Zobrazeno 1 - 10
of 50
pro vyhledávání: '"John Walker"'
Publikováno v:
Cancer Immunology, Immunotherapy. 69:1423-1436
On-treatment steroids for countering immune checkpoint inhibitor-induced inflammatory responses (irAEs) are a hallmark of cancer immunotherapy. However, the suppressive nature of steroids has raised questions regarding their ability to compromise the
Publikováno v:
European Heart Journal. 41
Background Anthracycline cardiotoxicity has been known for many years but identifying patients most at risk remains imperfect. Conventionally, standard cardiovascular risk factors including biomarkers are included in assessments. Purpose We investiga
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundWe have previously reported that the upregulation of galectin-9 (Gal-9) on CD4+ and CD8+ T cells in HIV patients was associated with impaired T cell effector functions. Gal-9 is a ligand for T cell immunoglobulin and mucin domain-3, and its
Publikováno v:
Vaccines, Vol 9, Iss 1416, p 1416 (2021)
Vaccines
Vaccines; Volume 9; Issue 12; Pages: 1416
Vaccines
Vaccines; Volume 9; Issue 12; Pages: 1416
To investigate whether oral administration of maize-produced S antigen can provide passive immunity to piglets against porcine epidemic diarrhea virus (PEDV), 16 pregnant sows were randomly assigned to one of four treatments: (1) injection of PEDV va
Autor:
Lai Xu, Michael Smylie, Mary M. Hitt, James A. Nieman, John Walker, Guangzhi Zhang, Joydeb Kumar Kundu, Isobel Okoye, Seyedeh Nargess Hosseini, Nutan Srivastava, William L. Turnbull, Hena Mostafa, Dinesh Babu, Khaled Barakat, Justin Shields, Katharine Cheryl Agopsowicz, Frederick G. West, Tae Chul Moon, D. Lorne Tyrrell, Yasser M Tabana, Appan Srinivas Kandadai, Alexandr Belovodskiy, Marawan Ahmed, Shokrollah Elahi, Aravindhan Ganesan, Elena Arutyunova, Michael Houghton, Arno G. Siraki, M. Joanne Lemieux
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-19 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-19 (2019)
Blockade of the programmed cell death 1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction has emerged as a powerful strategy in cancer immunotherapy. Recently, there have been enormous efforts to develop potent PD-1/PD-L1 inhibitors. In parti
Autor:
Nabeela Nathoo, John Walker, Michael Smylie, Rajive Jassal, Jennifer A. McCombe, Grayson Beecher, Dustin Anderson
Publikováno v:
Neurooncol Pract
Immune checkpoint inhibitors such as antibodies to cytotoxic lymphocyte-associated protein 4 (ipilimumab) and programmed cell-death 1 (pembrolizumab, nivolumab) molecules have been used in non-small cell lung cancer, metastatic melanoma, and renal-ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab5076c555ecff7bb0250a63897e0802
https://europepmc.org/articles/PMC6753352/
https://europepmc.org/articles/PMC6753352/
Autor:
John Walker, Andrew Pickford
Publikováno v:
Road Pricing: Technologies, economics and acceptability ISBN: 9781785612053
The emphasis of the chapter is on electronic systems, not cash or paper-based schemes, often described as multi-lane free-flow - there are no toll barriers, and no need for vehicles to stop in order to pay; stopping is undesirable since it results in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ecab5cbc76d5a7af0421eb803db638d
https://doi.org/10.1049/pbtr008e_ch1
https://doi.org/10.1049/pbtr008e_ch1
Publikováno v:
Cancer Research. 79:LB-187
Introduction: SNX-5422 is the orally active prodrug of SNX-2112, a potent, highly selective inhibitor of heat-shock protein 90 (Hsp90) with promising anti-tumor activity in clinical trials. SNX-5422 enhanced anti-PD-1 activity in MC38 murine model. S
Autor:
Meliessa Hennessy, Josh Reed, Vijay Kasturi, Shahneen Sandhu, Giovanni Grignani, Céleste Lebbé, Subramanian Hariharan, John Walker, Steven Hildemann
Publikováno v:
Journal of Clinical Oncology. 36:9537-9537
9537Background: Avelumab is a human anti–PD-L1 IgG1 antibody that showed a favorable efficacy and toxicity profile in pts with mMCC and progressive disease (PD) on or after chemotherapy (CT) in the...
Publikováno v:
International Journal of Peptide and Protein Research. 11:301-304
The amino acid sequence of the first 33 residues of the non-histone chromosomal protein HMG 14 has been determined. The presence of two regions of common sequence between HMG 14 and both the non-histone chromosomal protein HMG 17 and the trout specif