Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Majon Muller"'
Autor:
Majon Muller, Willem P.Th.M. Mali, Y. van der Graaf, Hadassa M. Jochemsen, Anne M. Grool, Koen L. Vincken, Mirjam I. Geerlings
Publikováno v:
Journal of Alzheimer's Disease. 29:39-49
High levels of angiotensin-converting-enzyme (ACE) may increase the risk of dementia through blood pressure elevation and subsequent development of cerebral small-vessel disease. However, high ACE levels may also decrease this risk through amyloid de
Autor:
Yolanda van der Graaf, Frank L.J. Visseren, Ale Algra, Majon Muller, Mirjam I. Geerlings, Hadassa M. Jochemsen
Publikováno v:
Jochemsen, H M, Geerlings, M I, Visseren, F L, Algra, A, van der Graaf, Y & Muller, M 2012, ' Serum angiotensin-converting enzyme and recurrent vascular events. The SMART-MR study ', Atherosclerosis, vol. 224, no. 2, pp. 486-491 . https://doi.org/10.1016/j.atherosclerosis.2012.07.010
Atherosclerosis, 224(2), 486-491. Elsevier Ireland Ltd
Atherosclerosis, 224(2), 486-491. Elsevier Ireland Ltd
Objective Chronic exposure to high levels of angiotensin-converting enzyme (ACE) might increase the risk of hypertensive cardiovascular events. However, little data are available on the association of direct measures of ACE activity with vascular ris
Autor:
Emma L. Ashby, Charlotte E. Teunissen, Majon Muller, Mirjam I. Geerlings, Hadassa M. Jochemsen, Ruth E. Jones, Mike P. Wattjes, Philip Scheltens, Wiesje M. van der Flier, Patrick G. Kehoe
Publikováno v:
Journal of Alzheimer's Disease, 44(1), 153-162. IOS Press
Journal of Alzheimer's Disease, 44(1), 153-162
Jochemsen, H M, van der Flier, W M, Ashby, E L, Teunissen, C E, Jones, R E, Wattjes, M P, Scheltens, P, Geerlings, M I, Kehoe, P G & Muller, M 2015, ' Angiotensin-Converting Enzyme in Cerebrospinal Fluid and Risk of Brain Atrophy ', Journal of Alzheimer's Disease, vol. 44, no. 1, pp. 153-162 . https://doi.org/10.3233/JAD-131496
Journal of Alzheimer's Disease, 44(1), 153-162
Jochemsen, H M, van der Flier, W M, Ashby, E L, Teunissen, C E, Jones, R E, Wattjes, M P, Scheltens, P, Geerlings, M I, Kehoe, P G & Muller, M 2015, ' Angiotensin-Converting Enzyme in Cerebrospinal Fluid and Risk of Brain Atrophy ', Journal of Alzheimer's Disease, vol. 44, no. 1, pp. 153-162 . https://doi.org/10.3233/JAD-131496
Background Higher angiotensin-converting enzyme (ACE) activity might increase the risk of Alzheimer's disease by increasing blood pressure, and subsequent development of cerebral small vessel disease (CSVD). Yet, it may also decrease this risk, as it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::287e73d314813683f320a58e38c594b9
https://hdl.handle.net/1887/103147
https://hdl.handle.net/1887/103147
Publikováno v:
Nakhai-Pour, H R, Grobbee, D E, Bots, M L, Muller, M & Van der Schouw, Y T 2007, ' C-reactive protein and aortic stiffness and wave reflection in middle-aged and elderly men from the community ', Journal of Human Hypertension, vol. 21, no. 12, pp. 949-955 . https://doi.org/10.1038/sj.jhh.1002255
Journal of Human Hypertension, 21(12), 949-955. Nature Publishing Group
Journal of Human Hypertension, 21(12), 949-955. Nature Publishing Group
High plasma C-reactive protein (hs-CRP) levels and arterial stiffness are risk factors for cardiovascular diseases. Pulse wave velocity (PWV) and augmentation index (AIx) have been found to be elevated in patients with vascular inflammation, diabetes
Publikováno v:
Clinical Endocrinology, 66(3), 394-398. Wiley-Blackwell
Pour, H R N, Grobbee, D E, Muller, M & Van Der Schouw, Y T 2007, ' Association of endogenous sex hormone with C-reactive protein levels in middle-aged and elderly men ', Clinical Endocrinology, vol. 66, no. 3, pp. 394-398 . https://doi.org/10.1111/j.1365-2265.2007.02745.x
Pour, H R N, Grobbee, D E, Muller, M & Van Der Schouw, Y T 2007, ' Association of endogenous sex hormone with C-reactive protein levels in middle-aged and elderly men ', Clinical Endocrinology, vol. 66, no. 3, pp. 394-398 . https://doi.org/10.1111/j.1365-2265.2007.02745.x
Summary Background In women, postmenopausal oestrogen supplementation increases levels of systemic markers of inflammation, which are important predictors of coronary heart disease (CHD) risk. Whether endogenous sex hormone levels in men are also rel
Autor:
Yvonne T. van der Schouw, Diederick E. Grobbee, Marielle H. Emmelot-Vonk, Majon Muller, Hamid Reza Nakhai Pour
Publikováno v:
European Journal of Endocrinology, 155(6), 887-893. BioScientifica Ltd.
Pour, H R N, Grobbee, D E, Muller, M, Emmelot-Vonk, M & van der Schouw, Y T 2006, ' Serum sex hormone and plasma homocysteine levels in middle-aged and elderly men ', European Journal of Endocrinology, vol. 155, no. 6, pp. 887-893 . https://doi.org/10.1530/eje.1.02303
Pour, H R N, Grobbee, D E, Muller, M, Emmelot-Vonk, M & van der Schouw, Y T 2006, ' Serum sex hormone and plasma homocysteine levels in middle-aged and elderly men ', European Journal of Endocrinology, vol. 155, no. 6, pp. 887-893 . https://doi.org/10.1530/eje.1.02303
Objective: To investigate whether circulating levels of testosterone (total, bioavailable), estradiol (total, bioavailable), and DHEA sulfate (DHEAS) are associated with fasting plasma homocysteine (tHcy) levels in middle-aged and elderly men. Design
Autor:
Hadassa M. Jochemsen, Mirjam I. Geerlings, Wiesje M. van der Flier, Philip Scheltens, Majon Muller, Emma L. Ashby, Ruth E. Jones, Patrick G. Kehoe, Charlotte E. Teunissen
Publikováno v:
Alzheimer's Research and Therapy, 6(3)
Alzheimer's Research & Therapy, 6(3):27. BioMed Central
Alzheimer's Research & Therapy
Jochemsen, H M, Teunissen, C E, Ashby, E L, van der Flier, W M, Jones, R E, Geerlings, M I, Scheltens, P, Kehoe, P G & Muller, M 2014, ' The association of angiotensin-converting enzyme with biomarkers for Alzheimer's disease ', Alzheimer's Research & Therapy, vol. 6, no. 3, 27, pp. 27 . https://doi.org/10.1186/alzrt257
Alzheimer's Research & Therapy, 6(3):27. BioMed Central
Alzheimer's Research & Therapy
Jochemsen, H M, Teunissen, C E, Ashby, E L, van der Flier, W M, Jones, R E, Geerlings, M I, Scheltens, P, Kehoe, P G & Muller, M 2014, ' The association of angiotensin-converting enzyme with biomarkers for Alzheimer's disease ', Alzheimer's Research & Therapy, vol. 6, no. 3, 27, pp. 27 . https://doi.org/10.1186/alzrt257
Introduction Lower angiotensin-converting enzyme (ACE) activity could increase the risk of Alzheimer’s disease (AD) as ACE functions to degrade amyloid-β (Aβ). Therefore, we investigated whether ACE protein and activity levels in cerebrospinal fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5135e3a1b835852bf0a10d0e8140378b
http://hdl.handle.net/1887/103686
http://hdl.handle.net/1887/103686
Autor:
Yvonne T. van der Schouw, Majon Muller, Isolde den Tonkelaar, Diederick E. Grobbee, Steven W. J. Lamberts
Publikováno v:
Journal of Clinical Endocrinology and Metabolism, 90(5), 2618-2623. The Endocrine Society
Muller, M, Grobbee, D E, Den Tonkelaar, I, Lamberts, S W J & Van Der Schouw, Y T 2005, ' Endogenous sex hormones and metabolic syndrome in aging men ', Journal of Clinical Endocrinology and Metabolism, vol. 90, no. 5, pp. 2618-2623 . https://doi.org/10.1210/jc.2004-1158
Journal of Clinical Endocrinology and Metabolism, 90(5), 2618-2623. Endocrine Society
Muller, M, Grobbee, D E, Den Tonkelaar, I, Lamberts, S W J & Van Der Schouw, Y T 2005, ' Endogenous sex hormones and metabolic syndrome in aging men ', Journal of Clinical Endocrinology and Metabolism, vol. 90, no. 5, pp. 2618-2623 . https://doi.org/10.1210/jc.2004-1158
Journal of Clinical Endocrinology and Metabolism, 90(5), 2618-2623. Endocrine Society
Background: Sex hormone levels in men change during aging. These changes may be associated with insulin sensitivity and the metabolic syndrome. Methods: We studied the association between endogenous sex hormones and characteristics of the metabolic s
Autor:
Huibert A. P. Pols, Majon Muller, Diederick E. Grobbee, Yvonne T. van der Schouw, Frank H. de Jong, Frank H. Pierik, Louis Gooren, Willem de Ronde, Rob F. A. Weber
Publikováno v:
Clinical Endocrinology, 62(4), 498-503. Wiley-Blackwell Publishing Ltd
Clinical Endocrinology, 62(4), 498-503. Wiley
De Ronde, W, Van Der Schouw, Y T, Pierik, F H, Pols, H A P, Muller, M, Grobbee, D E, Gooren, L J G, Weber, R F A & De Jong, F H 2005, ' Serum levels of sex hormone-binding globulin (SHBG) are not associated with lower levels of non-SHBG-bound testosterone in male newborns and healthy adult men ', Clinical Endocrinology, vol. 62, no. 4, pp. 498-503 . https://doi.org/10.1111/j.1365-2265.2005.02252.x
Clinical Endocrinology, 62(4), 498-503. Wiley-Blackwell
Clinical Endocrinology, 62(4), 498-503. Wiley
De Ronde, W, Van Der Schouw, Y T, Pierik, F H, Pols, H A P, Muller, M, Grobbee, D E, Gooren, L J G, Weber, R F A & De Jong, F H 2005, ' Serum levels of sex hormone-binding globulin (SHBG) are not associated with lower levels of non-SHBG-bound testosterone in male newborns and healthy adult men ', Clinical Endocrinology, vol. 62, no. 4, pp. 498-503 . https://doi.org/10.1111/j.1365-2265.2005.02252.x
Clinical Endocrinology, 62(4), 498-503. Wiley-Blackwell
Objective It is generally accepted that SHBG decreases the bioavailability and activity of testosterone (T). In in vitro experiments increased levels of SHBG will be associated with decreased levels of non-SHBG bound testosterone (non-SHBG-T). Howeve
Autor:
Majon Muller, Yvonne T. van der Schouw, Frank H. de Jong, Louis Gooren, Willem de Ronde, Diederick E. Grobbee, Huibert A. P. Pols
Publikováno v:
Journal of Clinical Endocrinology and Metabolism, 90(1), 157-162. Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 90(1), 157-162. The Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 90(1), 157-162. ENDOCRINE SOC
De Ronde, W, Van Der Schouw, Y T, Muller, M, Grobbee, D E, Gooren, L J G, Pols, H A P & De Jong, F H 2005, ' Associations of Sex-Hormone-Binding Globulin (SHBG) with Non-SHBG-Bound levels of testosterone and estradiol in independently living men ', Journal of Clinical Endocrinology and Metabolism, vol. 90, no. 1, pp. 157-162 . https://doi.org/10.1210/jc.2004-0422
Journal of Clinical Endocrinology and Metabolism, 90(1), 157. The Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 90(1), 157-162. The Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 90(1), 157-162. ENDOCRINE SOC
De Ronde, W, Van Der Schouw, Y T, Muller, M, Grobbee, D E, Gooren, L J G, Pols, H A P & De Jong, F H 2005, ' Associations of Sex-Hormone-Binding Globulin (SHBG) with Non-SHBG-Bound levels of testosterone and estradiol in independently living men ', Journal of Clinical Endocrinology and Metabolism, vol. 90, no. 1, pp. 157-162 . https://doi.org/10.1210/jc.2004-0422
Journal of Clinical Endocrinology and Metabolism, 90(1), 157. The Endocrine Society
Results of in vitro experiments indicate that with increasing concentrations of SHBG, testosterone ( T) is preferentially bound to SHBG in comparison with estradiol (E2). In these studies, the ratio of non-SHBG-bound E2 (non-SHBG-E2) to non-SHBG-T in