Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Bart Staels"'
Autor:
Sarah Costantino, Przemyslaw Blyszczuk, Johan Auwerx, Melanie Greter, Anne Tailleux, Urs Eriksson, Julien Weber, Christian M. Matter, Simona Stivala, Sokrates Stein, Jürg H. Beer, Melroy X. Miranda, Bart Staels, Thomas F. Lüscher, Kathrin Nussbaum, Tasneem Arsiwala, Burkhard Becher, Francesco Paneni, Raul Mostoslavsky, Michael O. Hottiger, Lavinia Bisceglie, Lambertus J. van Tits, Daniel S. Gaul, Jürgen Pahla
Publikováno v:
Journal of Molecular and Cellular Cardiology. 139:24-32
Aims Sirtuin 6 (Sirt6) is a NAD+-dependent deacetylase that plays a key role in DNA repair, inflammation and lipid regulation. Sirt6-null mice show severe metabolic defects and accelerated aging. Macrophage-foam cell formation via scavenger receptors
Autor:
Mónica Vázquez-Del Mercado, Hugo Christian Monroy-Ramirez, Jorge Gutiérrez-Cuevas, Jesús García-Bañuelos, José Alfredo Domínguez-Rosales, Jose Navarro-Partida, Jose Vera-Cruz, Arturo Santos-Garcia, Ana Sandoval-Rodriguez, Juan Armendáriz-Borunda, Jorge Silva-Gomez, Alejandra Meza-Rios, Marina Galicia-Moreno, Bart Staels
Publikováno v:
Hepatology Communications, Vol 4, Iss 3, Pp 434-449 (2020)
Hepatology Communications
Hepatology Communications
Nonalcoholic steatohepatitis (NASH) is recognized by hepatic lipid accumulation, inflammation, and fibrosis. No studies have evaluated the prolonged‐release pirfenidone (PR‐PFD) properties on NASH features. The aim of this study is to evaluate ho
Autor:
Philippe Gailly, Anna Kreis, Karelle Leroy, Bart Staels, Nathalie Pierrot, Jean Pierre Brion, Francisco Saez-Orellana, Eric Bauge, Charles Duyckaerts, Jean-Noël Octave, Floriane Ribeiro, Thomas Leroy, Fanny Lalloyer
Publikováno v:
JCI Insight
JCI Insight, American Society for Clinical Investigation, 2021, ⟨10.1172/jci.insight.150099⟩
JCI insight, 6 (16
JCI Insight, 2021, ⟨10.1172/jci.insight.150099⟩
JCI Insight, American Society for Clinical Investigation, 2021, ⟨10.1172/jci.insight.150099⟩
JCI insight, 6 (16
JCI Insight, 2021, ⟨10.1172/jci.insight.150099⟩
Among genetic susceptibility loci associated with late-onset Alzheimer disease (LOAD), genetic polymorphisms identified in genes encoding lipid carriers led to the hypothesis that a disruption of lipid metabolism could promote disease progression. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee14c391640ff77c086cb59c2c3a440
https://hal.sorbonne-universite.fr/hal-03280763/file/150099.1-20210701105952-covered-e0fd13ba177f913fd3156f593ead4cfd.pdf
https://hal.sorbonne-universite.fr/hal-03280763/file/150099.1-20210701105952-covered-e0fd13ba177f913fd3156f593ead4cfd.pdf
Autor:
Denis A. Mogilenko, Delphine Staumont-Sallé, Geert van Loo, Wim Declercq, Peter Vandenabeele, Michael Devos, David Dombrowicz, Peter Tougaard, C. Becquart, Claus Bachert, Sandrine Quemener, Bart Staels, Barbara Gilbert, Hélène Dehondt, Sébastien Fleury
Publikováno v:
Journal of Investigative Dermatology. 139:135-145
Keratinocytes are key players in chronic inflammatory skin diseases. A20 regulates NF-κB-dependent expression of proinflammatory genes and cell death, but the impact of its expression in keratinocytes on systemic inflammation and skin disorders has
Autor:
Timon E. Adolph, Eduard M. Rubin, Sabrina Folie, Claudia Ress, Bart Staels, Bernhard Radlinger, Maximilian Hofer, Michael Roden, Jochen Dobner, Susanne Kaser, Herbert Tilg, Kerstin Rufinatscha
Publikováno v:
Nutrition, metabolism, and cardiovascular diseases : NMCD. 31(3)
Background and aims Western dietary habits are partially characterized by increased uptake of fructose, which contributes to metabolic dysregulation and associated liver diseases. For example, a diet enriched with fructose drives insulin resistance a
Autor:
Marta Ballanti, Omero Alessandro Paoluzi, Massimo Federici, Anna Artati, Nikolaus Marx, Jerzy Adamski, Claudia Goettsch, Geltrude Mingrone, Maria Mavilio, Robert Stoehr, Bart Staels, Rémy Burcelin, Rossella Menghini, Michael Heiser, Giovanni Monteleone, Lorenzo De Angelis, Ben Arpad Kappel
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 36, Iss, Pp-(2020)
Mol. Metab. 36:100976 (2020)
Molecular Metabolism, Vol 36, Iss, Pp-(2020)
Mol. Metab. 36:100976 (2020)
Objective The metabolic influence of gut microbiota plays a pivotal role in the pathogenesis of cardiometabolic diseases. Antibiotics affect intestinal bacterial diversity, and long-term usage has been identified as an independent risk factor for ath
Autor:
François Pattou, Violeta Raverdy, Steve Lancel, Gregory Baud, Alexis Boulinguiez, Christian Duhem, Hélène Duez, Hélène Verkindt, Robert Caiazzo, Bart Staels, Camille Marciniak
Publikováno v:
Acta Diabetologica
Acta Diabetologica, 2020, 57 (7), pp.819-826. ⟨10.1007/s00592-020-01490-z⟩
Acta Diabetologica, Springer Verlag, 2020, 57 (7), pp.819-826. ⟨10.1007/s00592-020-01490-z⟩
Acta Diabetologica, Springer Verlag, 2020, ⟨10.1007/s00592-020-01490-z⟩
Acta Diabetologica, 2020, 57 (7), pp.819-826. ⟨10.1007/s00592-020-01490-z⟩
Acta Diabetologica, Springer Verlag, 2020, 57 (7), pp.819-826. ⟨10.1007/s00592-020-01490-z⟩
Acta Diabetologica, Springer Verlag, 2020, ⟨10.1007/s00592-020-01490-z⟩
International audience; AIMS:Not all people with obesity become glucose intolerant, suggesting differential activation of cellular pathways. The unfolded protein response (UPR) may contribute to the development of insulin resistance in several organs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b47d963840df2752a56cf4bf3e6fb8
https://www.hal.inserm.fr/inserm-02488979
https://www.hal.inserm.fr/inserm-02488979
Autor:
Nicolas Debry, Claudia Mourran, Augustin Coisne, David M. Smadja, Bart Staels, Antoine Capel, Christoph Nix, Christian Latremouille, Alexandre Ung, Cécile V. Denis, Natacha Rousse, Hugues Spillemaeker, Eric Van Belle, Cristian Preda, Alain Carpentier, Antoine Rauch, Svenja Barth, Pascal Leprince, Gilles Lemesle, Claudine Caron, André Vincentelli, Marjorie Richardson, Camille Paris, Piet Jansen, Emmanuel Robin, Annabelle Dupont, Julien Amour, Yoann Sottejeau, Peter J. Lenting, Guillaume Schurtz, Flavien Vincent, Valentin Loobuyck, Mickael Rosa, Sophie Susen, Delphine Corseaux, Cedric Delhaye, Thomas Hubert, Mouhamed Moussa, Emmanuelle Jeanpierre, Valérie Gomane
Publikováno v:
Journal of the American College of Cardiology
Journal of the American College of Cardiology, 2018, 71 (19), pp.2106-2118. ⟨10.1016/j.jacc.2018.02.075⟩
Journal of the American College of Cardiology, 2018, 71 (19), pp.2106-2118. ⟨10.1016/j.jacc.2018.02.075⟩
International audience; Background: The main risk factor for bleeding in patients with continuous-flow mechanical circulatory support (CF-MCS) is the acquired von Willebrand factor (VWF) defect related to the high shear-stress forces developed by the
Autor:
André Vincentelli, Yoann Sottejeau, Francis Juthier, Annabelle Dupont, Madjid Tagzirt, Mickael Rosa, Bart Staels, Delphine Corseaux, Eric Van Belle, Sophie Susen, Camille Paris, R. Jashari, Antoine Rauch, Emmanuel Robin
Publikováno v:
Acta Diabetologica. 54:551-560
Calcific aortic valve disease (CAVD) affects 2–6% of the population over 65 years, and age, gender, smoking, overweight, dyslipidemia, diabetes contribute to the development of this disease. CAVD results, in part, from the osteoblast differentiatio
Autor:
Kadiombo Bantubungi, Luc Buée, Anne Tailleux, David Blum, Emmanuelle Vallez, Sylvie Raison, Elodie Marciniak, Didier Vieau, Tariq Ahmed, Raphaëlle Caillierez, Steve Lancel, Detlef Balschun, Antoine Leboucher, Aurelie Joly-Amado, Emilie Caron, Sabiha Eddarkaoui, Kevin Carvalho, Bart Staels, Malika Hamdane
Publikováno v:
Neurobiology of Disease
Neurobiology of Disease, 2019, 125, pp.14-22. ⟨10.1016/j.nbd.2019.01.008⟩
Neurobiology of Disease, Elsevier, 2019, 125, pp.14-22. ⟨10.1016/j.nbd.2019.01.008⟩
Neurobiology of Disease, Vol 125, Iss, Pp 14-22 (2019)
Neurobiology of Disease, Elsevier, 2019, 125, pp.14-22. 〈10.1016/j.nbd.2019.01.008〉
Neurobiology of Disease, 2019, 125, pp.14-22. ⟨10.1016/j.nbd.2019.01.008⟩
Neurobiology of Disease, Elsevier, 2019, 125, pp.14-22. ⟨10.1016/j.nbd.2019.01.008⟩
Neurobiology of Disease, Vol 125, Iss, Pp 14-22 (2019)
Neurobiology of Disease, Elsevier, 2019, 125, pp.14-22. 〈10.1016/j.nbd.2019.01.008〉
International audience; Accumulation of hyper-phosphorylated and aggregated Tau proteins is a neuropathological hallmark of Alzheimer's Disease (AD) and Tauopathies. AD patient brains also exhibit insulin resistance. Whereas, under normal physiologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06908d9b26ee8bf45b6b42dced23ef06
https://www.hal.inserm.fr/inserm-02350072
https://www.hal.inserm.fr/inserm-02350072