Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Bin Xiao"'
Autor:
Dan-Dan Li, Dong-Hao Bai, Jee H. Jung, Bin Xiao, Ying Wang, Na Zhao, Shang-Wu Jin, Li-Dong Sun, Eun La Kim
Publikováno v:
Biomolecules & Therapeutics
In a search for effective PPAR-γ agonists, 110 clinical drugs were screened via molecular docking, and 9 drugs, including parecoxib, were selected for subsequent biological evaluation. Molecular docking of parecoxib to the ligand-binding domain of P
Autor:
Xijun Wang, Hong-Bin Xiao, Ai-Xia Ju, Yong Hu, Jiao Zhao, Guang Xu, Qing-Song Qie, Qiu-Hong Li
Publikováno v:
World Journal of Traditional Chinese Medicine, Vol 7, Iss 3, Pp 332-338 (2021)
Objective: To explore the mechanism underlying the effect of Panax notoginseng saponins (PNS) on the pharmacokinetics of nifedipine (NF) in rats. Materials and Methods: Twenty-four rats were randomly divided into blank (BL) group, PNS group, NF group
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss, Pp 122-132 (2021)
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss, Pp 122-132 (2021)
Most recombinant adeno-associated virus (AAV) capsids utilized in liver gene therapy have significant levels of pre-existing neutralizing antibodies in the human population. These neutralizing factors limit the patient pools eligible for receiving AA
Publikováno v:
Biological and Pharmaceutical Bulletin. 43:1046-1051
Beta-asarone (β-Asarone), the major component of Acorus tatarinowii Rhizoma, has been proved to be muti-pharmacological activities including anti-inflammation, and which is effective in protecting the central nervous system. However, the effect of
Publikováno v:
Clinical Biochemistry. 74:60-68
Background Colorectal cancer (CRC) is one of the most common cancers worldwide, and emerging lines of evidence have implicated circular RNAs (circRNAs), a novel class of endogenous noncoding RNAs, in CRC development. However, whether plasma circRNAs
Autor:
Jian-Ying Chen, Sheng-Zhi Jiang, Xia Guo, Qiao Li, Jie-Rou Huang, Hui Rao, Li-Hua Zhang, Bin Xiao
Publikováno v:
Autoimmunity. 54(7)
The dysregulated microRNAs (miRNAs) are implicated in the malignancy of lupus nephritis (LN). This work aims to analyse the effect and mechanism of miR-146b-5p in lipopolysaccharides (LPS)-induced model of LN in vitro. The serum samples of LN patient
Autor:
Corina Andronescu, Wolfgang Schuhmann, Bin Xiao, Swapnil Varhade, Simon Schumacher, Olga A. Krysiak, Lars Banko, Alan Savan, Alfred Ludwig, Tobias Löffler, Emmanuel Batsa Tetteh
Publikováno v:
Electrochemical Science Advances
Complex solid solutions (“high entropy alloys” with a single solid-solution phase) hold great promise in electrocatalysis because of their nearly unlim- ited number of different active sites exposed at the surface. It has been shown by theoretica
Autor:
Hidayat Lokman, Huck-Hui Ng, Audrey Tze Ting Khoo, Wei-Yi Ong, Junghyun Jo, Grace Lim, Hoang Dai Tran, Seung-Jae Lee, Weonjin Yu, Lin Yang, Lai Ping Yaw, Ya Yin Chang, Jessica Jiaxin Xie, Kah-Leong Lim, Bin Xiao, Eng-King Tan, Tzuen Yih Saw, Byung Chul Jung, Alfred Xuyang Sun, Hyunsoo Shawn Je
Publikováno v:
Annals of neurology. 90(3)
Objective: We utilized human midbrain-like organoids (hMLOs) generated from human pluripotent stem cells carrying glucocerebrosidase gene (GBA1) and α-synuclein (α-syn; SNCA) perturbations to investigate genotype-to-phenotype relationships in Parki
Publikováno v:
Processes, Vol 9, Iss 1244, p 1244 (2021)
Processes
Volume 9
Issue 7
Processes
Volume 9
Issue 7
In this study, changes in hydrophobic interactions among gluten proteins were analyzed during dough mixing. Size-exclusion high-performance chromatography and two-dimensional fluorescence difference gel electrophoresis were performed on proteins extr
Autor:
Ke-Yu Chen, Xiao-Ming Zhang, Pan Li, Zhu Jiang, Zhi-Yang Xia, Chengyi Shen, Qian Xia, Tao Cheng, Chunrong Zhu, Lei Zhong, Bin Xiao, Changqiang Wu
Publikováno v:
Journal of medicinal chemistry. 64(13)
Liver-specific contrast agents (CAs) can improve the Magnetic resonance imaging (MRI) detection of focal and diffuse liver lesions by increasing the lesion-to-liver contrast. A novel Mn(II) complex, Mn-BnO-TyrEDTA, with a lipophilic group-modified et