Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Wayne B. Anderson"'
Autor:
Danièle Evain-Brion, Patrice Thérond, Pascale Gerbaud, Wayne B. Anderson, Françoise Raynaud, Loïc Petzold
Publikováno v:
Journal of Autoimmunity. 24:69-78
Superoxide dismutases' (SODs) expression is altered in several diseases including Alzheimer, atherosclerosis, cancer and psoriasis. Previously, we reported a marked increase in Mn-SOD and Cu,Zn-SOD functional activity in human dermal psoriatic fibrob
Publikováno v:
Chemical Research in Toxicology. 17:650-662
Dichloroacetic acid (DCA) is a drinking water contaminant, a therapeutic agent, and a rodent carcinogen. Glutathione transferase zeta (GSTZ1-1) catalyzes the biotransformation of a range of α-haloalkanoates and the cis−trans isomerization of maley
Autor:
Patrice Thérond, Danièle Evain-Brion, Jean Guibourdenche, Wayne B. Anderson, Stéphanie Dimon-Gadal, Françoise Raynaud, Pascale Gerbaud
Publikováno v:
Journal of Investigative Dermatology. 114:984-989
Differences in oxidative damage, as measured by an increase in the carbonylation of macromolecules, were determined in situ with skin biopsies from psoriatic patients and controls. High levels of carbonyl residues were consistently detected in the de
Publikováno v:
Oncogene. 15:53-61
Raf-1 protein serine/threonine kinase has been implicated in growth and damage-responsive signal transduction pathways. Several reports indicate an important role of Ras protein in the growth factor-induced activation of Raf-1. Here we investigated t
Autor:
Yuko Kawakami, Koichiro Ozawa, Csaba Lehel, Hiromi Fukamachi, Wayne B. Anderson, Libo Yao, Toshiaki Kawakami, Hidefumi Suzuki, Jianbei Deng
Publikováno v:
Journal of Biological Chemistry. 272:13033-13039
Pleckstrin homology (PH) domains comprised of loosely conserved sequences of approximately 100 amino acid residues are a functional protein motif found in many signal-transducing and cytoskeletal proteins. We recently demonstrated that the PH domains
Autor:
Danièle Evain-Brion, Wayne B. Anderson, Isabelle Gorin, Denis Marciano, Pascale Gerbaud, Françoise Raynaud, Charis Liapi
Publikováno v:
Free Radical Biology and Medicine. 22:623-632
Previous studies have established that cyclic AMP-dependent protein kinase (PKA) activity, as well as 8-azido-[32P]-cAMP binding to the RI and RII regulatory subunits, are decreased in cells from psoriatic patients compared to cells from normal patie
Autor:
Françoise Raynaud, Pascale Gerbaud, Wayne B. Anderson, Stéphanie Dimon, Patrice Thérond, Danièle Evain-Brion
Publikováno v:
Journal of Investigative Dermatology. 106:1325-1331
Antioxidant enzyme activities in fibroblasts and erythrocytes prepared from normal and psoriatic patients were measured and compared. The most significant differences were noted in superoxide dismutase (SOD) activities. A dramatic (5.2-fold) increase
Publikováno v:
Archives of Biochemistry and Biophysics. 285:382-387
The oxidant mitogen/tumor promoter, periodate, was used to selectively modify either the regulatory domain or the catalytic domain of protein kinase C (PKC) to induce oxidative activation or inactivation of PKC, respectively. Periodate, at micromolar
Publikováno v:
The Journal of biological chemistry. 279(47)
Recently we reported that simultaneous treatment of NIH 3T3 cells with the combination of phorbol myristate acetate (PMA) and hydrogen peroxide (H2O2) resulted in synergistic activation of Raf-1 kinase (Lee, M., Petrovics, G., and Anderson, W. B. (20
Publikováno v:
Biochemical and biophysical research communications. 311(4)
We have previously demonstrated that a 33kDa C-terminal fragment of c-Raf-1 underwent a mobility shift in response to hydrogen peroxide (H(2)O(2)) and phorbol myristate acetate (PMA), respectively. In this study, we have demonstrated that H(2)O(2) in