Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Olle Söder"'
Publikováno v:
Nature Protocols. 13:248-259
We have recently developed a 3D culture system that allows the reorganization of rat primary testicular cells into organoids with a functional blood-testis barrier, as well as the establishment and maintenance of germ cells. The innovative aspect of
Autor:
Magdalena Kurek, Halima Albalushi, Jan-Bernd Stukenborg, Luise Landreh, Olle Söder, Leif Karlsson, Outi Hovatta, Kristín Rós Kjartansdóttir
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Stem Cells International
Stem Cells International
Human embryonic stem (hES) cells represent an important tool to study early cell development. The previously described use of human recombinant laminin (LN) 521 represented a step forward in generating clinically safe culture conditions. To test the
Autor:
Wieland Kiess, Giuseppe D'Agostino, Eewa Nånberg, Sebastiano Trattaro, Åke Bergman, Rantakkoko P, Chris Gennings, Leemans M, Carl G. Bornehag, Matteo Zanella, Filip Rendel, Pauliina Damdimopoulou, Vesna Munic Kos, Giuseppe Testa, Demeneix B, Cavallo F, Efthymia Kitraki, Fini J, Raul Bardini Bressan, Chorev Ne, Joachim Sturve, Joëlle Rüegg, Birgitta E. Sundström, Steven M. Pollard, Christina Rudén, Nicolò Caporale, Birgersson L, Pierre-Luc Germain, Alejandro Lopez Tobon, Borbély G, Jönsson M, Hannu Kiviranta, Olle Söder, Lazzarin M, Mattias Öberg
Convergent evidence associates endocrine disrupting chemicals (EDCs) with major, increasingly-prevalent human disorders. Regulation requires elucidation of EDC-triggered molecular events causally linked to adverse health outcomes, but two factors lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c48cdda85e2bd85f6618bd93559608a
Autor:
Olle Söder, Kirsi Jahnukainen, Timo Jahnukainen, A Vatanen, Mi Hou, Ulla M. Saarinen-Pihkala, Tiina Ojala, Maila Turanlahti, Taisto Sarkola, T Huang, M. Kurimo
Publikováno v:
Bone marrow transplantation. 52(4)
The aim of this study was to analyze the prevalence of frailty and physical health limitations among long-term survivors of high-risk neuroblastoma (HR NBL) and to investigate whether frail health is associated with variables of cardiovascular functi
Publikováno v:
Journal of Steroids & Hormonal Science. 7
The secretory insulin-like growth factor-binding protein-3 (IGFBP-3) induces apoptosis via both insulin-like growth factor-I (IGF-I)-dependent and -independent mechanisms. Here, we have examined the effects of IGFBP-3 on Leydig cell apoptosis, prolif
Publikováno v:
International Journal of Andrology. 32:66-73
Elimination of contaminating malignant cells is crucial to avoiding cancer relapse in association with transplantation of autologous spermatogonial stem cells. In the clinical setting, there is presently no effective procedure for separating testicul
Autor:
Kirsi Jahnukainen, Olle Söder, Farasat Zaman, Jorma Toppari, Mirja Nurmio, Anna-Maria Andersson, Jorma Paranko
Publikováno v:
International Journal of Andrology. 30:366-376
The tyrosine kinase receptor c-kit and its interaction with the ligand, stem cell factor (SCF), play an essential role in the developing testis. C-kit is important for the development of the Leydig cells and for the migration, proliferation and survi
Leydig cell steroidogenesis unexpectedly escapes mitochondrial dysfunction in prematurely aging mice
Autor:
Olle Söder, Luise Landreh, Jan Nedergaard, Nina Atanassova, Natasa Petrovic, Mi Hou, Daniel Edgar, Irina G. Shabalina, Kjell Hultenby, Natalia Gibanova, Konstantin Svechnikov
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 29(8)
Point mutations and deletions of mitochondrial DNA (mtDNA) accumulate in tissues during aging in animals and humans and are the basis for mitochondrial diseases. Testosterone synthesis occurs in the mitochondria of Leydig cells. Mitochondrial dysfunc
Publikováno v:
Human Reproduction. 21:2801-2809
BACKGROUND: The high mobility group box chromosomal protein 1 (HMGB1) was originally shown to be a nuclear DNA-binding protein that activates transcription and promotes differentiation. More recently, there have been reports that HMGB1 may also funct
Autor:
Olle Söder, J. De Kock, Michael Landreh, Ellen Goossens, Jan-Bernd Stukenborg, Hans Jörnvall, Yoni Baert
Publikováno v:
Human reproduction (Oxford, England). 30(2)
Study question: Is it possible to derive a scaffold from human testis for the purpose of tissue engineering and regenerative medicine? Summary answer: We developed a method to produce a cytocompatible decellularized testicular matrix (DTM) while main