Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Ena Wang"'
Autor:
Dennis Fisher, Eren Demirhan, Srinand Ponnathapura Nandakumar, Gregory J. Opiteck, Xiangdong Zhou, Sattva S. Neelapu, Sacha Leandra Prashad, Michael Tees, Rajneesh Nath, David B. Miklos, Parameswaran Hari, Ena Wang, Frederick L. Locke, Sham Mailankody
Publikováno v:
Journal of Clinical Oncology. 39:2527-2527
2527 Background: Allogeneic chimeric antigen receptor (CAR) T cell therapy holds promise in addressing logistical/manufacturing challenges of autologous CAR T cell therapy. ALLO-501 (anti-CD19; uses Cellectis technologies) and ALLO-715 (anti-BCMA) ar
Autor:
Wei Jiang, David F. Stroncek, Zejun Zhou, Zihai Li, Ena Wang, Zhenwu Luo, Maria Anna Julia Westerink, Lisa Martin, Shenghui Qin, Quan Zhen Li, Hui Liu, Ping Jin, Xueling Wu, Min Li, Lumin Zhang, Zhuang Wan, Yongxia Wu, Sonya L. Heath, Zhefeng Meng, Alexander V. Alekseyenko, Elizabeth Ogunrinde, Stephanie Warth
Publikováno v:
Microbiome
Microbiome, Vol 7, Iss 1, Pp 1-16 (2019)
Microbiome, Vol 7, Iss 1, Pp 1-16 (2019)
Background Increased autoreactive antibodies have been reported in HIV disease; however, the mechanism accounting for autoantibody induction in HIV remains unknown. Results Herein, we show that seasonal influenza vaccination induces autoantibody prod
Autor:
Daniel J. Powell, Lana E. Kandalaft, Renee Frank, Thomas Garrabrant, Priyanka Duttagupta, Hongzhe Li, Denarda Dangaj, Davide Bedognetti, Ian S. Hagemann, George Coukos, Emese Zsiros, Ena Wang, Michael Feldman, Janos L. Tanyi, Francesco M. Marincola, Carl H. June, Lin Zhang, Bruce L. Levine
Publikováno v:
Clinical Cancer Research, vol. 21, no. 12, pp. 2840-2850
Purpose: Chemokines are implicated in T-cell trafficking. We mapped the chemokine landscape in advanced stage ovarian cancer and characterized the expression of cognate receptors in autologous dendritic cell (DC)–vaccine primed T cells in the conte
Autor:
Craig L. Slingluff, Yongde Bao, Donna H. Deacon, Walter C. Olson, Ileana S. Mauldin, Ena Wang
Publikováno v:
International Journal of Cancer. 137:1386-1396
Clinical approaches to treat advanced melanoma include immune therapies, whose benefits depend on tumor-reactive T-cell infiltration of metastases. However, most tumors lack significant immune infiltration prior to therapy. Selected chemokines promot
Autor:
Douglas C. Palmer, John S. Tsang, Suresh Cuddapah, Christopher A. Klebanoff, Ena Wang, Joseph G. Crompton, Yun Ji, Manikandan Narayanan, Luca Gattinoni, Rahul Roychoudhuri, Keji Zhao, Francesco M. Marincola, Shashank J. Patel, Madhusudhanan Sukumar, Weiqun Peng, Wenjing Yang, Nicholas P. Restifo
Publikováno v:
Cellular and Molecular Immunology
To better elucidate epigenetic mechanisms that correlate with the dynamic gene expression program observed upon T-cell differentiation, we investigated the genomic landscape of histone modifications in naive and memory CD8(+) T cells. Using a ChIP-Se
Autor:
José Medina-Echeverz, Michael P. Manns, Jonathan M. Weiss, Veena Kapoor, Jay A. Berzofsky, Francesco M. Marincola, Robert H. Wiltrout, Jaba Gamrekelashvili, Nga V. Hawk, Firouzeh Korangy, Ena Wang, Tamar Kapanadze, Masaki Terabe, Tim F. Greten
Publikováno v:
European Journal of Immunology. 45:1148-1158
Immunosuppressive CD11b(+) Gr-1(+) myeloid-derived suppressor cells (MDSCs) accumulate in the livers of tumor-bearing (TB) mice. We studied hepatic MDSCs in two murine models of immune-mediated hepatitis. Unexpectedly, treatment of TB mice with Conca
Autor:
M K Al-Kowari, Dhanya Kizhakayil, Lotfi Chouchane, A Haoudi, A Ismail Chouchane, Pu Li, George Kulik, Ena Wang, M A Al-Muftah, Konduru S Sastry, Francesco M. Marincola
Publikováno v:
Cell Death & Differentiation. 21:1936-1949
Emerging evidence suggests that the resistance of cancer stem cells (CSC) to many conventional therapies is one of the major limiting factors of cancer therapy efficacy. Identification of mechanisms responsible for survival and self-renewal of CSC wi
Autor:
Fang Yin, Sawa Ito, Francesco M. Marincola, Alexandros Spyridonidis, Ena Wang, Sid P. Kerkar, Dhanalakshmi Chinnasamy, Pawel Muranski, Gerrit Weber, J. Joseph Melenhorst, Nancy F. Hensel, Neima Hadi, Austin John Barrett
Publikováno v:
Immunology. 143:96-108
A growing body of evidence suggests that inflammatory cytokines have a dualistic role in immunity. In this study, we sought to determine the direct effects of interferon-γ (IFN-γ) on the differentiation and maturation of human peripheral blood mono
Autor:
Hayato Takahashi, Davide Bedognetti, Kazuhiko Igarashi, Kambiz Mousavi, Yuka Kanno, Vittorio Sartorelli, David Clever, Mahadev Rao, Golnaz Vahedi, Kiyoshi Hirahara, Juan Rivera, Francesco M. Marincola, Atsushi Nakamura, Akihiko Muto, Hossein Zare, Rahul Roychoudhuri, Joseph G. Crompton, George A. Punkosdy, Christopher A. Klebanoff, Michael Bonelli, John J. O'Shea, Ena Wang, Hui Liu, Giuseppe Sciumè, Zhiya Yu, Pawel Muranski, Luca Gattinoni, Nicholas P. Restifo, Victoria Hoffmann, Barbara Dema
Publikováno v:
Nature
Diverse autoimmune and allergic diseases are associated with polymorphisms in a locus encoding the transcription factor BACH2; here, BACH2 is shown to be a broad regulator of immune activation that stabilizes the differentiation of Treg cells by repr