Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Yong J. Lee"'
Autor:
Yong Seok Park, Kalishwaralal Kalimuthu, Yong J. Lee, Ja Lok Ku, Jin Hong Kim, Xu Luo, Lin Zhang, M. Haroon A. Choudry
Publikováno v:
Journal of Cellular Physiology. 236:6666-6677
Abnormalities of the tumor vasculature result in insufficient blood supply and development of a tumor microenvironment that is characterized by low glucose concentrations, low extracellular pH, and low oxygen tensions. We previously reported that glu
Autor:
Yong J. Lee, Ki Sa Sung, William T. Kwon, Zong Sheng Guo, Dae Hee Lee, David L. Bartlett, Yong Tae Kwon, Sang Cheul Oh
Publikováno v:
Journal of Cellular Biochemistry. 117:1078-1091
It is well known that tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis can be initially triggered by surface death receptors (the extrinsic pathway) and subsequently amplified through mitochondrial dysfunction (the in
Autor:
Ashok K. Dilly, Yong J. Lee, Yong Tae Kwon, David L. Bartlett, Haroon A. Choudry, Xinxin Song
Publikováno v:
Molecular Cancer Research. 13:1533-1543
Colorectal peritoneal carcinomatosis (CPC) exhibits severe tumor hypoxia, leading to drug resistance and disease aggressiveness. This study demonstrates that the combination of the chemotherapeutic agent mitomycin C with the proteasome inhibitor bort
Autor:
Yong Tae Kwon, Dae Hee Lee, David L. Bartlett, Yoshiro Saito, Xinxin Song, Daeho Kim, Bo Yeon Kim, Sang Mi Shim, Jung Lim Kim, Sung Tae Kim, Sang Cheul Oh, Zong Sheng Guo, Ah Jung Heo, Soyeon Jeong, Yong J. Lee, Junho Lee
Publikováno v:
Autophagy. 14(11)
Macroautophagy is induced under various stresses to remove cytotoxic materials, including misfolded proteins and their aggregates. These protein cargoes are collected by specific autophagic receptors such as SQSTM1/p62 (sequestosome 1) and delivered
Publikováno v:
Molecular cancer research : MCR. 16(7)
Since its discovery in 2012, ferroptosis has been well characterized by the accumulation of lipid peroxides due to the failure of glutathione-dependent antioxidant defenses. It is known as an iron-dependent form of programmed cell death, which is dis
Autor:
Herbert J. Zeh, Yong J. Lee, Haroon A. Choudry, Brendon D. Honick, Z S Guo, David L. Bartlett, Ashok K. Dilly
Publikováno v:
Oncotarget
// Ashok K. Dilly 1 , Brendon D. Honick 1 , Yong J. Lee 1, 2 , Zong S. Guo 1 , Herbert J. Zeh 1 , David L. Bartlett 1 and Haroon A. Choudry 1 1 Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh PA 15232, USA 2 Department of P
Autor:
Yong J. Lee, Dae Hee Lee, Haroon A. Choudry, Min Jee Jo, David L. Bartlett, Young Sun Lee, William T. Kwon, Yoon A. Jeong, Se Hoon Hong
Publikováno v:
Oncotarget
Ferroptosis is a type of programmed cell death that depends on iron and is characterized by the accumulation of lipid peroxides. In the present study, we investigated the nature of the interplay between ferroptosis and other forms of cell death such
Publikováno v:
Molecular Cancer Research. 10:1567-1579
Colorectal cancer is the third leading cause of cancer-related mortality in the world. The main cause of death because of colorectal cancer is hepatic metastases, which can be treated using isolated hepatic perfusion (IHP), allowing treatment of colo
Publikováno v:
Food and Chemical Toxicology. 49:271-280
Astaxanthin (AST) is a powerful antioxidant that occurs naturally in a wide variety of living organisms. We have investigated the role of AST in preventing 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced apoptosis of the substantia nigra
Autor:
Dae Hee Lee, Yong J. Lee, Se Hoon Hong, Yoo A. Jeong, Min J. Jo, Young Sun Lee, David L. Bartlett, William T. Kwon, Haroon A. Choudry
Publikováno v:
Cancer Research. 78:2321-2321
Ferroptosis is a type of programmed cell death that depends on iron and is characterized by the accumulation of lipid peroxides. In the present study, we investigated the nature of the interplay between ferroptosis and other forms of cell death such