Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Yedy Israel"'
Autor:
Fernando Ezquer, Yedy Israel, María Elena Quintanilla, Paola Morales, Mario Herrera-Marschitz, Marcelo Ezquer
Publikováno v:
Alcoholism: Clinical and Experimental Research. 42:1988-1999
Background Life expectancy is greatly reduced in individuals presenting alcohol use disorders and chronic smoking. Literature studies suggest that common mechanisms may apply to the chronic use and relapse of both alcohol and nicotine. It is hypothes
Publikováno v:
Alcohol and Alcoholism. 52:i4-i30
Autor:
Marcelo Ezquer, Mario Herrera-Marschitz, Fernando Ezquer, Eduardo Karahanian, Paola Morales, María Elena Quintanilla, Yedy Israel, Mario Rivera-Meza
Publikováno v:
Frontiers in Behavioral Neuroscience
This review addresses the biological factors that influence (i) the acquisition of alcohol intake, (ii) the maintenance of chronic alcohol intake and (iii) alcohol relapse-like drinking behavior in animals bred for their high-ethanol intake. Data fro
Autor:
María Elena Quintanilla, Eduardo Karahanian, Yedy Israel, Lutske Tampier, Mario Herrera-Marschitz, Mario Rivera-Meza
Publikováno v:
Addiction Biology. 20:336-344
Previous studies suggest that acetaldehyde generated from ethanol in the brain is reinforcing. The present studies tested the feasibility of achieving a long-term reduction of chronic and post-deprivation binge ethanol drinking by a single administra
Autor:
Yedy Israel, María Elena Quintanilla, Lutske Tampier, Mario Herrera-Marschitz, Mario Rivera-Meza, Eduardo Karahanian
Publikováno v:
Alcoholism: Clinical and Experimental Research. 36:517-522
Background: In animal models of continuous alcohol self-administration, in which physicaldependence does not constitute the major factor of ethanol intake, 2 factors likely contribute tothe perpetuation of alcohol self-administration: (i) the rewardi
Autor:
Mario Herrera-Marschitz, Victor Gonzalez-Lira, Yedy Israel, Lutske Tampier, María Elena Quintanilla, Mario Rivera-Meza, Diego Bustamante, Eduardo Karahanian, Paola Morales
Publikováno v:
Alcoholism: Clinical and Experimental Research. 35:606-612
Backround While the molecular entity responsible for the rewarding effects of virtually all drugs of abuse is known; that for ethanol remains uncertain. Some lines of evidence suggest that the rewarding effects of alcohol are mediated not by ethanol
Publikováno v:
Alcoholism: Clinical and Experimental Research. 35:806-810
This account of recent work presented at the 4th International Symposium on Alcohol Pancreatitis and Cirrhosis reports animal studies aimed at determining the role of the "acetaldehyde burst," generated shortly upon ethanol intake, as the mechanism o
Publikováno v:
Alcoholism: Clinical and Experimental Research. 34:976-987
Alcohol use disorders (abuse and dependence, AUD) are multifactorial phenomena, depending on the interplay of environmental and genetic variables. This review describes current developments in animal research that may help (a) develop gene therapies
Publikováno v:
ALCOHOLISM, CLINICAL AND EXPERIMENTAL RESEARCH
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Disulfiram, an inhibitor of aldehyde dehydrogenase used in the treatment of alcoholism, is an effective medication when its intake is supervised by a third person. However, its therapeutic efficacy varies widely, in part due to the fact that disulfir
Autor:
Lutske Tampier, Eduardo Karahanian, Amalia Sapag, Paula Ocaranza, Yedy Israel, María Elena Quintanilla
Publikováno v:
Alcoholism: Clinical and Experimental Research. 32:52-57
Background: Some gene polymorphisms strongly protect against the development of alcoholism. A large proportion of East Asians carry a protective inactivating mutation in aldehyde dehydrogenase (ALDH2*2). These subjects display high levels of blood ac