Zobrazeno 1 - 10
of 443
pro vyhledávání: '"Wulf, A."'
Autor:
Julia Thomson, Thomas Mika, Verena Nilius-Eliliwi, Susanne Klein-Scory, Gerald Wulf, Roland Schroers, Alexander Baraniskin, Deepak Vangala
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss, Pp 539-550 (2021)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Chimeric antigen receptor (CAR)-T cells are increasingly used for the treatment of hematologic malignancies. Treatment success relies highly upon sufficient expansion of CAR-T effector cells. Accordingly, longitudinal quantification of CAR-T cells du
Autor:
Wolfgang Walther, Annika Wulf-Goldenberg, Ulrike Stein, Johannes Merk, Iduna Fichtner, Keziban M. Alp, Giannino Patone, Tamara Kanashova, Christine Sers, Philipp Mertins, Maria Rivera, Jens Hoffmann
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 1, Pp 21-35 (2021)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 1, Pp 21-35 (2021)
Patient-derived xenograft (PDX) tumor models represent a valuable platform for identifying new biomarkers and novel targets, to evaluate therapy response and resistance mechanisms. This study aimed at establishment, characterization and therapy testi
Publikováno v:
Heerfordt, I M, Fontenete, S, Lerche, C M & Wulf, H C 2022, ' Distribution of protoporphyrin IX in erythrocytes in a case of acquired erythropoietic protoporphyria ', Photodiagnosis and Photodynamic Therapy, vol. 37, 102629 . https://doi.org/10.1016/j.pdpdt.2021.102629
Background Erythropoietic protoporphyria (EPP) is a rare genetic photodermatosis caused by loss-of-function mutations in the gene for ferrochelatase leading to accumulation of the fluorescent protoporphyrin IX (PpIX) in erythrocytes. The mutations ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc91e0eaf04766f1eb59791ef7ea6493
https://curis.ku.dk/portal/da/publications/distribution-of-protoporphyrin-ix-in-erythrocytes-in-a-case-of-acquired-erythropoietic-protoporphyria(0f8cfe6e-d4ea-4143-b541-686ec6a911fc).html
https://curis.ku.dk/portal/da/publications/distribution-of-protoporphyrin-ix-in-erythrocytes-in-a-case-of-acquired-erythropoietic-protoporphyria(0f8cfe6e-d4ea-4143-b541-686ec6a911fc).html
Publikováno v:
Stroke
Background and Purpose— Ischemic stroke impairs endoplasmic reticulum (ER) function, causes ER stress, and activates the unfolded protein response. The unfolded protein response consists of 3 branches controlled by ER stress sensor proteins, which
Publikováno v:
Acta Crystallographica. Section D, Structural Biology
The crystal structure of the c-type cytochrome NirC from Pseudomonas aeruginosa has been determined and reveals the simultaneous presence of monomers and 3D domain-swapped dimers in the same asymmetric unit.
Monoheme c-type cytochromes are impor
Monoheme c-type cytochromes are impor
Autor:
Gerburg M. Wulf, Lin Ding, Hai Hu, Phei Er Saw, Jiewen Chen, Man-Li Luo, Yandan Yao, Herui Yao, Huangming Hong, Xiaorong Lin, Wenkui Fu, Zhuofei Bi, Tao Qin, Qingjian Li, Xiao-Ding Xu, Fang Zheng, Wei Wu, Erwei Song
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
Nature Communications
Resistance development to one chemotherapeutic reagent leads frequently to acquired tolerance to other compounds, limiting the therapeutic options for cancer treatment. Herein, we find that overexpression of Rac1 is associated with multi-drug resista
Autor:
Nicole M. Nichols, Maguire Sean, Nan Dai, Paul Humbert, Madalee G. Wulf, Yanxia Bei, Shengxi Guan, Ivan R. Corrêa
Publikováno v:
The Journal of Biological Chemistry
Single-cell RNA-Seq (scRNA-Seq) has led to an unprecedented understanding of gene expression and regulation in individual cells. Many scRNA-Seq approaches rely upon the template switching property of Moloney murine leukemia virus (MMLV)-type reverse
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 11718, p 11718 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 11718, p 11718 (2021)
Neuroblastoma is a common extracranial solid tumour of childhood, responsible for 15% of cancer-related deaths in children. Prognoses vary from spontaneous remission to aggressive disease with extensive metastases, where treatment is challenging. Tum
Autor:
Andres Jäschke, Franziska Billau, Luisa Welp, Alexander Wulf, Julia Grawenhoff, Maik Schauerte, Katharina Höfer, Henning Urlaub
The mechanisms by which viruses hijack their host’s genetic machinery are of enormous current interest. One mechanism is adenosine diphosphate (ADP) ribosylation, where ADP-ribosyltransferases (ARTs) transfer an ADP-ribose fragment from the ubiquit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29bf7dda30f73e87ed24400bf40b4da1
https://doi.org/10.21203/rs.3.rs-590309/v1
https://doi.org/10.21203/rs.3.rs-590309/v1
Autor:
Steven J. Isakoff, Gerburg M. Wulf, William T. Barry, Hao Guo, Erin R. Macrae, Heather A. Parsons, Ian E. Krop, Tianyu Li, Nabihah Tayob
Publikováno v:
JCO Precis Oncol
PURPOSE Human epidermal growth factor receptor 2 (HER2)–directed treatments improve outcomes for patients with HER2-positive metastatic breast cancer (MBC). Current identification of patients with HER2-positive disease relies on tumor tissue testin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f08f6145d614bdfb64880ccb6db8aae
https://europepmc.org/articles/PMC9848583/
https://europepmc.org/articles/PMC9848583/