Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ryo, Ito"'
Publikováno v:
Biochemical and Biophysical Research Communications. 534:672-679
Aldosterone is synthesized in the adrenal by the aldosterone synthase CYP11B2. Although the control of CYP11B2 expression is important to maintain the mineral homeostasis, its overexpression induced by the depolarization-induced calcium (Ca2+) signal
FABP7 Regulates Acetyl-CoA Metabolism Through the Interaction with ACLY in the Nucleus of Astrocytes
Autor:
Yuji Owada, Masayuki Kanamori, Kosuke Jozaki, Shuhei Kobayashi, Subrata Kumar Shil, Ryo Zama, Hiroshi Kogo, Ariful Islam, Kazuhiko Igarashi, Hirofumi Miyazaki, Chie Shimamoto-Mitsuyama, Yoshiteru Kagawa, Shin Ichiro Kanno, Banlanjo Abdulaziz Umaru, Shun Sato, Ryo Ito, Teiji Tominaga, Hiroki Shima, Akira Yasui, Kohji Fukunaga, Yui Yamamoto, Takeo Yoshikawa, Norihiro Sugino, Akira Sugawara
Publikováno v:
Molecular Neurobiology
Fatty acid binding protein 7 (FABP7) is an intracellular fatty acid chaperon that is highly expressed in astrocytes, oligodendrocyte-precursor cells, and malignant glioma. Previously, we reported that FABP7 regulates the response to extracellular sti
Autor:
Toshiya Tanaka, Aoi Uchida, Takeshi Inagaki, Shogo Yamamoto, Tatsuhiko Kodama, Yoshihiro Matsumura, Ryo Ito, Yohei Abe, Youichiro Wada, Ryo Nakaki, Hiroyuki Aburatani, Koichi Node, Shuichi Tsutsumi, Rei Yamaguchi, Makoto Arai, Hitomi Fujihashi, Hiroki Takahashi, Ji Zhang, Kenta Magoori, Hiroyuki Hirakawa, Takeshi Kawamura, Hiroshi Kimura, Shin Ichi Inoue, Juro Sakai, Chaoran Yang, Ayumu Yajima, Timothy F. Osborne, Ge Yang, Satoshi Ota, Takeshi Yoneshiro
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Nature Communications
Enhancer activation is essential for cell-type specific gene expression during cellular differentiation, however, how enhancers transition from a hypoacetylated “primed” state to a hyperacetylated-active state is incompletely understood. Here, we
Autor:
Hideki Hasegawa, Takato Odagiri, Hideki Asanuma, Krisna Nur Andriana Pangesti, Takeshi Kurata, Pretty Multihartina, Shin-ichi Tamura, Kyosuke Senchi, Vivi Setiawaty, Tadaki Suzuki, Elly van Riet, Ryo Ito, Masato Tashiro, Akira Ainai, Kazuyuki Ikeda
Publikováno v:
Microbiology and Immunology
Intranasally administered influenza vaccines could be more effective than injected vaccines, because intranasal vaccination can induce virus‐specific immunoglobulin A (IgA) antibodies in the upper respiratory tract, which is the initial site of inf
Autor:
Ginji Oomori, Kazuyuki Murase, Koji Miyanishi, Tadashi Hasegawa, Naotaka Hayasaka, Makoto Emori, Masayoshi Kobune, Tomoki Kikuchi, Ryo Ito, Kohichi Takada, Satoshi Iyama, Shintaro Sugita, Hiroshi Ikeda, Junji Kato
Publikováno v:
Thoracic Cancer
Thoracic Cancer, Vol 10, Iss 12, Pp 2312-2315 (2019)
Thoracic Cancer, Vol 10, Iss 12, Pp 2312-2315 (2019)
SMARCA4‐deficient thoracic sarcoma (SMARCA4‐DTS) is a new clinical entity characterized by SMARCA4 inactivation and has a dismal prognosis because of rapid growth. Effective treatments for SMARCA4‐DTS have not yet been developed. Most recently,
Autor:
Hiroki Shima, Ikuko Sato, Kazuhiko Igarashi, Koji Masuda, Akira Sugawara, Ryo Ito, Katsuhiko Shirahige, Hiroki Shimada, Atsushi Yokoyama
Publikováno v:
Endocrine journal. 68(4)
Angiotensin II (Ang II) is a well-known peptide that maintains the balance of electrolytes in the higher vertebrates. Ang II stimulation in the adrenal gland induces the synthesis of mineralocorticoids, mainly aldosterone, through the up-regulation o
Autor:
Taisuke Mochida, Noriko Tsubooka-Yamazoe, Hideyuki Hiyoshi, Hikaru Ueno, Hirokazu Matsumoto, Ryo Ito, Taro Toyoda
Publikováno v:
Diabetes. 69(4)
The host environment is a crucial factor for considering the transplant of stem cell–derived immature pancreatic cells in patients with type 1 diabetes. Here, we investigated the effect of insulin (INS)-deficient diabetes on the fate of immature pa
Relationship of the quaternary structure of human secretory IgA to neutralization of influenza virus
Autor:
Takato Odagiri, Shin-ichi Tamura, Hideki Hasegawa, Akira Ainai, Tadaki Suzuki, Krisna Nur Andriana Pangesti, Akira Kawaguchi, Pretty Multihartina, Ryo Ito, Vivi Setiawaty, Masato Tashiro
Publikováno v:
Proceedings of the National Academy of Sciences. 112:7809-7814
Secretory IgA (S-IgA) antibodies, the major contributors to humoral mucosal immunity to influenza virus infection, are polymeric Igs present in many external secretions. In the present study, the quaternary structures of human S-IgA induced in nasal
Autor:
Tsuyoshi Tanaka, Kazuro Yoshida, Itsuro Ota, Tetsushi Toyonaga, Miho Saito, Kazuhiko Kotani, Mariko Oishi, Tadasu Nagaoka, Ryo Ito, Kazuya Yonezawa, Atsushi Ogo, Noriko Satoh-Asahara, Hiromichi Wada, Fumiko Miyanaga, Sumire Otani, Akira Shimatsu, Rika Araki, Hajime Yamakage, Taiichiro Okajima, Tsutomu Yamada, Masahiro Adachi
Publikováno v:
Endocrine Journal. 62:201-207
The aim of this study is to determine which indicator of chronic kidney disease most closely correlates with 10-year Framingham coronary heart disease (CHD) risk among serum creatinine, serum cystatin C (S-CysC), urine albumin-creatinine ratio (UACR)
Autor:
Kiyoshi Takagi, Jun Kanno, Atsushi Yokoyama, Akira Sugawara, Tetsuya Sato, Katsuhide Igarashi, Yasuyuki Ohkawa, Takashi Baba, Ryo Ito, Maky Otsuka, Yurina Shishido, Ken Ichirou Morohashi
Publikováno v:
Journal of Biological Chemistry. 289:18152-18162
Regulation of spatiotemporal gene expression in higher eukaryotic cells is critical for the precise and orderly development of undifferentiated progenitors into committed cell types of the adult. It is well known that dynamic epigenomic regulation (i