Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mahadevan Rajasekaran"'
Autor:
Anjali S Iyangar, Rohan Reddy, Jaideep Chakladar, Mahadevan Rajasekaran, Kyoko Sakamoto, Valmik Bhargava, Wei Tse Li, Weg M. Ongkeko
Publikováno v:
Cancers
Volume 13
Issue 15
Cancers, Vol 13, Iss 3649, p 3649 (2021)
Volume 13
Issue 15
Cancers, Vol 13, Iss 3649, p 3649 (2021)
Simple Summary The abundance of microbial species residing within tumors is correlated to cancer progression across many different cancers, including bladder cancer. However, links between the intratumor microbiome of muscle invasive bladder cancer (
Publikováno v:
Urology. 69:791-794
OBJECTIVES The molecular mechanisms by which potassium induces urinary bladder hyperactivity are not clear. In the present study, we tested our hypothesis that potassium chloride (KCl)-induced bladder hyperactivity might be mediated through a calcium
Autor:
Paul C. Stein, Marianne Chenoweth, Amir H. Arsanjani, C. Lowell Parsons, Mahadevan Rajasekaran
Publikováno v:
Urology. 69:577-581
Tamm-Horsfall protein (THP) from normal urine has been shown to protect against the cytotoxic effects of toxic urinary cations (TFs) in vivo and in vitro. This study investigated the effect of desialylation on the cytoprotective activity of THP.From
Publikováno v:
BJU International. 98:430-434
OBJECTIVE To evaluate the effects of MN-001, a novel orally active anti-inflammatory agent, in suppressing the bladder hyperactivity resulting from ovalbumin (OA)-induced mast-cell stimulation in a rat model. MATERIALS AND METHODS Sprague-Dawley rats
Publikováno v:
Neurourology and Urodynamics. 24:295-300
Aims Spontaneously hypertensive rats (SHR) exhibit overactive bladder (OAB) symptoms and have an up-regulated calcium sensitizing RhoA/Rho-kinase pathway in their vascular smooth muscle tissues. This study examined the role of RhoA/Rho-kinase pathway
Autor:
Wayne J.G. Hellstrom, Suresh C. Sikka, Mahadevan Rajasekaran, I-Li Chen, Krishna C. Agrawal, Debasis Mondal
Publikováno v:
Journal of Urology. 160:2210-2215
Purpose: Nitric oxide (NO) synthesized by nitric oxide synthase (NOS) is recognized as the central mediator of penile erection. This process appears to be mediated mainly by neuronal NOS (nNOS), which is localized to the nonadrenergic, noncholinergic
Publikováno v:
Fertility and Sterility. 64:166-171
Objective To quantify the levels of reactive oxygen species, superoxide dismutase (SOD), and interleukins (IL) 2 and 8 in seminal plasma of infertile patients as well as to examine the possible relationship between oxidative stress and proinflammator
Publikováno v:
Contraception. 47:401-412
The ethyl acetate fraction of Mollugo pentaphylla, a tropical herb, contains an antifungal saponin (mollugogenol-A). We report here the spermicidal effects of this saponin. Washed sperm (100 x 10(6) with50% motility) from normal volunteers were incub
Publikováno v:
BJU international. 104(2)
OBJECTIVES To evaluate whether rat fetal brain stem cells can be induced to acquire cell fates outside the nervous system, hypothesising that cell-based replacement therapy with stem cells can aid in the regeneration of penile smooth musculature and
Publikováno v:
Urology. 66(4)
To test whether the presence of Tamm-Horsfall protein (THP) can limit the injury caused by low-molecular-weight (LMW) urinary cations using an in vivo rat bladder injury model. Previous studies have shown that normal urine contains LMW cations toxic