Zobrazeno 61 - 70
of 80
pro vyhledávání: '"Bin Xiao"'
Autor:
James W. Voltz, Guangtian Yang, Dao Wen Wang, Bin Xiao, Xuguang Li Li, Xuefeng Yu, Jiangtao Yan, Darryl C. Zeldin, Xiao Xiao
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 334:784-794
Cytochrome P450 (P450)-derived epoxyeicosatrienoic acids (EETs) exert well recognized vasodilatory, diuretic, and tubular fluid-electrolyte transport actions that are predictive of a hypotensive effect. The study sought to determine the improvement o
Autor:
Cheng Luo, Xi-Long Ou, Guo-Xian Ding, Yuan Zhang, Qin-Shi Zhao, Ye Yang, Guo-Sheng Chen, Yi-Ping Xue, Yun Shao, Wei-Hao Sun, Hai-Chen Xu, Bin Xiao, Su-Ming Zhou
Publikováno v:
Cancer Letters. 275:247-255
Although inhibition of cyclooxygenase-2 (COX-2) or activation of peroxisome proliferators-activated receptor gamma (PPAR-gamma) leads to growth inhibition in malignancies, the synergistic anti-tumor effects of combination of COX-2 inhibitor (NS-398)
Publikováno v:
Molecular Biotechnology. 41:138-144
Targeting drugs to tumor cells is a central challenge for improving existing cancer therapies. ACDCRGDCFCG peptide (RGD-4C) binds to alphavbeta3 integrin, which is selectively expressed in tumor blood vessels and on the surface of some tumor cells. I
Autor:
Jia ning Wang, Yong Wang, L. Ashley Cowart, Bin Xiao, Yong Xia, Rui Juan Chen, Dao Wen Wang, Jian Gang Jiang, Xiao Xiao, Shilin Yang
Publikováno v:
Prostaglandins & Other Lipid Mediators. 82:162-174
Endothelial nitric oxide synthase (eNOS) is a key enzyme in NO-mediated cardiovascular homeostasis and its activity is modulated by a variety of hormonal and mechanical stimuli via phosphorylation modification. Our previous study has demonstrated tha
Publikováno v:
Monoclonal antibodies in immunodiagnosis and immunotherapy. 34(3)
Vacuolar proton pyrophosphatase (V-PPase), an electrogenic proton pump widely distributed in non-mammalian species, is one of the important targets for acidocalcisomes. In this study, a novel method of peptide-based antibody generation was performed
Publikováno v:
International immunopharmacology. 25(1)
This study was carried out to determine the effect and mechanism of action of neomangiferin (NG) on high-fat diet-induced nonalcoholic fatty liver disease (NAFLD) in rats. NAFLD rats were randomly assigned into several groups of equal number. NG (50,
Autor:
Jing Zhang, Hai-Xing Mai, Lei Wang, Ke Zheng, Jia-Ning Wang, Zhi-Fang Li, Xiu-Bin Xiao, Wei-Jing Zhang, Hua You, Li Wei, Yuan Liu, Zai-Liang Yang, Wan-Liang Sun, Yan-Qing Wang, Feng Liang
Publikováno v:
Journal of Translational Medicine
Background At present, no effective clinical treatment is available for the late effects of radiation myelopathy. The aim of the present study was to assess the therapeutic effects of human umbilical cord-derived mesenchymal stromal cells (UC-MSCs) i
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 41(12)
Triptolide (TP), a main bioactive component of Tripterygium wilfordii Hook F., is a promising agent for treatment of autoimmune diseases. However, a high incidence of dose-limiting hepatotoxicity was observed in the clinic. Sandwich-cultured rat hepa
Publikováno v:
Cardiology. 124(4)
Objectives: This study aimed to investigate the roles of connective tissue growth factor (CTGF) and transforming growth factor-β1 (TGF-β1) in atrial fibrosis in patients with chronic atrial fibrillation. Methods: Up to 40 cases involving simple mit
Autor:
Christina L. Addison, James Villeneuve, Khalid N. Al-Zahrani, Grant A. Howe, Mohamed Shaad Hasim, Bin Xiao, Luc A. Sabourin, Glenwood D. Goss, Huijun Zhao, Harmanjatinder S. Sekhon, Jim Dimitroulakos
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0150567 (2016)
PLoS ONE, Vol 11, Iss 3, p e0150567 (2016)
Blockade of epidermal growth factor receptor (EGFR) activity has been a primary therapeutic target for non-small cell lung cancers (NSCLC). As patients with wild-type EGFR have demonstrated only modest benefit from EGFR tyrosine kinase inhibitors (TK