Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Daniel S. Mansur"'
Neuraminidase inhibitors rewire neutrophil function in vivo in murine sepsis and ex vivo in COVID-19
Autor:
Rodrigo de Oliveira Formiga, Flávia C. Amaral, Camila F. Souza, Daniel A. G. B. Mendes, Carlos W. S. Wanderley, Cristina B. Lorenzini, Adara A. Santos, Juliana Antônia, Lucas F. Faria, Caio C. Natale, Nicholas M. Paula, Priscila C. S. Silva, Fernanda R. Fonseca, Luan Aires, Nicoli Heck, Márick R. Starick, Celso M. Queiroz-Junior, Felipe R. S. Santos, Filipe R. O. de Souza, Vivian V. Costa, Shana P. C. Barroso, Alexandre Morrot, Johan Van Weyenbergh, Regina Sordi, Frederico Alisson-Silva, Fernando Q. Cunha, Edroaldo L. Rocha, Sylvie Chollet-Martin, Maria Margarita Hurtado-Nedelec, Clémence Martin, Pierre-Régis Burgel, Daniel S. Mansur, Rosemeri Maurici, Matthew S. Macauley, André Báfica, Véronique Witko-Sarsat, Fernando Spiller
Publikováno v:
bioRxiv
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Neutrophil overstimulation plays a crucial role in tissue damage during severe infections. Neuraminidase (NEU)-mediated cleavage of surface sialic acid has been demonstrated to regulate leukocyte responses. Here, we report that antiviral NEU inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7e80654188358ad8cc60996af3801d8
https://europepmc.org/articles/PMC9641843/
https://europepmc.org/articles/PMC9641843/
Autor:
Annika Jasper, Teodoro Fajardo, Harriet V Mears, Skye Storrie, Trevor R. Sweeney, Daniel S. Mansur, Thomas J Sanford
Publikováno v:
Nucleic Acids Research
Flaviviruses, including dengue virus and Zika virus, contain a single-stranded positive sense RNA genome that encodes viral proteins essential for replication and also serves as the template for new genome synthesis. As these processes move in opposi
Autor:
Murilo Delgobo, Johan Van Weyenbergh, Tim Dierckx, Joanita Ângela Gonzaga Del Moral, André Báfica, Gaëlle Breton, Darcita Rovaris, Yonne Karoline Tenório de Menezes, Daniel Augusto Gasparin Bueno Mendes, Gabriela F. Rodrigues-Luiz, Edroaldo Lummertz da Rocha, Maíra A. Bicca, Edgar Kozlova, Lucas Mascarin, Daniel O. Patricio, Greicy Dias, Daniel S. Mansur, Márick R Starick
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Monocyte counts are increased during human tuberculosis (TB) but it has not been determined whetherMycobacterium tuberculosis(Mtb) directly regulates myeloid commitment. We demonstrated that exposure toMtbdirects primary human CD34+cells to different
Autor:
Daniel Agb Mendes, Márick R Starick, Daniel O. Patricio, Murilo Delgobo, Edgar Kozlova, Edroaldo Lummertz da Rocha, Maíra A. Bicca, Gaëlle Bretton, André Báfica, Yonne Karoline Tenório de Menezes, Greicy Dias, Lucas Mascarin, Joanita Ângela Gonzaga Del Moral, Daniel S. Mansur, Johan Van Weyenbergh, Gabriela F. Rodrigues-Luiz, Tim Dierckx, Darcita Rovaris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cc0d91c467310aa4d0db927332b6834
https://doi.org/10.7554/elife.47013.045
https://doi.org/10.7554/elife.47013.045
Autor:
Cristina Silvia Borio, Mario Enrique Lozano, Vania Aparecida Mareze, Santiago Mirazo, Renata C. Fleith, Marcos Fabian Bilen, Juan Arbiza, Daniel S. Mansur, Oscar Bruna-Romero
Publikováno v:
Applied Microbiology and Biotechnology. 100:125-133
Two new vaccine candidates against dengue virus (DENV) infection were generated by fusing the coding sequences of the self-budding Z protein from Junin virus (Z-JUNV) to those of two cryptic peptides (Z/DENV-P1 and Z/DENV-P2) conserved on the envelop
Autor:
Norinne Lacerda-Queiroz, Rosa Maria Esteves Arantes, Antônio Lúcio Teixeira, Márcia Carvalho Vilela, Marco Antônio Campos, David Henrique Rodrigues, Daniel S. Mansur, Erna Geessien Kroon, Mauro M. Teixeira
Publikováno v:
Neuroscience Letters. 445:18-22
Herpes simplex virus type 1 (HSV-1) is a human pathogen that may cause severe encephalitis. The development of experimental models of HSV-1 encephalitis is relevant for the comprehension of the immune mechanisms involved in this infection. C57BL/6 mi
Autor:
Daniel S. Mansur, Ralph T. Schwarz, Marco Antônio Campos, Nahid Azzouz, Ralf Weingart, Jörg C. Schmidt, Marianne Garcia Resende, Douglas T. Golenbock, Ulrike Bieker, Ricardo T. Gazzinelli, Françoise Debierre-Grockiego, Richard R. Schmidt
Publikováno v:
The Journal of Immunology. 179:1129-1137
GPIs isolated from Toxoplasma gondii, as well as a chemically synthesized GPI lacking the lipid moiety, activated a reporter gene in Chinese hamster ovary cells expressing TLR4, while the core glycan and lipid moieties cleaved from the GPIs activated
Autor:
Stephen C. Graham, Geoffrey L. Smith, Camilla T.O. Benfield, Jonathan M. Grimes, Laura E. McCoy, M.W. Bahar, Asa P. Oldring, Daniel S. Mansur, Brian J. Ferguson, David I. Stuart
Publikováno v:
The Journal of Biological Chemistry
The IκB kinase (IKK) complex regulates activation of NF-κB, a critical transcription factor in mediating inflammatory and immune responses. Not surprisingly, therefore, many viruses seek to inhibit NF-κB activation. The vaccinia virus B14 protein
Autor:
Carlos Maluquer de Motes, Hongwei Ren, Pavla Strnadova, Daniel S. Mansur, Rebecca P. Sumner, Geoffrey L. Smith, Leonie Unterholzner, Brian J. Ferguson, Andrew G. Bowie
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 9, Iss 2, p e1003183 (2013)
PLoS Pathogens, Vol 9, Iss 2, p e1003183 (2013)
The transcription factor NF-κB is essential for immune responses against pathogens and its activation requires the phosphorylation, ubiquitination and proteasomal degradation of IκBα. Here we describe an inhibitor of NF-κB from vaccinia virus tha