantly better than that of higher-
Autor:
María Soledad Rodríguez Duque, Juan Rodríguez Cobo, Eduardo Ibaseta Fidalgo, Carmen Vallejo Secadas, Julia Medina Del Valle, Javier Gómez Román, Javier Freire Salinas, Marta María Mayorga Fernández, Servando Lazuén Fernández, Javier Álvarez Gama
Publikováno v:
Romanian Journal of Morphology and Embryology
Introduction Mammary analogue secretory carcinoma (MASC) is a recent discovered entity of salivary glands tumors, reported for first time in 2010. The presence of a translocation encodes the ETS variant transcription factor 6-neurotrophic tyrosine re
Autor:
Liliana-Ana Tuţă, Antonela Anca Nicolau, Mariana Aşchie, Mariana Deacu, Gabriela Izabela Bălţătescu, Anca Florentina Mitroi, Mădălina Boşoteanu, Lucian Cristian Petcu, Oana Cojocaru, Manuela Enciu
Publikováno v:
Romanian Journal of Morphology and Embryology
Breast cancer (BC) is the second most frequent type of cancer for both sexes combined, after lung cancer. Triple-negative BC (TNBC) molecular subtype is characterized by lack of estrogen receptor (ER), progesterone receptor (PR) and human epidermal g
Publikováno v:
Virchows Archiv
Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine malignancy of the skin. The cell of origin of MCC is thus far unknown and proposed cells of origin include Merkel cells, pro-/pre- or pre-B cells, epithelial stem cells, and dermal s
Autor:
Claudio Ghimenton, Giampietro Pinna, Michele Simbolo, Francesco Sala, Matteo Brunelli, Serena Ammendola, Maria L. Piredda, Valeria Barresi, Nicolò Caldonazzi, Aldo Scarpa, Pietro Luigi Poliani
Publikováno v:
Virchows Archiv
Oligodendroglioma is defined by IDH mutation and 1p/19q codeletion. The latter is mutually exclusive to ATRX immunohistochemical loss and has been recently associated with the loss of H3K27me3 immunostaining. We aimed to assess the diagnostic and pro
Autor:
Maria Luisa Carcangiu, Lisa Licitra, Paolo Bossi, Siranoush Manoukian, Carla B. Ripamonti, Mara Colombo, Andrea Vingiani, Paolo Radice, Laura D. Locati
Publikováno v:
Virchows Archiv. 479:221-226
Salivary gland cancers (SGCs) are rare malignancies with highly heterogeneous histological features. Patients affected with SGCs are at increased risk of secondary malignancies, including breast cancer (BC). Previous studies enlightened a possible li