Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jinming Zhang"'
Autor:
Jin-Feng Shi, Huan Gu, Jiaqi Ma, Yali Ren, Yihan Wu, Jinming Zhang, Xi Luo, Zhixing Cao, Chaomei Fu, Jiaxin Li
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-22 (2021)
Journal of Nanobiotechnology
Journal of Nanobiotechnology
Background The toxicity and inefficient delivery of triptolide (TPL) in tumor therapy have greatly limited the clinical application. Thus, we fabricated a CD44-targeting and tumor microenvironment pH/redox-sensitive nanosystem composed of hyaluronic
Autor:
Meisi Lin, Shanshan Qi, Yao He, Ruifeng Luo, Wenbiao Nie, Huiyun Zhong, Xiaoqin Han, Jinming Zhang, Xiulan Pu, Fei Gao, Lingling Dong, Qiyan Chen, Haiting Xu, Chaomei Fu, Fang Liu
Publikováno v:
Biomacromolecules. 22:2754-2767
In this study, we developed an advanced colitis-targeted nanoparticles (NPs)-into-yeast cell wall microparticles (YPs) drug delivery system for ulcerative colitis (UC) therapy. In brief, YPs entrap hyaluronic acid (HA), and polyethylenimine (PEI) mod
Autor:
Jingwen Du, Yingmiao Liu, Yuqing Guan, Jin Zhou, Tao Li, Tao Jiang, Jinming Zhang, Lixiu Wang, Haijiao Jing, Nan Zuo, Jialan Shi, Yueyue Li, Rujuan Xie, Baorong Li, Wenhui Liu, Zengxiang Dong, Jiaqi Jin, Muxin Yu
Publikováno v:
Thrombosis Research. 188:5-16
Patients with pancreatic cancer (PC) are at increased risk of venous thrombosis, but the precise mechanisms of hypercoagulable state in PC remain unclear. We aimed to identify how phosphatidylserine positive (PS+) blood cells (BCs), PS+ microparticle
Publikováno v:
Oncology Letters
Ewing's sarcoma (ES) is the second most common bone tumor among children and adolescents worldwide. However, the genes and signaling pathways involved in ES tumorigenesis and progression remain unclear. The present study used two gene-expression prof
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology
Frontiers in Oncology
ObjectivesPhosphatase and tensin homolog (PTEN) mutation is an indicator of poor prognosis of low-grade and high-grade glioma. This study built a reliable model from multi-parametric magnetic resonance imaging (MRI) for predicting the PTEN mutation s
Autor:
Shaoxi Cai, Yujie Qiao, Hangming Dong, Zhaojin Zeng, Haohua Huang, Weimou Chen, Yuanyuan Liu, Ye Lu, Wenshan Zhong, Jinming Zhang
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology, Vol 12 (2021)
Idiopathic pulmonary fibrosis is a progressive fatal disease characterized by interstitial remodeling, with high lethality and a lack of effective medical therapies. Tetrandrine has been proposed to present anti-fibrotic effects, but the efficacy and
Autor:
George P.H. Leung, Jinming Zhang, Guo-Chun Zhou, Zhuyun Liu, Dekuan Sheng, Jingjing Li, Renkai Li, Simon Ming-Yuen Lee, Xiaoping Wu, Kun Dai
Publikováno v:
Phytomedicine : international journal of phytotherapy and phytopharmacology. 94
Background : The anti-cancer activity of andrographolide (Andro) has been extensively demonstrated in recent years. It is supposed that modifying the chemical structure of Andro can improve its efficacy and reduce its toxicity. Purpose : In this stud
Autor:
Yingmiao Liu, Shaohong Fang, Jingwen Du, Jialan Shi, Ruishuang Ma, Rui Xie, Jinming Zhang, Lixiu Wang, Wujian Zhang, Baorong Li, Zengxiang Dong, Jin Zhou, Xinyi Zhao, Tao Li, Muxin Yu, Tao Jiang, Chunxu Wang
Publikováno v:
Journal of Crohn's and Colitis. 14:240-253
Background and Aims Despite the presence of neutrophil extracellular traps [NETs] in inflamed colon having been confirmed, the role of NETs, especially the circulating NETs, in the progression and thrombotic tendency of inflammatory bowel disease [IB
Autor:
Jin Zhou, Yingmiao Liu, Yueyue Li, Peng Zhou, Xiaojing Chen, Jinming Zhang, Lixiu Wang, Yue Zhang, Haijiao Jing, Jialan Shi, Chunxu Wang, Jingwen Du, Muxin Yu, Baorong Li, Shaohong Fang, Valerie A. Novakovic, Yufeng Wang, Yiming Feng, Zengxiang Dong
Publikováno v:
EBioMedicine, Vol 60, Iss, Pp 102992-(2020)
EBioMedicine
EBioMedicine
Background The role of vascular endothelium in acute promyelocytic leukaemia (APL) remains unknown. We aimed to investigate the mechanisms by which APL cells interact with endothelial cells (ECs) and to further explore how the endothelium affects ble
Autor:
Shaohong Fang, Mengqi Xiang, Langjiao Liu, Cong Zhang, Shuoqi Zhang, Xiaojing Chen, Chengyue Wang, Jinming Zhang, Jingwen Du, Xiaoming Wu, Yueyue Li, Chunli Wang, Jialan Shi, Huan Liu, Mengdi Li
Publikováno v:
Clinics and Research in Hepatology and Gastroenterology. 46:101697
BACKGROUND Nonalcoholic steatohepatitis (NASH) patients are at a high risk of developing venous thromboembolism, with a high rate of morbidity and mortality. The role of neutrophil extracellular traps (NETs) in procoagulant activity (PCA) in patients