Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Ruimin Wang"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
Our recent study revealed that photobiomodulation (PBM) inhibits delayed neuronal death by preserving mitochondrial dynamics and function following global cerebral ischemia (GCI). In the current study, we clarified whether PBM exerts effective roles
Autor:
Jinyou Liu, Darrell W. Brann, Jing Wang, Ruimin Wang, Jason C. O'Connor, Jianhua Xu, Yujiao Lu, Quanguang Zhang, Yong Li, Gangadhara R. Sareddy, Ratna K. Vadlamudi, Yan Dong
Publikováno v:
The Journal of Neuroscience
17β-estradiol (E2) is produced from androgens via the action of the enzyme aromatase. E2 is known to be made in neurons in the brain, but its precise functions in the brain are unclear. Here, we used a forebrain-neuron-specific aromatase knock-out (
Publikováno v:
Molecular and cellular endocrinology. 535
Our previous study revealed that G-protein-coupled estrogen receptor-30 (GPR30) agonist G1 serves as a viable alternative neuroprotectant of 17β-estradiol (E2) to attenuate neuroinflammation and improve cognitive function after global cerebral ische
Publikováno v:
Nanoscale Research Letters. 16
Objective Esophageal squamous cell carcinoma (ESCC) is featured by early metastasis and late diagnosis. MicroRNA-301 (miR-301) is known to participate in diverse cancers. Nevertheless, effects of miR-301 on ESCC remain unexplored. Thus, we aim to exp
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-18 (2020)
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-18 (2020)
Background G-protein-coupled estrogen receptor (GPER/GPR30) is a novel membrane-associated estrogen receptor that can induce rapid kinase signaling in various cells. Activation of GPER can prevent hippocampal neuronal cell death following transient g
Autor:
Hongfeng Zhang, Lin Zhu, Fengpeng Wang, Ruimin Wang, Yujuan Hong, Yangqin Chen, Bin Zhu, Yue Gao, Hong Luo, Xian Zhang, Hao Sun, Ying Zhou, Yi Yao, Xin Wang
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Frontiers in Genetics
Frontiers in Genetics
Inwardly rectifying K+ channel 4.1 (Kir4.1), encoded by KCNJ10, is a member of the inwardly rectifying potassium channel family. In the brain, Kir4.1 is predominant in astrocytic glia and accounts for the spatial buffering of K+ released by neurons d
Publikováno v:
Molecular Neurobiology. 56:1852-1869
Hypothermia is currently the only approved therapy for global cerebral ischemia (GCI) after cardiac arrest; however, it unfortunately has multiple adverse effects. As a noninvasive procedure, photobiomodulation (PBM) therapy has emerged as a potentia
Publikováno v:
Redox Biology, Vol 16, Iss, Pp 285-293 (2018)
Redox Biology
Redox Biology
Traumatic brain injury (TBI) is a major cause of death and disability worldwide. Despite intense investigation, no neuroprotective agents for TBI have yet translated to the clinic. Recent efforts have focused on identifying potential therapeutic targ
Publikováno v:
Journal of Molecular Neuroscience. 61:42-51
Aberrant calcium influx is a common feature following ischemic reperfusion (I/R) in transient global cerebral ischemia (GCI) and causes delayed neuronal cell death in the CA1 region of the hippocampus. Activation of calcium-calmodulin (CaM) dependent
Autor:
Yingying Chen, Ruimin Wang, Dingjie Xu, Lijuan Zhang, Zhongqiu Wei, Na Mao, Guizhen Zhang, Xuemin Gao, Hui Zhang, Fuyu Jin, Wenchen Cai, Bonan Zhang, Shumin Li, Xue Yi, Xinyu Yang, Yi Zhang, Hong Xu, Fang Yang, Dan Li, Shifeng Li
Publikováno v:
Experimental cell research. 380(2)
Transforming growth factor-β1 (TGF-β1) alters the fibroblast phenotype by promoting transdifferentiation into myofibroblasts, which exhibit the ability to promote collagen synthesis and extracellular matrix (ECM) deposition, thereby playing a signi