Zobrazeno 1 - 10
of 786
pro vyhledávání: '"McMillan A"'
Autor:
Elli Papaemmanuil, Amy A Kirkwood, Andrew McMillan, Eleanor J. Ward, David I. Marks, Amir Enshaei, Claire Schwab, Daniel Leongamornlert, Pip Patrick, Ellie Butler, Emilio Barretta, Christine J. Harrison, Clare J. Rowntree, Laura Clifton-Hadley, Tom Creasey, Bela Patel, Adele K. Fielding, Anthony V. Moorman, Tobias Menne, Katie Twentyman
Publikováno v:
Leukemia. 36:625-636
Chromosomal abnormalities are established prognostic markers in adult ALL. We assessed the prognostic impact of established chromosomal abnormalities and key copy number alterations (CNA) among 652 patients with B-cell precursor ALL treated on a mode
Autor:
Philip A. Cook, David J. Irwin, Ilya M. Nasrallah, Corey T. McMillan, Jacob Dubroff, Fulvio Da Re, James C. Gee, Christopher Olm, Murray Grossman, Frederick J. Nitchie, Jeffrey S. Phillips
Publikováno v:
Alzheimer's & Dementia. 18:1235-1247
Introduction Longitudinal positron emission tomography (PET) studies of tau accumulation in Alzheimer's disease (AD) have noted reduced increases or frank decreases in tau signal. We investigated how such reductions related to analytical confounds an
Autor:
Dale Porter, Alessandra Ianari, Merissa Brousseau, Patrick McCarren, Foxy P. Robinson, Adam Skepner, Virendar K. Kaushik, Kathleen M. Mulvaney, Arthur J. Campbell, Martin J Drysdale, Zachary Mullin-Bernstein, Brian J. McMillan, Robert Hilgraf, Ritu Singh, Matthew J. Ranaghan, Meghan O’Keefe, William R. Sellers, David C. McKinney, Jamie A. Moroco, Michael F. Mesleh, David E. Timm, Besnik Bajrami, Florence F. Wagner
Publikováno v:
J Med Chem
PRMT5 and its substrate adaptor proteins (SAPs), pICln and Riok1, are synthetic lethal dependencies in MTAP-deleted cancer cells. SAPs share a conserved PRMT5 binding motif (PBM) which mediates binding to a surface of PRMT5 distal to the catalytic si
Publikováno v:
Vaccine. 39:3590-3601
Helicobacter pylori (Hp) colonizes the human gastric mucosa with a high worldwide prevalence. Currently, Hp can be eradicated by the use of antibiotics. Due to the increase of antibiotic resistance, new therapeutic strategies need to be devised: one
Publikováno v:
Biophysical Journal. 120:2521-2531
DNA looping plays an important role in cells in both regulating and protecting the genome. Often, studies of looping focus on looping by prokaryotic transcription factors like lac repressor or by structural maintenance of chromosomes (SMC) proteins s
Autor:
Alberto A. Amarilla, David A. Muller, Naphak Modhiran, Nigel A.J. McMillan, Aroon Supramaniam, Ariel Isaacs, Jovin J Y Choo, Helle Bielefeldt-Ohmann, Christopher L. D. McMillan, Adi Idris, Gabrielle E. Kelly, Michael J. Landsberg, Germain J. P. Fernando, Stacey T. M. Cheung, Daniel Watterson, Benjamin Liang, Armira Azuar, Paul R. Young, Alexander A. Khromykh, Dhruba Acharya
Publikováno v:
Science Advances
Description
Delivery of a SARS-CoV-2 vaccine to the skin of mice via microarray patches provides complete protection from challenge.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 160 million people and
Delivery of a SARS-CoV-2 vaccine to the skin of mice via microarray patches provides complete protection from challenge.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 160 million people and
Autor:
Christopher L. D. McMillan, Armira Azuar, Helle Bielefeldt-Ohmann, Gabrielle E. Kelly, Germain J. P. Fernando, David A. Muller, Ariel Isaacs, Daniel Watterson, Paul R. Young, Alberto A. Amarilla, Michael J. Landsberg, Nigel A.J. McMillan, Alexander A. Khromykh, Naphak Modhiran, Benjamin Liang, Stacey T. M. Cheung, Jovin J Y Choo, Dhruba Acharya, Adi Idris, Aroon Supramaniam
SARS-CoV-2 has infected over 160 million people and resulted in more than 3.3 million deaths, and we still face many challenges in the rollout of vaccines. Here, we use the high-density microarray patch to deliver a SARS-CoV-2 spike subunit vaccine d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81b1d6149fad1e334031f3cdabd3ac3c
https://doi.org/10.1101/2021.05.30.446357
https://doi.org/10.1101/2021.05.30.446357
Publikováno v:
ChemBioChem. 21:3249-3254
The ϵ subunit of ATP synthases has been proposed to regulate ATP hydrolysis in bacteria. Prevailing evidence supports the notion that when the ATP concentration falls below a certain threshold, the ϵ subunit changes its conformation from a non-inhi
Autor:
Rebecca C. Spillmann, Nissan V. Baratang, Kym M. Boycott, Karen W. Gripp, Taila Hartley, Anik St-Denis, Philippe M. Campeau, Kristin D. Kernohan, Erik A. Eklund, Jessica L. Zambonin, Loren D M Pena, Michael T. Geraghty, Andrew C. Edmondson, Jacek Majewski, Hugh J. McMillan, Allan Bayat, Miao He, Manuela Pendziwiat, Eric Bareke, Andrea Guerin, Thi Tuyet Mai Nguyen, Julie Richer, Devon L. Johnstone, Hilde M. H. Braakman
Publikováno v:
Johnstone, D L, Nguyen, T T M, Zambonin, J, Kernohan, K D, St-Denis, A, Baratang, N V, Hartley, T, Geraghty, M T, Richer, J, Majewski, J, Bareke, E, Guerin, A, Pendziwiat, M, Pena, L D M, Braakman, H M H, Grip, K W, Edmondson, A C, He, M, Spillmann, R C, Eklund, E A, Bayat, A, Network, U D, McMillan, H J, Boycott, K M, Campeau, P M & Care4Rare Canada Consortium 2020, ' Early infantile epileptic encephalopathy due to biallelic pathogenic variants in PIGQ : Report of seven new subjects and review of the literature ', Journal of Inherited Metabolic Disease, vol. 43, no. 6, pp. 1321-1332 . https://doi.org/10.1002/jimd.12278
Journal of Inherited Metabolic Disease
Journal of Inherited Metabolic Disease
We investigated seven children from six families to expand the phenotypic spectrum associated with an early infantile epileptic encephalopathy caused by biallelic pathogenic variants in the phosphatidylinositol glycan anchor biosynthesis class Q (PIG
Autor:
Angelina M. Dichiera, Andrew J. Esbaugh, Till S. Harter, Olivia J. L. McMillan, Colin J. Brauner, Jonathan M. Wilson
Publikováno v:
Physiological and Biochemical Zoology. 92:554-566
Pacific spiny dogfish (Squalus suckleyi) have been widely used as a representative species for chondrichthyan CO2 excretion. Pacific spiny dogfish have a slower red blood cell (RBC) carboni...