Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Genny del Zotto"'
Autor:
Lorenzo Moretta, Chiara Dentone, Francesca Antonini, Giorgio Gribaudo, Andrea Pelosi, Letizia Muccio, Genny Del Zotto, Maria Libera Ascierto, Mariella Della Chiesa, Francesca Moretta, Andrea De Maria, Giovanni Cenderello, Laura Ambra Nicolini, Alessandro Moretta, Anna Luganini, Federica Bozzano
Publikováno v:
Journal of Allergy and Clinical Immunology. 147:2343-2357
Background There is limited knowledge on the origin and development from CD34+ precursors of the ample spectrum of human natural killer (NK) cells, particularly of specialized NK subsets. Objective This study sought to characterize the NK-cell progen
Autor:
Fatma Betul Oktelik, Qian Chen, Metin Yusuf Gelmez, Mehdi Benamar, Ayca Kiykim, Ye Cui, Jason Jun Hung Fong, Achille Broggi, Jonathan Z. Li, Sreya Ghosh, Peggy S. Lai, Hani Harb, Murat Kose, Esin Aktas Cetin, Paola Contini, Jason W. Griffith, Ivan Zanoni, Talal A. Chatila, Lorenzo Berra, Elena Crestani, Ziwei Wang, Novalia Pishesha, Klaus Schmitz-Abe, Louis-Marie Charbonnier, Raffaele De Palma, Günnur Deniz, Gilberto Filaci, Emmanuel Stephen-Victor, Stephen C. Kolifrath, Xu G. Yu, Luca Marri, Hidde L. Ploegh, Genny Del Zotto
Publikováno v:
Immunity
Immunity, 2021, 54 (6), pp.1186-1199.e7. ⟨10.1016/j.immuni.2021.04.002⟩
Immunity, 2021, 54 (6), pp.1186-1199.e7. ⟨10.1016/j.immuni.2021.04.002⟩
A cardinal feature of COVID-19 is lung inflammation and respiratory failure. In a prospective multi-country cohort of COVID-19 patients, we found that increased Notch4 expression on circulating regulatory T (Treg) cells was associated with disease se
Autor:
Silvia Pesce, Marco Greppi, Francesco Grossi, Genny Del Zotto, Lorenzo Moretta, Simona Sivori, Carlo Genova, Emanuela Marcenaro
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
The identification of inhibitory NK cell receptors specific for HLA-I molecules (KIRs and NKG2A) provided the molecular basis for clarifying the mechanism by which NK cells kill transformed cells while sparing normal cells. The direct interactions be
Autor:
Giovanni Candiano, Massimo Vitale, Alessandro Moretta, Lorenzo Moretta, Maurizio Bruschi, Alessandra Barbuto, Genny Del Zotto, Claudia Cantoni, Cristina Bottino, Silvia Gaggero, Monica Parodi, Chiara Lavarello, Laura Santucci, Carola Prato, Andrea Petretto
Publikováno v:
OncoImmunology, Vol 7, Iss 9 (2018)
The release of soluble ligands of activating Natural Killer (NK) cell receptors may represent a regulatory mechanism of NK cell function both in physiologic and in pathologic conditions. Here, we identified the extracellular matrix protein Nidogen-1
Autor:
Loris Zamai, Stefano Papa, Francesca Luchetti, Genny Del Zotto, Barbara Canonico, Flavia Buccella, Laura Galeotti
Cytotoxic functions and susceptibility to apoptosis are crucial aspects of NK cells suitable to counter cancer after infusion in oncologic patients. To test the feasibility and the usefulness of infusing in vitro generated NK cells, these two feature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca5d4314eca0dfa24f751400e8a7ee5
https://hdl.handle.net/11576/2512016
https://hdl.handle.net/11576/2512016
Autor:
Stefano Papa, Loris Zamai, Barbara Canonico, Laura Galeotti, Prisco Mirandola, Genny Del Zotto
Publikováno v:
Cytometry. Part A : the journal of the International Society for Analytical Cytology. 75(11)
CD56(bright) natural killer (NK) cells, generated in vitro from CD34+ hematopoietic progenitor cells, were characterized after a 30-day culture with flt3 ligand plus IL-15. Virtually, all CD56(bright) cells expressed CD117, CD25, natural cytotoxicity