Zobrazeno 1 - 10
of 10
pro vyhledávání: '"June-Woo Lee"'
Autor:
Ki Ho Hong, June-Woo Lee, Gye Cheol Kwon, Seung-Jung Kee, Hyun Soo Kim, Jaehyeon Lee, Su-Kyung Lee, Hyeon-Nam Do, Ah-Ra Kim, Sung Soon Kim, Jungwon Hyun, Eun-Jee Oh, Younhee Park, Su Hwan Kim, Hyukmin Lee, Sang Hoon Song
Publikováno v:
Annals of Laboratory Medicine
Background Seroprevalence studies of coronavirus disease 2019 (COVID-19) cases, including asymptomatic and past infections, are important to estimate the scale of the disease outbreak and to establish quarantine measures. We evaluated the clinical pe
Autor:
Jung Sik Yoo, Ji-Yeon Hyeon, June-Woo Lee, Ho Sun Son, Sang-Won Lee, Gyung Tae Chung, Hyejin Kim, Youngsil Yoon
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 3, p e0210477 (2019)
PLoS ONE, Vol 14, Iss 3, p e0210477 (2019)
Enterovirus (EV) 71 is the main pathogen associated with hand-foot-mouth disease (HFMD) and can lead to the disease with severe mortality in children. Since 2009, in the Republic of Korea, an outbreak of EV71 C4a infection with neurologic involvement
Autor:
Heeji Lim, Sang-Won Lee, Jung-Ah Lee, June-Woo Lee, Hyun Ju In, Gyung Tae Chung, Jae Keun Chung, Sun Ju Cho, Young Ki Choi, Jung Sik Yoo
Publikováno v:
Vaccine. 36(24)
Coxsackievirus belongs to the Enterovirus genus of the Picornaviridae family and is one of the major pathogens associated with human hand, foot, and mouth disease (HFMD). Historically, outbreaks of HFMD have mainly been caused by enterovirus 71 and c
Autor:
June Woo Lee, Myeong Ho Jung, Won Ho Kim, Bin Gao, Young Ho Suh, Seung Hee Lee, Yeo Kyoung Oh, Hyunjung Lee
Publikováno v:
Cellular Signalling. 19:791-805
We previously demonstrated that chronic high glucose (33.3 mM) induced β-cell dysfunction and apoptosis through glucokinase (GCK) downregulation, but the exact mechanisms involved remain unclear. Here, we show that prolonged exposure of 5-aminoimida
Autor:
Joo Sun Choi, Young Ho Suh, Ji Hyun Song, Myeong Ho Jung, Joo Hyun Lim, Shin Hee Hong, June Woo Lee, Bin Gao, Won Ho Kim
Publikováno v:
Diabetes. 54:2602-2611
Chronic hyperglycemia is toxic to pancreatic β-cells, impairing cellular functioning as observed in type 2 diabetes; however, the mechanism underlying β-cell dysfunction and the resulting apoptosis via glucose toxicity are not fully characterized.
Publikováno v:
Hepatology Research. 26:302-310
The relation between transforming growth factor-beta (TGF-beta) and cyclooxygenase (COX) in hepatoma malignancy is not understood yet. To investigate regulation mechanism of endogenous TGF-beta on hepatoma, we established MH129F mouse hepatoma cell o
Autor:
Ki-Sang Kim, Sang-Gu Yeo, June-Woo Lee, Byung-Hak Kang, Doo-Sung Cheon, Jin-Won Kim, Sun-Hwa Lee, Hoe-Kyu Lee
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 5, p e36656 (2012)
PLoS ONE, Vol 7, Iss 5, p e36656 (2012)
BACKGROUND: Echovirus 30 (Echo30) is one of the most frequently identified human enteroviruses (EVs) causing aseptic meningitis and encephalitis. However the mechanism underlying the pathogenesis of Echo30 infection with significant clinical outcomes
Publikováno v:
Molecules and cells. 30(6)
Mitochondrial dysfunction induces apoptosis of pancreatic β-cells and leads to type 2 diabetes, but the mechanism involved in this process remains unclear. Chronic endoplasmic reticulum (ER) stress plays a role in the apoptosis of pancreatic β-cell
Autor:
Myeong Ho Jung, Kang Yuel Choi, Won Ho Kim, June Woo Lee, Jihyun Song, Eun Hyeon Song, Joo Hyun Lim
Publikováno v:
Cellular signalling. 21(1)
Mitochondrial dysfunction has been considered a critical component in the development of diabetes. In pancreatic beta-cells especially, mitochondrial dysfunction impairs insulin secretion and the eventual apoptosis of beta-cells. The aim of this stud
Publikováno v:
Cellular signalling. 17(12)
IFN-gamma and TNF-alpha are major proinflammatory cytokines implicated in islet beta-cell destruction, which results in type-1 diabetes; however, the underlying mechanism is not clear. Using pancreatic beta-cell line MIN6N8 cells, co-treatment with T