Zobrazeno 41 - 50
of 80
pro vyhledávání: '"Bin Xiao"'
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 157(2)
Objective The aim of the study was to examine whether the cannabinoid agonist WIN55212-2 could attenuate ischemic spinal cord injury (SCI) in rats through inhibition of GAPDH/Siah1 signaling. Methods Male Sprague-Dawley rats were distributed randomly
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 96(7)
The cystic fibrosis transmembrane conductance regulator (CFTR) is linked to cell apoptosis and abundantly expressed in brain tissue. Mitochondrial oxidative stress plays a key role in activating apoptotic pathway following cerebral ischemia reperfusi
Publikováno v:
BioMed Research International, Vol 2018 (2018)
BioMed Research International
BioMed Research International
Objectives. Protein arginine methyltransferase 2 (PRMT2) protects against vascular injury-induced intimal hyperplasia; however, little is known about the role of PRMT2 in angiotensin II (Ang II)-induced VSMCs proliferation and inflammation. This rese
Autor:
Fuli Yao, Jing Li, Xiaofang Zhao, Yong Wang, Ying Cheng, Chunyan Duan, Chunhong Feng, Xianming Xia, Rongyang Dai, Guosong Luo, Wenjing Yu, Mei Wei, Hong Zhou, Bin Xiao
Publikováno v:
Molecular medicine reports. 18(2)
Although activating transcription factor 4 (ATF4) is involved in the regulation of numerous biological functions, whether ATF4 has a direct role in liver injury is unknown. The aim of the present study was to investigate the role of ATF4 in liver inj
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
To study the relationship between chromatin condensation, gene transcription and developmental competence during oocyte maturation and to explore the mechanisms by which meiotic arrest maintenance (MAM) and sexual maturity improve oocyte competence,
Defective mitophagy linked to dysfunction in the proteins Parkin and PTEN-induced putative kinase 1 (PINK1) is implicated in the pathogenesis of Parkinson's disease. Although the mechanism by which Parkin mediates mitophagy in a PINK1-dependent manne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2b2b38565d938d834001262cfca734
https://europepmc.org/articles/PMC5633131/
https://europepmc.org/articles/PMC5633131/
Autor:
Yang Jie, Hai Jiang, Lijun Zhao, Chunyu Wang, Dong Xiaolin, Guihua Qiu, Bo Yang, Bin Xiao, Dongling Hu
Publikováno v:
Biomedicine & Pharmacotherapy. 72:125-134
Oridonin, a bioactive diterpenoid isolated from Rabdosia rubescens, has been found to exhibit various anti-tumor effects. In this work, to investigate its pharmacological effects on human colorectal carcinoma HCT-116 and LoVo cells, cell proliferatio
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 78:1504-1513
Liver X receptors (LXRs) has been emerged as negative regulators of cardiomyocytic inflammation. The cellular process of autophagy is believed to play a protective role in myocardium during the inflammatory status. In this study, we investigated the
Publikováno v:
Food and Chemical Toxicology. 71:90-96
Triptolide (TP) is an active component of Tripterygium wilfordii Hook. F and widely used to treat autoimmune and inflammatory diseases. It has been demonstrated that cytochrome P450 (CYP) are involved in the metabolism of TP. However, the underlying
Autor:
Yan Tan, Wei-Bin Xiao, Hai-Ying Yang, Hua Li, Xia Wei, Chuang Lu, Jian-wei Xie, Xiao-Mei Zhuang
Publikováno v:
Toxicological Sciences. 140:40-48
Organophosphorus pesticides are the most widely used pesticides in modern agricultural systems to ensure good harvests. Isocarbophos (ICP), with a potent acetylcholinesterase inhibitory effect is widely utilized to control a variety of leaf-eating an