Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Jee H. Jung"'
Autor:
Dan-Dan Li, Dong-Hao Bai, Jee H. Jung, Bin Xiao, Ying Wang, Na Zhao, Shang-Wu Jin, Li-Dong Sun, Eun La Kim
Publikováno v:
Biomolecules & Therapeutics
In a search for effective PPAR-γ agonists, 110 clinical drugs were screened via molecular docking, and 9 drugs, including parecoxib, were selected for subsequent biological evaluation. Molecular docking of parecoxib to the ligand-binding domain of P
Publikováno v:
Bioorganic chemistry. 96
In our previous study, a PPAR-γ agonist (+)-(R,E)-6a1 was elaborated as an anti-inflammatory lead. However, in silico analysis showed that (+)-(R,E)-6a1 lacks key hydrogen bonding with Tyr473 of PPAR-γ LBD (ligand binding domain). To facilitate add
Publikováno v:
Biomolecules & Therapeutics
4-Hydroxy-2-(4-hydroxyphenethyl)isoindoline-1,3-dione (PD1) is a synthetic phthalimide derivative of a marine compound. PD1 has peroxisome proliferator-activated receptor (PPAR) γ agonistic and anti-inflammatory effects. This study aimed to investig
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:4970-4974
Viriditoxin is a fungal secondary metabolite of the fungus Paecilomyces variotii derived from the inner tissues of the giant jellyfish Nemopilema nomurai. Viriditoxin exhibits antibacterial activity against Streptococcus iniae and Streptococcus parau
Autor:
Saeromi Kang, Dong-Soon Im, Jung-Min Kim, Jee H. Jung, Young-Geun Lee, Jung-Min Lee, Kyoung-Pil Lee, Soo-Jin Park, Hyung Ryong Moon, Young-Whan Choi
Publikováno v:
Journal of Ethnopharmacology. 178:17-24
Ethnopharmacological relevance The giant butterbur Petasites japonicus is used to treat asthma and allergic diseases in traditional Korean, Japanese, and Chinese medicine. Aim of the study To elucidate the anti-allergic effect of Petasites genus, we
Autor:
Hyung Ryong Moon, Eunok Im, Sujin Son, Yunna Lee, Jieun Choo, Jee H. Jung, Charalabos Pothoulakis, Xin-jia Yan, Seong Jin Kim, Tae Hwan Noh
Publikováno v:
The Journal of biological chemistry, vol 290, iss 42
Choo, J; Lee, Y; Yan, XJ; Noh, TH; Kim, SJ; Son, S; et al.(2015). A Novel Peroxisome Proliferator-activated Receptor (PPAR)y Agonist 2-Hydroxyethyl 5-chloro-4, 5-didehydrojasmonate Exerts Anti-Inflammatory Effects in Colitis. Journal of Biological Chemistry, 290(42), 25609-25619. doi: 10.1074/jbc.M115.673046. UCLA: Retrieved from: http://www.escholarship.org/uc/item/3038w8kf
Choo, J; Lee, Y; Yan, XJ; Noh, TH; Kim, SJ; Son, S; et al.(2015). A Novel Peroxisome Proliferator-activated Receptor (PPAR)y Agonist 2-Hydroxyethyl 5-chloro-4, 5-didehydrojasmonate Exerts Anti-Inflammatory Effects in Colitis. Journal of Biological Chemistry, 290(42), 25609-25619. doi: 10.1074/jbc.M115.673046. UCLA: Retrieved from: http://www.escholarship.org/uc/item/3038w8kf
© 2015 by The American Society for Biochemistry and Molecular Biology, Inc. Inflammatory bowel disease (IBD) is a chronic inflammatory disease with increasing incidence and prevalence worldwide. Here we investigated the newly synthesized jasmonate a
Autor:
Zhiran Ju, Jiafu Cao, Young-Suk Jung, Mingzhi Su, Eun La Kim, Chang-Hao Zhao, Jee H. Jung, Dan-Dan Li
Publikováno v:
Marine Drugs
Volume 18
Issue 9
Marine Drugs, Vol 18, Iss 445, p 445 (2020)
Volume 18
Issue 9
Marine Drugs, Vol 18, Iss 445, p 445 (2020)
Microtubules play a crucial role in mitosis and are attractive targets for cancer therapy. Recently, we isolated viriditoxin, a cytotoxic and antibacterial compound, from a marine fungus Paecilomyces variotii. Viriditoxin has been reported to inhibit
Autor:
Yunna Lee, Jee H. Jung, Su Jin Kim, Sujin Son, Eunok Im, Do Hyun Kim, Min Jae Kim, Yunjin Jung, Gwangbeom Heo, Jieun Choo, Wooseong Kim, Tae Hwan Noh, Hae Young Chung, Hyung Ryong Moon
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 9, Pp 1-17 (2018)
Cell Death and Disease, Vol 9, Iss 9, Pp 1-17 (2018)
Many stress conditions including chemotherapy treatment is known to activate Src and under certain condition Src can induce the apoptotic signal via c-Jun N-terminal kinase (JNK) activation. Here we report that the newly synthesized β-phenylacrylic
Publikováno v:
Marine Drugs, Vol 15, Iss 1, p 7 (2017)
Marine Drugs; Volume 15; Issue 1; Pages: 7
MARINE DRUGS(15): 1
Marine Drugs
Marine Drugs; Volume 15; Issue 1; Pages: 7
MARINE DRUGS(15): 1
Marine Drugs
Previously, the authors found that 4-hydroxy-2-(4-hydroxyphenethyl) isoindoline-1,3-dione (PD1) (a phthalimide analogue) bound to and activated peroxisome proliferator-activated receptor-gamma (PPAR-gamma). Since PPAR-gamma suppresses inflammatory re
Autor:
Huayue Li, Jaewon Lee, Eun La Kim, Eun-Hee Kim, Hyung Sik Kim, Haibo Wang, Mingzhi Su, Jee H. Jung
Publikováno v:
Bioorganicmedicinal chemistry. 24(13)
Two new cystine knot peptides, asteropsins F (ASPF) and G (ASPG), were isolated from the marine sponge Asteropus sp. ASPF and ASPG are composed of 33 and 32 amino acids, respectively, and contain six cysteines which are involved in three disulfide bo