Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Wei, Qin"'
Publikováno v:
Laboratory Investigation. 101:865-877
Myocardial ischemia/reperfusion injury (MIRI) causes severe damage in cardiac tissue, thereby resulting in a high rate of mortality. 6-Gingerol (6-G) is reported to play an essential role in alleviating MIRI. However, the underlying mechanism remains
Autor:
Jian Wang, Ling-Xin Meng, Yuntao Zhang, Qiang Ren, Huijie Gao, Chao Liu, Hui-yun Wang, Li-tao Zhang, Caiju Zhou, Wei Qin
Publikováno v:
Aging (Albany NY)
Desmoplasia in the extracellular matrix (ECM) is one of the hallmarks of pancreatic cancer (PC), a virtually incurable disease. Decorin, a classical small leucine-rich proteoglycan found in the ECM, was upregulated in PC tissue samples according to t
Autor:
Aihong Zhou, Ying Li, Wei Qin, Fangyu Li, Yiping Wei, Jianping Jia, Carlos Cruchaga, Xiumei Zuo, Bruno A. Benitez, Qi Wang, Hongmei Jin, Longfei Jia
Publikováno v:
Human Molecular Genetics
To identify novel risk genes and better understand the molecular pathway underlying Alzheimer’s disease (AD), whole-exome sequencing was performed in 215 early-onset AD (EOAD) patients and 255 unrelated healthy controls of Han Chinese ethnicity. Su
Autor:
Yuanxing Chen, Nannan Chu, Zhenzhong Qian, Linling Que, Wei Qin, Kai Huang, Qing He, Ying Ding, Jisheng Zhang
Publikováno v:
Journal of Pharmacy and Pharmacology. 73:388-397
Objectives To determine the kinetics of the formation of 10,11-dihydro-10-hydroxy-carbazepine (MHD)-O-glucuronide in human liver microsomes (HLMs), human intestine microsomes (HIMs), human kidney microsomes (HKMs) and recombinant human UDP-glucuronos
Autor:
Lu Xing, Huan Zhou, Qi Sheng Wang, Chun Xia He, Fang Zhou, Feng Yu, Wei Qin, Peng Quan Li, Jianhua He, Xin Zhou, Xi Jin, Hui Ling Cao, Ping Li, Dong Zhao, Hui Jin Li
Publikováno v:
Acta Crystallographica Section D Structural Biology. 77:86-97
Debio0932 is a promising lead compound in phase I clinical trials targeting the N-terminal ATP-binding pocket of the molecular chaperone heat-shock protein 90 (Hsp90N). The absence of a crystal structure of the Hsp90N–Debio0932 complex, however, ha
Publikováno v:
Fish & Shellfish Immunology. 107:9-15
Tiger frog virus (TFV) belongs to the genus Ranavirus (family Iridoviridae) and causes significant harm in cultured frogs, resulting in substantial losses in ecological and economic field in Southern China. Attachment is the first step in viral life
Autor:
Longfei Jia, Fangyu Li, Cuibai Wei, Min Zhu, Qiumin Qu, Wei Qin, Yi Tang, Luxi Shen, Yanjiang Wang, Lu Shen, Honglei Li, Dantao Peng, Lan Tan, Benyan Luo, Qihao Guo, Muni Tang, Yifeng Du, Jiewen Zhang, Junjian Zhang, Jihui Lyu, Ying Li, Aihong Zhou, Fen Wang, Changbiao Chu, Haiqing Song, Liyong Wu, Xiumei Zuo, Yue Han, Junhua Liang, Qi Wang, Hongmei Jin, Wei Wang, Yang Lü, Fang Li, Yuying Zhou, Wei Zhang, Zhengluan Liao, Qiongqiong Qiu, Yan Li, Chaojun Kong, Haishan Jiao, Jie Lu, Jianping Jia
Publikováno v:
Brain
Previous genome-wide association studies have identified dozens of susceptibility loci for sporadic Alzheimer’s disease, but few of these loci have been validated in longitudinal cohorts. Establishing predictive models of Alzheimer’s disease base
Publikováno v:
Clinical Interventions in Aging. 15:171-175
Anti-γ-aminobutyric acid B receptor (anti-GABABR) encephalitis is a rare type of autoimmune encephalitis (AE). Although it responds well to immunomodulating therapy and has favorable prognosis, anti-GABABR AE has often been misdiagnosed as infectiou
Autor:
Wei Qin, Yong Zhang, Huan Yang, Zhange Li, Xin Liu, Longyin Zhang, Yue Zhang, Haiying Zhang, Xiaohui Chen, Dan Xiao, Chaoqian Xu, Baofeng Yang
Publikováno v:
International Journal of Cardiology. 295:7-13
Background Vascular aging has profound effects on cardiovascular diseases. Endothelial to mesenchymal transition (EndMT) is defined as the acquisition of mesenchymal characteristics by endothelial cells (ECs) and has been found induced in a model of
Autor:
Yun Zhao, Manman Lu, Xianxian Lu, Jiting Zhang, Jiawei Huang, Qian Zhang, Haiyan Cui, Zhuge Xi, Rui Li, Wei Qin
Publikováno v:
Environmental Pollution. 252:1519-1531
Some basic research has shown that nanomaterials can aggravate allergic asthma. However, its potential mechanism is insufficient. Based on the research that alumina nanopowder (nAl2O3) has been reported to cause lung tissue damage, the purpose of thi