Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Thomas S. Uldrick"'
Autor:
Amrit Singh, Anthony P. Schwarer, Helen L. Partridge, Frits van Rhee, Daniel J. Arenas, David C. Fajgenbaum, Katie L. Stone, Mariko Okumura, Jason R. Ruth, Nelson Hamerschlak, Michael R. Betts, Thomas S. Uldrick, Gerald Wertheim, Christopher S. Nabel, Taku Kambayashi, Michael B. Jordan, Sheila K Pierson, Fabio Freire José, Alberto Sada Japp, Arthur H. Rubenstein, Adam D. Cohen, Ruth-Anne Langan, Vera P. Krymskaya
Publikováno v:
Journal of Clinical Investigation. 129:4451-4463
BACKGROUND Idiopathic multicentric Castleman disease (iMCD) is a hematologic illness involving cytokine-induced lymphoproliferation, systemic inflammation, cytopenias, and life-threatening multi-organ dysfunction. The molecular underpinnings of inter
Publikováno v:
Curr HIV/AIDS Rep
PURPOSE OF REVIEW: Immune checkpoint inhibitors targeting the programmed cell death-1 (PD-1) pathway are a class of anti-cancer immunotherapy agents changing treatment paradigms of many cancers that occur at higher rates in people living with HIV (PL
Autor:
Lisa M. Miller Jenkins, Robert Yarchoan, Brandon F. Keele, Jennifer Jones, Thorsten Demberg, Thomas Musich, Marjorie Robert-Guroff, Thomas S. Uldrick
Flow cytometry is utilized extensively for cellular analysis, but technical limitations have prevented its routine application for characterizing virus. The recent introduction of nanoscale fluorescence-activated cytometric cell sorting now allows an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d5d445cfc5740710c4be261513f0427
https://europepmc.org/articles/PMC5313071/
https://europepmc.org/articles/PMC5313071/
Autor:
Thomas S. Uldrick, Drew Pratt
Publikováno v:
Blood. 127(23)
[Figure][1] A 59-year-old man was diagnosed with HIV and Kaposi sarcoma (KS) 8 years prior to death; CD4+ count at diagnosis was 538 cells per μL. Despite antiretroviral therapy, KS required several additional therapies. More than 7 years later, the
Autor:
Nazzarena Labo, Denise Whitby, Dominic Esposito, Thomas S. Uldrick, Rachel Bagni, Mark N. Polizzotto, Alexandra Turano, Wendell Miley, Kathleen M. Wyvill, Robert Yarchoan, Matthew Bess, Vickie Marshall, William K. Gillette
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 10, Iss 3, p e1004046 (2014)
PLoS Pathogens, Vol 10, Iss 3, p e1004046 (2014)
The Kaposi sarcoma associated herpesvirus (KSHV) genome encodes more than 85 open reading frames (ORFs). Serological evaluation of KSHV infection now generally relies on reactivity to just one latent and/or one lytic protein (commonly ORF73 and K8.1)
Autor:
Seth M. Steinberg, Mark N. Polizzotto, Richard F. Little, Thomas S. Uldrick, Vickie Marshall, Kathleen M. Wyvill, Robert Yarchoan, Deirdre O'Mahony, Karen Aleman, Denise Whitby, Stefania Pittaluga, Victoria Wang, Giovanna Tosato
Publikováno v:
Blood. 122(26)
Kaposi sarcoma herpesvirus (KSHV)-associated multicentric Castleman disease (MCD) is a polyclonal B-cell lymphoproliferative disorder. Human (h) IL-6 and a KSHV-encoded homolog, viral IL-6, have been hypothesized to contribute to its pathogenesis, bu
Autor:
Shuhei Sakakibara, Paola Gasperini, Thomas S. Uldrick, Georgina Espígol-Frigolé, Giovanna Tosato, Robert Yarchoan
Kaposi’s sarcoma-associated herpesvirus (KSHV) K13/vFLIP (viral Flice-inhibitory protein) induces transcription of numerous genes through NF-κB activation, including pro-inflammatory cytokines, which contribute to the pathogenesis of Kaposi’s sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81866129f717e8cefbc10761a1f036d
https://europepmc.org/articles/PMC3594048/
https://europepmc.org/articles/PMC3594048/
Autor:
Rolf Renne, Karen Aleman, Alex K. Ray, Thomas S. Uldrick, Octavio A. Quiñones, Denise Whitby, Robert M. Leighty, Richard F. Little, Soo-Jin Han, Nazzarena Labo, Kathy Wyvill, Eugene V. Barsov, David E. Ott, Mark N. Polizzotto, Vickie Marshall, Robert Yarchoan
Publikováno v:
Infectious Agents and Cancer, Vol 7, Iss Suppl 1, p O5 (2012)
Infectious Agents and Cancer
Infectious Agents and Cancer
Kaposi sarcoma-associated herpesvirus (KSHV) encodes 12 pre-microRNAs which potentially yield 25 mature microRNAs and have been shown to play prominent roles in the viral lifecycle including maintaining viral latency, evading the host immune response
Autor:
Denise Whitby, Richard F. Little, Robert Leighty, Nazzarena Labo, Robert Yarchoan, Vickie Marshall, Thomas S. Uldrick, Karen Aleman, Alex K. Ray, Kathy Wyvill, Mark N. Polizzotto
Publikováno v:
The Journal of infectious diseases. 205(11)
Kaposi sarcoma–associated herpesvirus (KSHV), also known as human herpesvirus 8, is the etiologic agent of Kaposi sarcoma (KS), primary effusion lymphoma (PEL), and a subtype of multicentric Castleman disease (MCD), most commonly seen in people wit
Publikováno v:
Frontiers in Microbiology, Vol 3 (2012)
Frontiers in Microbiology, Vol 8 (2017)
Frontiers in Microbiology
Frontiers in Microbiology, Vol 8 (2017)
Frontiers in Microbiology
Soon after the discovery of Kaposi sarcoma (KS)-associated herpesvirus (KSHV), it was appreciated that this virus was associated with most cases of multicentric Castleman disease (MCD) arising in patients infected with human immunodeficiency virus. I