Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Luigi D. Notarangelo"'
Autor:
Limin Wang, Julián Candia, Lichun Ma, Yongmei Zhao, Luisa Imberti, Alessandra Sottini, Eugenia Quiros-Roldan, Kerry Dobbs, Peter D. Burbelo, Jeffrey I. Cohen, Ottavia M. Delmonte, Marshonna Forgues, Hui Liu, Helen F. Matthews, Elana Shaw, Michael A. Stack, Sarah E. Weber, Yu Zhang, Andrea Lisco, Irini Sereti, Helen C. Su, Luigi D. Notarangelo, Xin Wei Wang
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the pandemic respiratory infectious disease COVID-19. However, clinical manifestations and outcomes differ significantly among COVID-19 patients, ranging from asymptomati
Autor:
Elise M. N. Ferré, Alexandra F. Freeman, Jean Ulrick, Eugenia Quiros-Roldan, Amanda Urban, Jessica Durkee-Shock, Monica M. Schmitt, Jenna R.E. Bergerson, Christine Lafeer, Justina Pfister, Deborah Draper, Tom DiMaggio, Luigi D. Notarangelo, Marita Bosticardo, Luisa Imberti, Michael D. Keller, David H. McDermott, Michail S. Lionakis, Dimana Dimitrova, Emily Ricotta, Jeffrey I. Cohen, Steven M. Holland, V. Koneti Rao, Ottavia M. Delmonte, Peter D. Burbelo, Kerry Dobbs, Meng Truong, Dawn Shaw
Publikováno v:
The Journal of Allergy and Clinical Immunology
Background SARS-CoV-2 vaccination is recommended in patients with inborn errors of immunity (IEIs); however, little is known about immunogenicity and safety in these patients. Objective We sought to evaluate the impact of genetic diagnosis, age, and
Publikováno v:
British Journal of Clinical Pharmacology. 88:2500-2508
Inborn errors of immunity consist of over 400 known single gene disorders that may manifest with infection susceptibility, autoimmunity, autoinflammation, hypersensitivity and cancer predisposition. Most patients are treated symptomatically with immu
Autor:
Valentina Discepolo, Meng Truong, Sayonara Mato, Andrea Lo Vecchio, Luigi D. Notarangelo, Yazmin Espinosa, Jane C. Burns, Ottavia M. Delmonte, Ugo Ramenghi, Camillo Rossi, Emma Rey, Peter D. Burbelo, Kerry Dobbs, Dana Gerstbacher, Daniela Montagna, Riccardo Castagnoli, Gina A. Montealegre Sanchez, Lesia K. Dropulic, Loreani P Noguera, Francesco Licciardi, Luisa Imberti, Helen C. Su, Maria Cecilia Vial, Adriana H. Tremoulet, John A. Chiorini, Amelia Licari, Blake M. Warner, Karyl S. Barron, Eli M Eisenstein, Jeffrey I. Cohen, Alfredo Guarino, Gian Luigi Marseglia, María Cecilia Poli, John T. Kanegaye, Chisato Shimizu
The autoantibody profile associated with known autoimmune diseases in patients with COVID-19 or multisystem inflammatory syndrome in children (MIS-C) remains poorly defined. Here we show that adults with COVID-19 had a moderate prevalence of autoanti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c4e14d9023d302dde2d3b28536660f0
https://doi.org/10.1101/2021.11.03.21265769
https://doi.org/10.1101/2021.11.03.21265769
Autor:
Michael Tsui, Weixian Min, Stephanie Ng, Kerry Dobbs, Luigi D. Notarangelo, Yigal Dror, Eyal Grunebaum
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Inherited defects that abrogate the function of the adenosine deaminase (ADA) enzyme and consequently lead to the accumulation of toxic purine metabolites cause profound lymphopenia and severe combined immune deficiency. Additionally, neutropenia and
Autor:
Alessandro Re, Giuseppe Rossi, Luigi D. Notarangelo, Angelo Belotti, Valeria Cancelli, Helen C. Su, Jeffrey I. Cohen, A. Anastasia, Luisa Imberti, Virginia Quaresima, Chiara Pagani, Chiara Cattaneo, Alessandra Tucci, Peter D. Burbelo, John A. Chiorini, Kerry Dobbs, Alessandra Sottini
Publikováno v:
Blood Cancer Journal
Blood Cancer Journal, Vol 11, Iss 9, Pp 1-7 (2021)
Blood Cancer Journal, Vol 11, Iss 9, Pp 1-7 (2021)
The ability of patients with hematologic malignancies (HM) to develop an effective humoral immune response after COVID-19 is unknown. A prospective study was performed to monitor the immune response to SARS-CoV-2 of patients with follicular lymphoma
Autor:
Jenna R.E. Bergerson, Tom DiMaggio, Elise M. N. Ferré, Monica M. Schmitt, Luigi D. Notarangelo, Michail S. Lionakis, Sebastian Ochoa, Jennifer Stoddard, Shakuntala Rampertaap, Sergio D. Rosenzweig, Peter D. Burbelo, Elana R. Shaw, Steven M. Holland, Lindsey B. Rosen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Patients with the monogenic immune dysregulatory syndrome autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), which is caused by loss-of-function mutations in the autoimmune regulator (AIRE) gene, uniformly carry neutralizing aut
Autor:
Francesca Ferrua, Ileana Bortolomai, Elena Fontana, Dario Di Silvestre, Rosita Rigoni, Genni Enza Marcovecchio, Elena Draghici, Francesca Brambilla, Maria Carmina Castiello, Gloria Delfanti, Despina Moshous, Capucine Picard, Tom Taghon, Victoria Bordon, Ansgar S. Schulz, Catharina Schuetz, Silvia Giliani, Annarosa Soresina, Andrew R. Gennery, Sara Signa, Blachy J. Dávila Saldaña, Ottavia M. Delmonte, Luigi D. Notarangelo, Chaim M. Roifman, Pietro Luigi Poliani, Paolo Uva, Pier Luigi Mauri, Anna Villa, Marita Bosticardo
Publikováno v:
Frontiers in Immunology
FRONTIERS IN IMMUNOLOGY
Frontiers in Immunology, Vol 12 (2021)
FRONTIERS IN IMMUNOLOGY
Frontiers in Immunology, Vol 12 (2021)
Major Histocompatibility Complex (MHC) class II (MHCII) deficiency (MHCII-D), also known as Bare Lymphocyte Syndrome (BLS), is a rare combined immunodeficiency due to mutations in genes regulating expression of MHCII molecules. MHCII deficiency resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b344d5c4229a7857a452efd56f9d37
BTK inhibitors for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): A Systematic Review
Autor:
Michael Stack, Luigi D. Notarangelo, Michail S. Lionakis, Keith Sacco, Riccardo Castagnoli, Alicia A. Livinski
Publikováno v:
Clinical Immunology (Orlando, Fla.)
Research Square
article-version (status) pre
article-version (number) 1
Research Square
article-version (status) pre
article-version (number) 1
ImportanceThe Bruton tyrosine kinase (BTK) regulates B cell and macrophage signaling, development, survival, and activation. BTK inhibition was shown to protect against lethal influenza-induced acute lung injury in mice. Inhibiting BTK has been hypot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49ea09e3d0d2d56cb78e6ccfcfd31477
https://doi.org/10.21203/rs.3.rs-319342/v1
https://doi.org/10.21203/rs.3.rs-319342/v1
Autor:
Annaliesse Blincoe, Alessandro Aiuti, Luigi D. Notarangelo, Michael S. Hershfield, H. Bobby Gaspar, Jennifer M. Puck, Donald B. Kohn, Eyal Grunebaum
Publikováno v:
The Journal of allergy and clinical immunology, vol 143, iss 3
Inherited defects in adenosine deaminase (ADA) cause a subtype of severe combined immunodeficiency (SCID) known as severe combined immune deficiency caused by adenosine deaminase defects (ADA-SCID). Most affected infants can receive a diagnosis while