Zobrazeno 1 - 10
of 18
pro vyhledávání: '"J. Nemeth"'
Autor:
Kelvin P. Lee, G. Aaron Holling, Scott H. Olejniczak, Shivana M. Lightman, Louise M. Carlson, Mackenzie M. Honikel, Jennifer Peresie, Colin Chavel, Michael J. Nemeth
Publikováno v:
Immunity
Humoral immunity is essential for protection against pathogens, emphasized by the prevention of 2-3 million deaths worldwide annually by childhood immunizations. Long-term protective immunity is dependent on the continual production of neutralizing a
Autor:
Christopher W. L. Dougher, Alexander Buffone, Paul N. Bogner, Mehrab Nasirikenari, Eric E Irons, Michael J. Nemeth, Joseph T.Y. Lau
Publikováno v:
Journal of Leukocyte Biology. 102:507-516
Responding to systemic demands in producing and replenishing end-effector blood cells is predicated on the appropriate delivery and interpretation of extrinsic signals to the HSPCs. The data presented herein implicate the systemic, extracellular form
Autor:
Beata Lelesz, G. K. Tóth, Réka Sári, László Drimba, Csaba Hegedűs, J. Nemeth, Barna Peitl, Zoltán Szilvássy
Publikováno v:
Journal of Radioanalytical and Nuclear Chemistry. 299:157-164
The gut hormone glucagon-like peptide-1 (GLP-1) is derived from the transcription product of the proglucagon gene in the intestinal L cells. The known physiological functions of this peptide include: increases insulin and decreases glucagon secretion
Publikováno v:
Journal of Radioanalytical and Nuclear Chemistry. 251:129-133
The iodination and separation of various diagnostically and/or experimentally important peptides including (Tyr1)-somatostatin-14, rat Tyr-a-calcitonin gene-related peptide (23-37), motilin and vasoactive intestinal peptide, furthermore bovine serum
Publikováno v:
The Journal of biological chemistry. 289(22)
Tyrosine kinase inhibitors such as imatinib can effectively target the BCR-ABL oncoprotein in a majority of patients with chronic myeloid leukemia (CML). Unfortunately, some patients are resistant primarily to imatinib and others develop drug resista
Publikováno v:
Diseases of the Colon & Rectum. 44:1682-1688
Adjuvant chemotherapy is effective for node-positive colon cancer patients. In node-negative patients, it could be justified in high-risk patients. The purpose of this study was to determine clinical and pathological findings associated with tumor re
Autor:
Marie-Françoise Heymann, J Nemeth, J. Le Borgne, J Visset, S Cordel, Madeleine Joubert, J. C. Le Neel, B Ranc, Arnaud Murat, M. F. Le Bodic, A Hamy
Publikováno v:
Histopathology. 36:421-432
Aims To study the clinical outcome of 82 cases of pancreatic neuroendocrine tumours classified according to the recent histological and prognostic classification of Capella. Methods and results Eighty-two surgical cases of pancreatic neuroendocrine t
Publikováno v:
Gut. 36:522-527
Gastric body mucosal proliferation was quantified and localised under conditions of increased gastrin drive using a variety of techniques. Rats were given omeprazole 400 mumol/kg/day by gavage and after 30 days mean serum gastrin rose 11-fold (p < 0.
Publikováno v:
Gut. 34:90-95
The possible production of gastrin by colorectal carcinomas has been studied. Extracts of 44 tumours and adjacent macroscopically normal tissue were examined in radioimmunoassay using the following antibodies: (i) L289 raised to a C-terminal fragment
Publikováno v:
European Journal of Clinical Investigation. 22:638-644
The main form of gastrin in antral mucosa, the amidated heptadecapeptide G17, is generated from an inactive precursor, progastrin, by steps involving endopeptidase cleavage and amidation. Gastrin cells are normally inhibited by gastric acid and in th