Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Hong-Yuan Chen"'
Publikováno v:
The Analyst. 146:1548-1551
Drop-on-demand microkits with a diameter of ∼20 μm are used to measure the activity of acetylcholinesterase (AChE) in a brain slice with single-cell resolution. The relative standard deviation from 25 cellular regions reached 73.3% exhibiting the
Publikováno v:
ACS Applied Nano Materials. 3:11489-11496
A ZnAgInS quantum dot (QD)-decorated BiOI microsphere (BiOI-ZAIS) heterostructure was first proposed and successfully employed for sensitive cathodic photoelectrochemical (PEC) bioanalysis. Specifi...
Autor:
Takanori Suzuki, Hong-Yuan Chen, Yuqi Wang, Wenhui Zeng, Deju Ye, Yuxuan Hu, Yusuke Ishigaki, Yidan Sun, Takashi Harimoto, Luyan Wu
Publikováno v:
Angewandte Chemie. 134
Accurate detection of hepatic hydrogen sulfide (H 2 S) to monitor H 2 S-related enzymes' activity is critical for acute hepatitis diagnosis, but remains a challenge due to the dynamic and transient nature of H 2 S. Here, we report a H 2 S-activatable
Publikováno v:
Journal of Endocrinological Investigation. 43:1309-1316
The aim was to examine changes in the bone-derived hormone lipocalin 2 (LCN2) levels in patients with active acromegaly and to investigate the potential roles of LCN2 and osteocalcin in glucose metabolism. We recruited 50 consecutive acromegalic pati
Publikováno v:
Analytical Chemistry. 91:15988-15992
MicroRNAs (miRNAs) play key roles in many serious diseases, such as cancer. As a consequence, miRNAs are of great interest as biomarkers in clinical diagnostics. Simple, fast, selective, and sensitive detection of miRNAs, however, is challenged by th
Publikováno v:
Analytica Chimica Acta. 1079:146-152
A novel versatile locked nucleic acid modified molecular beacon probe (LNA-MB) was developed for imaging intracellular precursor miRNAs (pre-miRNAs) and disturbing Dicer-mediated cleavage process. The target recognition reaction between the smart pro
Publikováno v:
Analytical chemistry. 93(43)
The chemical reaction in a confined space is known to be accelerated due to a high collision probability; however, the study of this confinement effect in a supersmall space down to femtoliter (fL) is seldom reported. Here, an adjustable volume [from
Autor:
Yao Liu, Tiezheng Pan, Kefan Wang, Yuqin Wang, Shuanghong Yan, Liying Wang, Shanyu Zhang, Xiaoyu Du, Wendong Jia, Panke Zhang, Hong‐Yuan Chen, Shuo Huang
Publikováno v:
Angewandte Chemie (International ed. in English). 60(44)
Recent developments concerning large protein nanopores suggest a new approach to structure profiling of native folded proteins. In this work, the large vestibule of Mycobacterium smegmatis porin A (MspA) and calmodulin (CaM), a Ca2+ -binding protein,
Autor:
Yuqin Wang, Panke Zhang, Xiaoyu Du, Shuanghong Yan, Jinyue Zhang, Liying Wang, Hong-Yuan Chen, Yu Wang, Fubo Ma, Shanyu Zhang, Shuo Huang
Publikováno v:
ACS sensors. 6(8)
Cisplatin, which selectively binds to N7 atoms of purines to inhibit normal replication and transcription, is a widely applied chemotherapeutic drug in the treatment of cancer. Though direct identification of cisplatin lesions on DNA is of great sign
Publikováno v:
Electrochemistry Communications, Vol 98, Iss, Pp 33-37 (2019)
An ultrasensitive and highly selective electrochemiluminescence (ECL) immunosensor is proposed for the detection of prostate specific antigen (PSA) based on multiple amplification via glucose oxidase (GOx) and platinum nanoparticles (Pt NPs) conjugat