Zobrazeno 1 - 10
of 18
pro vyhledávání: '"E Race"'
Autor:
Richard E. Race, Kimberly Meade-White, Don Gardner, Kent D. Barbian, Brent Race, Lara M. Taubner, Cynthia Favara, Stephen F. Porcella
Publikováno v:
Emerging Infectious Diseases, Vol 15, Iss 2, Pp 207-215 (2009)
Emerging Infectious Diseases
Emerging Infectious Diseases
Characteristics correlated better with host factors than with agent strain.
Transmissible spongiform encephalopathy (TSE) diseases are known to cross species barriers, but the pathologic and biochemical changes that occur during transmission are
Transmissible spongiform encephalopathy (TSE) diseases are known to cross species barriers, but the pathologic and biochemical changes that occur during transmission are
Autor:
Emily A. Olsen, David A. Kocisko, Kil Sun Lee, Kevin M. Arnold, Nadine Bertholet, Jean-Marc Juteau, Byron Caughey, Andrew Vaillant, Richard E. Race
Publikováno v:
Antimicrobial Agents and Chemotherapy. 50:1034-1044
Although transmissible spongiform encephalopathies (TSEs) are incurable, a key therapeutic approach is prevention of conversion of the normal, protease-sensitive form of prion protein (PrP-sen) to the disease-specific protease-resistant form of prion
Publikováno v:
The American Journal of Pathology. 165:2055-2067
Prion protein (PrP) is expressed in many tissues and is required for susceptibility to scrapie and other prion diseases. To investigate the role of PrP expression in different cell types on pathology in retina and brain after scrapie infection, we ex
Autor:
Richard F. Marsh, Richard E. Race, Allen L. Jenny, Richard Rubenstein, William D. Taylor, Janice M. Miller
Publikováno v:
Journal of Veterinary Diagnostic Investigation. 5:309-316
Prion protein (PrP), which is involved in the pathogenesis of scrapie, occurs in 2 forms. The form extracted from scrapie brain is protease resistant (PrP-res), whereas PrP from normal brain is protease sensitive (PrP-sen). This study examined whethe
Autor:
Richard E. Race, Marshall E. Bloom, Larry C. Ewalt, W. J. Hadlow, R. K. Bergman, Donald L. Lodmell
Publikováno v:
Experimental Biology and Medicine. 195:75-78
The phagocytic function of the mononuclear phagocytic system (MPS) in normal sapphire mink and in sapphire mink affected with experimental Aleutian disease was compared. Clearance from blood of carbon particles or ′251-labeledm icroaggregated human
Publikováno v:
Journal of Virology. 67:6270-6272
Congo red inhibits the accumulation of protease-resistant PrP in scrapie-infected mouse neuroblastoma cells. Here we show that Congo red also inhibits the replication of scrapie infectivity in these cells. This observation is consistent with the idea
Publikováno v:
The Journal of infectious diseases. 183(2)
Transmissible spongiform encephalopathies (TSEs) are initiated by a novel kind of agent that produces characteristic degenerative changes in the brain without a detectable systemic inflammatory response or serological changes. A murine scrapie model
Publikováno v:
Biochemical and biophysical research communications. 255(2)
The cloned organic anion transporters from rat, mouse, and winter flounder (rOAT1, mOAT1, fROAT) mediate the coupled exchange of alpha-ketoglutarate with multiple organic anions, including p-aminohippurate (PAH). We have isolated two novel gene produ
Publikováno v:
The Journal of infectious diseases. 178(4)
Probable transmission of bovine spongiform encephalopathy to humans has focused intense interest on all of the transmissible spongiform encephalopathies (TSEs) and how they spread. In all TSEs, an abnormal disease-associated, proteinase K-resistant p
Autor:
Richard E. Race, Darwin Ernst
Publikováno v:
The Journal of general virology. 73
The sequential accumulation of the protease-resistant form of the endogenous prion protein (PrP-res) was compared to levels of scrapie infectivity in the spleen and brain of scrapie-infected mice at various times after inoculation. In mouse spleen Pr