Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Robert A. Anders"'
Autor:
Doreen N. Palsgrove, Brandi L. Cantarel, Andres Matoso, Steven C. Smith, Cristina R. Antonescu, Robert A. Anders, Regina Kwon, Carla Saoud, Naziheh Assarzadegan, Lysandra Voltaggio, Kiyoko Oshima, Jeffrey Gagan, Lei Zhang, Lisa M. Rooper, Pedram Argani
Publikováno v:
Am J Surg Pathol
We report a novel NIPBL-NACC1 gene fusion in a rare primary hepatic neoplasm previously described as the "cholangioblastic variant of intrahepatic cholangiocarcinoma." The 2 index cases were identified within our consultation files as morphologically
Autor:
Haiying Xu, Anil Kotte, Marina Baretti, Robert A. Anders, Feriyl Bhaijee, Marianna Zahurak, Timothy M. Pawlik, Elizabeth L. Engle, Ana De Jesus-Acosta, Qingfeng Zhu
Publikováno v:
Pancreas. 50:719-726
OBJECTIVES The aim of this study was to characterize the tumor microenvironment of patients with gastroenteropancreatic neuroendocrine tumors relative to progression-free survival (PFS). METHODS Immune profiling for CD3, CD8, programmed death-1/progr
Autor:
Margaret A. Tempero, Elizabeth M. Jaffee, Michael Considine, Elana J. Fertig, Beth Onners, Takahiro Tsujikawa, Robert H. Vonderheide, Julie M. Nauroth, Andrew H. Ko, Lisa M. Coussens, Dung T. Le, Dirk G. Brockstedt, Jennifer N. Durham, Daniel A. Laheru, George A. Fisher, Todd S. Crocenzi, Robert A. Anders, Elizabeth A. Sugar, Kim A. Reiss, Ludmila Danilova, Annie A. Wu
Publikováno v:
Clin Cancer Res
Purpose: Two studies in previously treated metastatic pancreatic cancer have been completed combining GVAX pancreas vaccine (GM-CSF–secreting allogeneic pancreatic tumor cells) with cyclophosphamide (Cy) and CRS-207 (live, attenuated Listeria monoc
Autor:
Sepideh Besharati, Enrico Ammirati, James B. Atkinson, JoAnn Lindenfeld, Javid Moslehi, Wouter C. Meijers, Robert A. Anders, Shi Huang, Lee S. Nguyen, D. Marshall Brinkley, Joe-Elie Salem, Kaushik Amancherla, Qingfeng Zhu, Arrush Choudhary
Publikováno v:
Circulation: Heart Failure. 14
Autor:
Daniela Cihakova, John Skinner, Marc K. Halushka, Jan M. Griffin, Robert A. Anders, Kavita Sharma, Katrina Rodriguez, Byoung Chol Oh, Stuart D. Russell, Monica V. Talor, Nisha A. Gilotra, Ilan S. Wittstein, Gerald Brandacher, Qingfeng Zhu, Roger A. Johns, William Bracamonte-Baran, Taejoon Won
Publikováno v:
Circulation: Heart Failure. 14
Background: The role of checkpoint axes in transplantation has been partially addressed in animal models but not in humans. Occurrence of fulminant myocarditis with allorejection-like immunologic features in patients under anti-PD1 (programmed death
Publikováno v:
Biochem Biophys Res Commun
PTEN and p53 are highly mutated in many cancers. These two tumor suppressors have critical functions in the nucleus, such as DNA repair, cell cycle progression, and genome maintenance. However, the in vivo functional relationship of nuclear PTEN and
Autor:
Won Jin Ho, Robert A. Anders, Ludmila Danilova, Mark Yarchoan, Elana J. Fertig, Teena Vithayathil, Nilofer S. Azad, Elizabeth M. Jaffee, Qingfeng Zhu, Ana De Jesus-Acosta, Daniel A. Laheru
Publikováno v:
Cancer Immunol Res
Immune-checkpoint therapy has failed to demonstrate meaningful clinical benefit in unselected cases of pancreatic adenocarcinoma (PDAC), but a subset of PDACs are known to upregulate pathways involved in acquired immune suppression. Further delineati
Autor:
Robert A. Anders, Theodore Ewachiw, William Matsui, Aykut Üren, Joey H. Li, Asma Begum, Ross McMillan, Zeshaan A. Rasheed, Yu-Tai Chang, Christian B. Gocke, Vesselin R. Penchev, Luigi Marchionni, Anirban Maitra, Qiuju Wang
Publikováno v:
Molecular Cancer Research. 17:929-936
Self-renewal maintains the long-term clonogenic growth that is required for cancer relapse and progression, but the cellular processes regulating this property are not fully understood. In many diseases, self-renewal is enhanced in cancer stem cells
Autor:
Benjamin Green, Aleksandra Ogurtsova, Paul Nghiem, Jennifer H. Yearley, Elizabeth L. Engle, Nirasha Ramchurren, Candice D. Church, Abha Soni, Genevieve J. Kaunitz, Steve Fling, Joel C. Sunshine, Julie E. Stein, Ludmila Danilova, Janis M. Taube, Farah Succaria, Tricia R. Cottrell, Natalie J. Miller, Peter Nguyen, Haiying Xu, Nicolas A. Giraldo, Lisa Lundgren, Robert A. Anders, Mac Cheever, Jonathan D. Cuda, Suzanne L. Topalian, Evan J. Lipson, Sneha Berry
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-11 (2018)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
Background We recently reported a 56% objective response rate in patients with advanced Merkel cell carcinoma (MCC) receiving pembrolizumab. However, a biomarker predicting clinical response was not identified. Methods Pretreatment FFPE tumor specime
Autor:
M Brinkley, Sepideh Besharati, A Choudhary, Wouter C. Meijers, Robert A. Anders, JoAnn Lindenfeld, Javid Moslehi, Qingfeng Zhu
Publikováno v:
European Heart Journal. 41
Background Acute cellular rejection remains a major cause of morbidity after heart transplantation with up to 30% of patients experiencing at least one rejection episode during the first year. Unfortunately, the mechanism underling rejection remains