Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Tobias Pischon"'
Autor:
Tobias Pischon, Carola G. Schipke, Georg Winterer, Oliver Peters, Insa Feinkohl, Jochen Kruppa, Felix Menne
Publikováno v:
Journal of Alzheimer's Disease
Background Collection of cerebrospinal fluid (CSF) for measurement of amyloid-β (Aβ) species is a gold standard in Alzheimer's disease (AD) diagnosis, but has risks. Thus, establishing a low-risk blood Aβ test with high AD sensitivity and specific
Autor:
Anna Floegel, Wolfgang Otto, Heiner Boeing, Tobias Pischon, Cornelia Weikert, Thomas Illig, Ulrike Rolle-Kampczyk, Jerzy Adamski, Tilman Kühn, Disorn Sookthai, Theron Johnson, Martin von Bergen, Cornelia Prehn, Rudolf Kaaks
Publikováno v:
European Journal of Epidemiology
European journal of epidemiology, 33(1): 55-66
Floegel, A, Kuhn, T, Sookthai, D, Johnson, T, Prehn, C, Rolle-Kampczyk, U, Otto, W, Weikert, C, Illig, T, von Bergen, M, Adamski, J, Boeing, H, Kaaks, R & Pischon, T 2018, ' Serum metabolites and risk of myocardial infarction and ischemic stroke: a targeted metabolomic approach in two German prospective cohorts ', European Journal of Epidemiology, vol. 33, no. 1, pp. 55-66 . https://doi.org/10.1007/s10654-017-0333-0
Floegel, A, Kühn, T, Sookthai, D, Johnson, T, Prehn, C, Rolle-Kampczyk, U, Otto, W, Weikert, C, Illig, T, von Bergen, M, Adamski, J, Boeing, H, Kaaks, R & Pischon, T 2018, ' Serum metabolites and risk of myocardial infarction and ischemic stroke : a targeted metabolomic approach in two German prospective cohorts ', European Journal of Epidemiology, vol. 33, no. 1, pp. 55-66 . https://doi.org/10.1007/s10654-017-0333-0
Eur. J. Epidemiol. 33, 55–66 (2018)
European journal of epidemiology, 33(1): 55-66
Floegel, A, Kuhn, T, Sookthai, D, Johnson, T, Prehn, C, Rolle-Kampczyk, U, Otto, W, Weikert, C, Illig, T, von Bergen, M, Adamski, J, Boeing, H, Kaaks, R & Pischon, T 2018, ' Serum metabolites and risk of myocardial infarction and ischemic stroke: a targeted metabolomic approach in two German prospective cohorts ', European Journal of Epidemiology, vol. 33, no. 1, pp. 55-66 . https://doi.org/10.1007/s10654-017-0333-0
Floegel, A, Kühn, T, Sookthai, D, Johnson, T, Prehn, C, Rolle-Kampczyk, U, Otto, W, Weikert, C, Illig, T, von Bergen, M, Adamski, J, Boeing, H, Kaaks, R & Pischon, T 2018, ' Serum metabolites and risk of myocardial infarction and ischemic stroke : a targeted metabolomic approach in two German prospective cohorts ', European Journal of Epidemiology, vol. 33, no. 1, pp. 55-66 . https://doi.org/10.1007/s10654-017-0333-0
Eur. J. Epidemiol. 33, 55–66 (2018)
Metabolomic approaches in prospective cohorts may offer a unique snapshot into early metabolic perturbations that are associated with a higher risk of cardiovascular diseases (CVD) in healthy people. We investigated the association of 105 serum metab
Publikováno v:
Metabolism: clinical and experimental. 92
The global epidemic of obesity is a major public health problem today. Obesity increases the risk of many chronic diseases, such as type 2 diabetes, coronary heart disease, and certain types of cancer, and is associated with lower life expectancy. Th
Autor:
Cornelia Weikert, Anna Floegel, Jerzy Adamski, Cornelia Prehn, Stefan Dietrich, H. Boeing, Dagmar Drogan, Tobias Pischon
Publikováno v:
Hypertension. 68:471-477
Metabolomics is a promising tool to gain new insights into early metabolic alterations preceding the development of hypertension in humans. We therefore aimed to identify metabolites associated with incident hypertension using measured data of serum
Autor:
Tobias Pischon, Marc J. Gunter, Anne Tjønneland, Kay-Tee Khaw, Heiner Boeing, Bas Bueno-de-Mesquita, Amalia Mattiello, Isabelle Romieu, Agnetha Linn Rostgaard-Hansen, Elio Riboli, Pagona Lagiou, Sabrina Schlesinger, Heinz Freisling, Kathryn E. Bradbury, Krasimira Aleksandrova, Rudolf Kaaks, Claudia Agnoli, Kim Overvad, Mazda Jenab, Veronika Fedirko, Christina C. Dahm, Christina Bamia, Antonia Trichopoulou
Publikováno v:
Aleksandrova, K, Schlesinger, S, Fedirko, V, Jenab, M, Bueno-de-Mesquita, B, Freisling, H, Romieu, I, Pischon, T, Kaaks, R, Gunter, M J, Dahm, C C, Overvad, K, Rostgaard-Hansen, A L, Tjønneland, A, Trichopoulou, A, Bamia, C, Lagiou, P, Agnoli, C, Mattiello, A, Bradbury, K, Khaw, K-T, Riboli, E & Boeing, H 2017, ' Metabolic Mediators of the Association Between Adult Weight Gain and Colorectal Cancer : Data From the European Prospective Investigation into Cancer and Nutrition (EPIC) Cohort ', American Journal of Epidemiology, vol. 185, no. 9, pp. 751-764 . https://doi.org/10.1093/aje/kww194
Evidence indicates that gaining weight in adult life is associated with an elevated risk of colorectal cancer; however, biological mechanisms that may explain this association remain unclear. We evaluated the mediation effect of 20 different biomarke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3eace30d371e78f78f33a85c6a2ffc1
http://hdl.handle.net/10029/621219
http://hdl.handle.net/10029/621219
Autor:
Catalina Bonet, Antonia Trichopoulou, Dagmar Drogan, Tilman Kühn, Elisabete Weiderpass, Dagfinn Aune, Pagona Lagiou, Elio Riboli, Kim Overvad, Rosario Tumino, Kay-Tee Khaw, Miren Dorronsoro, María José Sánchez, A. M. May, Marion Carayol, Elissavet Valanou, Christina C. Dahm, Kristin Benjaminsen Borch, Christina Bamia, Marie Christine Bouton-Ruault, Krasimira Aleksandrova, Tobias Pischon, Patrik Wennberg, Aurelio Barricarte, Rudolf Kaaks, Heather Ward, Sunday Oluwafemi Oyeyemi, Nada Assi, Eleni Peppa, Domenico Palli, Bethany Van Guelpen, Mazda Jenab, Anne Tjønneland, Jonna K. van Vulpen, Timothy J. Key, Sabina Rinaldi, Heiner Boeing, Paula Jakszyn, Heinz Freisling, Carmen Navarro, Salvatore Panico, Carlo La Vecchia, J. Ramón Quirós, Claudia Agnoli, Nicholas J. Wareham, Bas Bueno-de-Mesquita, Carlotta Sacerdote, Michael F. Leitzmann
Publikováno v:
Aleksandrova, K, Jenab, M, Leitzmann, M, Bueno-de-Mesquita, B, Kaaks, R, Trichopoulou, A, Bamia, C, Lagiou, P, Rinaldi, S, Freisling, H, Carayol, M, Pischon, T, Drogan, D, Weiderpass, E, Jakszyn, P, Overvad, K, Dahm, C C, Tjønneland, A, Bouton-Ruault, M-C, Kühn, T, Peppa, E, Valanou, E, La Vecchia, C, Palli, D, Panico, S, Sacerdote, C, Agnoli, C, Tumino, R, May, A, van Vulpen, J, Benjaminsen Borch, K, Oluwafemi Oyeyemi, S, Quirós, J R, Bonet, C, Sánchez, M-J, Dorronsoro, M, Navarro, C, Barricarte, A, van Guelpen, B, Wennberg, P, Key, T J, Khaw, K-T, Wareham, N, Assi, N, Ward, H A, Aune, D, Riboli, E & Boeing, H 2017, ' Physical activity, mediating factors and risk of colon cancer : insights into adiposity and circulating biomarkers from the EPIC cohort ', International Journal of Epidemiology, vol. 46, no. 6, pp. 1823-1835 . https://doi.org/10.1093/ije/dyx174
International Journal of Epidemiology, 46(6), 1823. Oxford University Press
International Journal of Epidemiology, 46(6), 1823. Oxford University Press
Background: There is convincing evidence that high physical activity lowers the risk of colon cancer; however, the underlying biological mechanisms remain largely unknown. We aimed to determine the extent to which body fatness and biomarkers of vario
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170b31d1eec727fd212fab800fe37d25
https://pure.au.dk/portal/da/publications/physical-activity-mediating-factors-and-risk-of-colon-cancer(39d41eb9-78b9-45fd-9f6b-f4f644f82de4).html
https://pure.au.dk/portal/da/publications/physical-activity-mediating-factors-and-risk-of-colon-cancer(39d41eb9-78b9-45fd-9f6b-f4f644f82de4).html
Autor:
Diana van Heemst, Matthias B. Schulze, Joris Deelen, Jerzy Adamski, Ramneek Gupta, Sophie Molnos, P. Eline Slagboom, Valborg Gudmundsdottir, Simone Wahl, Annette Peters, Ewan R. Pearson, Anette-G. Ziegler, Anna Floegel, Harald Grallert, E. Marelise W. Eekhoff, A.M.C. Simonis-Bik, Christian Herder, Helle Krogh Pedersen, René Pool, Eco J. C. de Geus, Mark Haid, Gonneke Willemsen, Nienke van Leeuwen, Dorret I. Boomsma, Karsten Suhre, Michael Roden, Tobias Pischon, Daniela Much, Leen M 't Hart, Christian Gieger, Marian Beekman, Wolfgang Rathmann, Mark H. H. Kramer, Cornelia Prehn, Anna Jonsson, Wolfgang Bernigau, Harmen H.M. Draisma, Sandra Hummel, Barbara Thorand, Mark I. McCarthy, Michaela Breier, Heiner Boeing, Rui Wang-Sattler, Søren Brunak
Publikováno v:
Molnos, S, Wahl, S, Haid, M, Eekhoff, E M W, Pool, R, Floegel, A, Deelen, J, Much, D, Prehn, C, Breier, M, Draisma, H H, van Leeuwen, N, Simonis-Bik, A M C, Jonsson, A, Willemsen, G, Bernigau, W, Wang-Sattler, R, Suhre, K, Peters, A, Thorand, B, Herder, C, Rathmann, W, Roden, M, Gieger, C, Kramer, M H H, van Heemst, D, Pedersen, H K, Gudmundsdottir, V, Schulze, M B, Pischon, T, de Geus, E J C, Boeing, H, Boomsma, D I, Ziegler, A G, Slagboom, P E, Hummel, S, Beekman, M, Grallert, H, Brunak, S, McCarthy, M I, Gupta, R, Pearson, E R, Adamski, J & 't Hart, L M 2018, ' Metabolite ratios as potential biomarkers for type 2 diabetes : a DIRECT study ', Diabetologia, vol. 61, no. 1, pp. 117-129 . https://doi.org/10.1007/s00125-017-4436-7
Diabetologia, 61(1), 117-129. Springer Verlag
Diabetologia, 61(1), 117-129
Molnos, S, Wahl, S, Haid, M, Eekhoff, E M W, Pool, R, Floegel, A, Deelen, J, Much, D, Prehn, C, Breier, M, Draisma, H H, van Leeuwen, N, Simonis-Bik, A M C, Jonsson, A E, Willemsen, G, Bernigau, W, Wang-Sattler, R, Suhre, K, Peters, A, Thorand, B, Herder, C, Rathmann, W, Roden, M, Gieger, C, Kramer, M H H, van Heemst, D, Pedersen, H K, Gudmundsdottir, V, Schulze, M B, Pischon, T, de Geus, E J C, Boeing, H, Boomsma, D I, Ziegler, A G, Slagboom, P E, Hummel, S, Beekman, M, Grallert, H, Brunak, S, McCarthy, M I, Gupta, R, Pearson, E R, Adamski, J & 'T Hart, L M 2018, ' Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study ', Diabetologia, vol. 61, pp. 117-129 . https://doi.org/10.1007/s00125-017-4436-7
Molnos, S, Wahl, S, Haid, M, Eekhoff, E M W, Pool, R, Floegel, A, Deelen, J, Much, D, Prehn, C, Breier, M, Draisma, H H, van Leeuwen, N, Simonis-Bik, A M C, Jonsson, A, Willemsen, G, Bernigau, W, Wang-Sattler, R, Suhre, K, Peters, A, Thorand, B, Herder, C, Rathmann, W, Roden, M, Gieger, C, Kramer, M H H, van Heemst, D, Pedersen, H K, Gudmundsdottir, V, Schulze, M B, Pischon, T, de Geus, E J C, Boeing, H, Boomsma, D I, Ziegler, A G, Slagboom, P E, Hummel, S, Beekman, M, Grallert, H, Brunak, S, McCarthy, M I, Gupta, R, Pearson, E R, Adamski, J & 't Hart, L M 2017, ' Metabolite ratios as potential biomarkers for type 2 diabetes : a DIRECT study ', Diabetologia . https://doi.org/10.1007/s00125-017-4436-7
Diabetologia
Diabetologia, 61(1):117-129
Molnos, S, Wahl, S, Haid, M, Eekhoff, E M W, Pool, R, Floegel, A, Deelen, J, Much, D, Prehn, C, Breier, M, Draisma, H H, van Leeuwen, N, Simonis-Bik, A M C, Jonsson, A, Willemsen, G, Bernigau, W, Wang-Sattler, R, Suhre, K, Peters, A, Thorand, B, Herder, C, Rathmann, W, Roden, M, Gieger, C, Kramer, M H H, van Heemst, D, Pedersen, H K, Gudmundsdottir, V, Schulze, M B, Pischon, T, de Geus, E J C, Boeing, H, Boomsma, D I, Ziegler, A G, Slagboom, P E, Hummel, S, Beekman, M, Grallert, H, Brunak, S, McCarthy, M I, Gupta, R, Pearson, E R, Adamski, J & ’T Hart, L M 2018, ' Metabolite ratios as potential biomarkers for type 2 diabetes : a DIRECT study ', Diabetologia, vol. 61, no. 1, pp. 117-129 . https://doi.org/10.1007/s00125-017-4436-7
Diabetologia, 61(1), 117-129. Springer Verlag
Diabetologia, 61(1), 117-129
Molnos, S, Wahl, S, Haid, M, Eekhoff, E M W, Pool, R, Floegel, A, Deelen, J, Much, D, Prehn, C, Breier, M, Draisma, H H, van Leeuwen, N, Simonis-Bik, A M C, Jonsson, A E, Willemsen, G, Bernigau, W, Wang-Sattler, R, Suhre, K, Peters, A, Thorand, B, Herder, C, Rathmann, W, Roden, M, Gieger, C, Kramer, M H H, van Heemst, D, Pedersen, H K, Gudmundsdottir, V, Schulze, M B, Pischon, T, de Geus, E J C, Boeing, H, Boomsma, D I, Ziegler, A G, Slagboom, P E, Hummel, S, Beekman, M, Grallert, H, Brunak, S, McCarthy, M I, Gupta, R, Pearson, E R, Adamski, J & 'T Hart, L M 2018, ' Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study ', Diabetologia, vol. 61, pp. 117-129 . https://doi.org/10.1007/s00125-017-4436-7
Molnos, S, Wahl, S, Haid, M, Eekhoff, E M W, Pool, R, Floegel, A, Deelen, J, Much, D, Prehn, C, Breier, M, Draisma, H H, van Leeuwen, N, Simonis-Bik, A M C, Jonsson, A, Willemsen, G, Bernigau, W, Wang-Sattler, R, Suhre, K, Peters, A, Thorand, B, Herder, C, Rathmann, W, Roden, M, Gieger, C, Kramer, M H H, van Heemst, D, Pedersen, H K, Gudmundsdottir, V, Schulze, M B, Pischon, T, de Geus, E J C, Boeing, H, Boomsma, D I, Ziegler, A G, Slagboom, P E, Hummel, S, Beekman, M, Grallert, H, Brunak, S, McCarthy, M I, Gupta, R, Pearson, E R, Adamski, J & 't Hart, L M 2017, ' Metabolite ratios as potential biomarkers for type 2 diabetes : a DIRECT study ', Diabetologia . https://doi.org/10.1007/s00125-017-4436-7
Diabetologia
Diabetologia, 61(1):117-129
Molnos, S, Wahl, S, Haid, M, Eekhoff, E M W, Pool, R, Floegel, A, Deelen, J, Much, D, Prehn, C, Breier, M, Draisma, H H, van Leeuwen, N, Simonis-Bik, A M C, Jonsson, A, Willemsen, G, Bernigau, W, Wang-Sattler, R, Suhre, K, Peters, A, Thorand, B, Herder, C, Rathmann, W, Roden, M, Gieger, C, Kramer, M H H, van Heemst, D, Pedersen, H K, Gudmundsdottir, V, Schulze, M B, Pischon, T, de Geus, E J C, Boeing, H, Boomsma, D I, Ziegler, A G, Slagboom, P E, Hummel, S, Beekman, M, Grallert, H, Brunak, S, McCarthy, M I, Gupta, R, Pearson, E R, Adamski, J & ’T Hart, L M 2018, ' Metabolite ratios as potential biomarkers for type 2 diabetes : a DIRECT study ', Diabetologia, vol. 61, no. 1, pp. 117-129 . https://doi.org/10.1007/s00125-017-4436-7
Aims/hypothesis Circulating metabolites have been shown to reflect metabolic changes during the development of type 2 diabetes. In this study we examined the association of metabolite levels and pairwise metabolite ratios with insulin responses after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3138b1b57ae911b25528c3590b8b87bd
https://doi.org/10.1007/s00125-017-4436-7
https://doi.org/10.1007/s00125-017-4436-7
Publikováno v:
Clinical chemistry. 64(1)
BACKGROUNDThe worldwide rise of obesity has provoked intensified research to better understand its pathophysiology as a means for disease prevention. Several biomarkers that may reflect various pathophysiological pathways that link obesity and cardio
Autor:
Jerzy Adamski, Tobias Pischon, Dagmar Drogan, Matthias B. Schulze, Angelika Wientzek, Anna Floegel, Ursula Bachlechner, Simone Jacobs, H. Boeing, Cornelia Prehn, Jan Krumsiek
Publikováno v:
Int. J. Obes. 38, 1388-1396 (2014)
International Journal of Obesity (2005)
International Journal of Obesity (2005)
Background/Objective It is not yet resolved how lifestyle factors and intermediate phenotypes interrelate with metabolic pathways. We aimed to investigate the associations between diet, physical activity, cardiorespiratory fitness and obesity with se
Autor:
Karsten Suhre, Tobias Pischon, Rui Wang-Sattler, Barbara Thorand, Marjolein Haftenberger, Anna Floegel, Jerzy Adamski, Harald Grallert, Ursula Bachlechner, Simone Wahl, Annette Peters, Benedikt Merz, Anja Schienkiewitz, Heiner Boeing, Ute Nöthlings
Publikováno v:
PLoS ONE 11:e0157733 (2016)
PLOS ONE, 11(6): e0157733
PLoS ONE, Vol 11, Iss 6, p e0157733 (2016)
PLoS ONE
PLOS ONE, 11(6): e0157733
PLoS ONE, Vol 11, Iss 6, p e0157733 (2016)
PLoS ONE
OBJECTIVE: Our study aims to identify metabolic markers associated with either a gain in abdominal (measured by waist circumference) or peripheral (measured by hip circumference) body fat mass. METHODS: Data of 4 126 weight-gaining adults (18-75 year
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d76cd5489201b3fc114ebcaa3a2b254
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=48842
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=48842