Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Moshe Yaniv"'
Autor:
Moshe Yaniv, Oliver Distler, Alfiya Akhmetshina, Jérôme Avouac, Katrin Palumbo, Michal Tomcik, Pawel Zerr, Clara Dees, Jörg H W Distler, Georg Schett, Stefan Vollath
Publikováno v:
Annals of the Rheumatic Diseases. 70:1320-1326
Objectives Transforming growth factor β (TGFβ) has been identified as a key player in fibrotic diseases. However, the molecular mechanisms by which TGFβ activates fibroblasts are incompletely understood. Here, the role of JunD, a member of the act
Autor:
Pierre Chambon, Charles W. M. Roberts, Hasan Siddiqui, Moshe Yaniv, Christian Muchardt, Erik S. Knudsen, David A. Solomon, Ryan J. Bourgo, Daniel Metzger, Sejal R. Fox, Courtney G. Sansam
Publikováno v:
Molecular Biology of the Cell. 20:3192-3199
Switch (SWI)/sucrose nonfermentable (SNF) is an evolutionarily conserved complex with ATPase function, capable of regulating nucleosome position to alter transcriptional programs within the cell. It is known that the SWI/SNF complex is responsible fo
Publikováno v:
European Journal of Biochemistry. 106:25-31
The binding sites of calf thymus RNA polymerase (B) II, wheat germ RNA polymerase B and of the Escherichia coli RNA polymerase were mapped on the simian virus 40 genome by observation of enzyme-linear DNA complexes by electron microscopy. Three to fo
Autor:
David N. Reisman, Bryan L. Betz, Bernard E. Weissman, William K. Funkhouser, Matthew W. Strobeck, Christian Murchardt, Janiece Sciariotta, Larry S. Sherman, Erik S. Knudsen, Moshe Yaniv
Publikováno v:
Oncogene. 21:1196-1207
Mammalian cells express two homologs of the SWI2 subunit of the SWI/SNF chromatin-remodeling complex called BRG1 and BRM. Whether the SWI/SNF complexes formed by these two subunits perform identical or different functions remains an important questio
Autor:
Kenneth S. Polonsky, Markus Stoffel, Moshe Yaniv, Karla N. Munoz, David Q. Shih, Marco Pontoglio, Seamus Screenan, Lou Philipson
Publikováno v:
Diabetes. 50:2472-2480
Mutations in hepatocyte nuclear factor 1alpha (HNF-1alpha) lead to maturity-onset diabetes of the young type 3 as a result of impaired insulin secretory response in pancreatic beta-cells. The expression of 50 genes essential for normal beta-cell func
Autor:
Moshe Yaniv, Benoit Viollet, Evi Soutoglou, Martine Vaxillaire, Iannis Talianidis, Marco Pontoglio
Publikováno v:
The EMBO Journal. 20:1984-1992
CREB-binding protein (CBP) and CBP-associated factor (P/CAF) are coactivators possessing an intrinsic histone acetyltransferase (HAT) activity. They are positioned at promoter regions via association with sequence-specific DNA-binding factors and sti
Publikováno v:
The Journal of Experimental Medicine
The terminal components of the complement system contribute to host defense by forming the multiprotein membrane attack complex (MAC) which is responsible for cell lysis and several noncytotoxic effects. Most of the complement proteins are synthesize
Autor:
Moshe Yaniv, Christian Muchardt
Publikováno v:
Journal of Molecular Biology. 293:187-198
SWI/SNF, RSC, NURF, CHRAC, ACF, RSF and NuRD are highly conserved multiprotein complexes that use the energy of ATP-hydrolysis to remodel chromatin. These complexes that have different subunit composition, all rely on helicase-like enzymes for ATPase
Publikováno v:
Virology. 242(2):378-386
The human papillomavirus type 18 E1 and E2 proteins are both required for the initiation of viral DNA replication. Whereas E2 is the major viral transcription regulator, E1 is the replication initiator protein. They interact with each other and with
Publikováno v:
The EMBO Journal. 17:223-231
The brm and BRG-1 proteins are mutually exclusive subunits of the mammalian SWI-SNF complex. Within this complex, they provide the ATPase activity necessary for transcriptional regulation by nucleosome disruption. Both proteins were recently found to