Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Herbert J. Zeh"'
Autor:
Michael A. Belsky, Patti Petrosko, Michael J. Becich, Steven A. Ahrendt, Matthew P. Holtzman, William A. LaFramboise, Haroon A. Choudry, Reetesh K. Pai, James F. Pingpank, Peter G. Howard, David L. Bartlett, Rajiv Dhir, Herbert J. Zeh, Apoorv Dhir
Publikováno v:
Modern Pathology. 32:1197-1209
DNA was obtained from matching micro-dissected, primary tumor cells, paired metastases, and peripheral blood mononuclear cells (germline) from patients with appendiceal mucinous neoplasms. We compared specimens from patient cohorts comprising low-gra
Autor:
Todd A. Aguilera, Rolf A. Brekken, Mitchell S. von Itzstein, Michael Burke, Muhammad Shaalan Beg, Herbert J. Zeh
Publikováno v:
Target Oncol
Pancreatic cancer is expected to become the second leading cause of cancer-related death within the next few years. Current therapeutic strategies have limited effectiveness and therefore there is an urgency to develop novel effective therapies. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5229bceeffffd2090dc019c75bf314fb
https://europepmc.org/articles/PMC7583676/
https://europepmc.org/articles/PMC7583676/
Autor:
Daolin Tang, Ling Zeng, Daniel J. Klionsky, Borong Zhou, Shan Zhu, Jianxin Jiang, Timothy R. Billiar, Guido Kroemer, Haichao Wang, Jiao Liu, Herbert J. Zeh, Rui Kang
Publikováno v:
Autophagy
Sepsis is the most common cause of death for patients in intensive care worldwide due to a dysregulated host response to infection. Here, we investigate the role of sequestosome-1 (SQSTM1/p62), an autophagy receptor that functions as a regulator of i
Autor:
Rui Kang, Herbert J. Zeh, Timothy R. Billiar, Ruochan Chen, Xue Gong Fan, Haichao Wang, Shan Zhu, Daolin Tang, Michael T. Lotze
Publikováno v:
Hepatology. 67:1823-1841
Emerging studies have suggested that the Hippo pathway is involved in the tumorigenesis of hepatocellular carcinoma (HCC). However, the key regulator of the Hippo pathway in liver tumor metabolic reprogramming remains elusive. Here, we provide eviden
Autor:
Matthew P. Holtzman, Melissa E. Hogg, J. Wallis Marsh, David L. Bartlett, James F. Pingpank, Mashaal Dhir, Amer H. Zureikat, David A. Geller, M. Haroon A. Choudry, Herbert J. Zeh, Heather L. Jones, Mazen S. Zenati, Nathan Bahary, Allan Tsung
Publikováno v:
Annals of Surgical Oncology. 25:550-557
In the era of modern effective systemic chemotherapy, the comparative effectiveness of hepatic artery infusion (HAI) versus selective internal radiation therapy (yttrium-90 [Y90]) for pretreated patients with isolated unresectable colorectal liver me
Autor:
Kenneth K. Lee, James W. Marsh, Herbert J. Zeh, Melissa E. Hogg, Randall E. Brand, Georgios I. Papachristou, Kevin McGrath, David L. Bartlett, Marina N. Nikiforova, Adam Slivka, Sara E. Monaco, Allan Tsung, Kenneth E. Fasanella, James F. Pingpank, Abigail I. Wald, Anil K. Dasyam, Jennifer Chennat, Aatur D. Singhi, Amer H. Zureikat, N. Paul Ohori, Asif Khalid
Publikováno v:
Gut
ObjectiveDNA-based testing of pancreatic cyst fluid (PCF) is a useful adjunct to the evaluation of pancreatic cysts (PCs). Mutations in KRAS/GNAS are highly specific for intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms (
Publikováno v:
Autophagy. 14:2173-2175
Ferroptosis is a form of regulated cell death triggered by lipid peroxidation after inhibition of the cystine/glutamate antiporter system X(c)(−). However, key regulators of system X(c)(−) activity in ferroptosis remain undefined. Here, we show t
Autor:
Yixiang Zhen, Xiao Zhong, Ruochan Chen, Timothy R. Billiar, Xue Gong Fan, Haichao Wang, Daolin Tang, Yongmin Fu, Yan Huang, Pinhua Pan, Yangchun Xie, Rui Kang, Herbert J. Zeh, David L. Bartlett, Michael T. Lotze
Publikováno v:
Oncotarget
// Ruochan Chen 1, 2 , Yangchun Xie 2 , Xiao Zhong 1 , Yongmin Fu 1 , Yan Huang 1 , Yixiang Zhen 1 , Pinhua Pan 3 , Haichao Wang 4 , David L. Bartlett 2 , Timothy R. Billiar 2 , Michael T. Lotze 2 , Herbert J. Zeh, III 2 , Xue-Gong Fan 1 , Daolin Tan
Autor:
Michael T. Lotze, Mark A. Ross, Georgios I. Papachristou, Patricia Loughran, Aatur D. Singhi, Brian A. Boone, Pedram Paragomi, Pranav Murthy, Amer H. Zureikat, David C. Whitcomb, Herbert J. Zeh
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
Background: Neutrophil extracellular traps (NETs) are generated when activated neutrophils, driven by PAD4, release their DNA, histones, HMGB1, and other intracellular granule components. NETs play a role in acute pancreatitis, worsening pancreatic i
Autor:
Ling Zeng, Ruochan Chen, Jiao Liu, Haichao Wang, Jianxin Jiang, Herbert J. Zeh, Shan Zhu, Daolin Tang, Rui Kang, Guido Kroemer, Timothy R. Billiar
Publikováno v:
Science Advances
Targeting immunometabolism is a strategy to prevent infection-mediated septic death.
The ability of cytosolic lipopolysaccharide (LPS) to activate caspase-11–dependent nonclassical inflammasome is intricately controlled to avoid excessive infl
The ability of cytosolic lipopolysaccharide (LPS) to activate caspase-11–dependent nonclassical inflammasome is intricately controlled to avoid excessive infl