Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ayako Suzuki"'
Autor:
Ikei S. Kobayashi, Daisuke Shibahara, Yuji Shibata, Akihiro Ohashi, Yukie Kashima, Katsuya Tsuchihara, Yutaka Suzuki, Kosuke Tanaka, Koichi Goto, Hiroki Izumi, Masanori Fujii, Ayako Suzuki, Hibiki Udagawa, Susumu Kobayashi, David Plotnick, Kyoko Muto, Masahide Seki
Publikováno v:
Cancer Res
Tumor heterogeneity underlies resistance to tyrosine kinase inhibitors (TKI) in lung cancers harboring EGFR mutations. Previous evidence suggested that subsets of preexisting resistant cells are selected by EGFR-TKI treatment, or alternatively, that
Autor:
Sanda Win, Neil Kaplowitz, Brad Wanken, Ying Wang, Robert W.M. Min, Meng Li, Gary Kanel, Filbert W.M. Aung, Ayako Suzuki, Yibu Chen, Tin Aung Than, Susan F. Murray, Mariam Aghajan, Jun Zhang
Publikováno v:
Hepatology
BACKGROUND AND AIMS The hepatic mitogen-activated protein kinase (MAPK) cascade leading to c-Jun N-terminal kinase (JNK) activation has been implicated in the pathogenesis of nonalcoholic fatty liver (NAFL)/NASH. In acute hepatotoxicity, we previousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83508583500ef97455ec6feb4fe5aab6
https://europepmc.org/articles/PMC8639630/
https://europepmc.org/articles/PMC8639630/
Autor:
Yoshitaka Sakamoto, Yutaka Suzuki, Takashi Kohno, Liu Xu, Susumu Kobayashi, Yukie Kashima, Yoko Shimada, Ayako Suzuki, Akihiro Ohashi, Yuichi Shiraishi, Masahide Seki, Masahiro Kasahara, Katsuya Tsuchihara, Toshiyuki T. Yokoyama, Noriko Motoi
Publikováno v:
Genome Res
Here, we report the application of a long-read sequencer, PromethION, for analyzing human cancer genomes. We first conducted whole-genome sequencing on lung cancer cell lines. We found that it is possible to genotype known cancerous mutations, such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350dea2e4af6433401850b314f260aa4
https://europepmc.org/articles/PMC7545141/
https://europepmc.org/articles/PMC7545141/
Autor:
Elana B Mitchel, Cynthia Behling, Ayako Suzuki, Katherine P. Yates, Tiange Liu, Noel T. Mueller, Joel E. Lavine
Publikováno v:
J Clin Endocrinol Metab
Context Sex hormones have been linked with presence and severity of nonalcoholic fatty liver disease (NAFLD) in adults, but it is unknown if they affect severity of pediatric NAFLD. Objective To examine associations of circulating SHBG, estrogens, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14cfa3fddea199bf5073923dfcc6cfc
https://europepmc.org/articles/PMC7494240/
https://europepmc.org/articles/PMC7494240/
Autor:
Anna Mae Diehl, Gregory A. Michelotti, Cynthia D. Guy, Thiago A. Pereira, Mariana Verdelho Machado, Ann Marie Zavacki, Dawn Piercy, Leandi Krüger, Manal F. Abdelmalek, Brittany N. Bohinc, Herbert Pang, Guanhua Xie, Marzena Swiderska-Syn, Ayako Suzuki
Publikováno v:
Endocrinology
Thyroid hormone (TH) is important for tissue repair because it regulates cellular differentiation. Intrahepatic TH activity is controlled by both serum TH levels and hepatic deiodinases. TH substrate (T4) is converted into active hormone (T3) by deio
Publikováno v:
Current opinion in neurobiology. 44
Slow wave activity (SWA) during slow wave sleep (SWS) is the best indicator of the sleep homeostasis. The intensity of the SWA observed during SWS that follows prolonged waking is directly correlated with the duration of prior waking and its intensit
Autor:
Wei Chen, Cynthia D. Guy, Ayako Suzuki, Jiuyi Lu, Anna Mae Diehl, Fatima A. Rangwala, Manal F. Abdelmalek, James L. Burchette
Publikováno v:
The Journal of Pathology. 224:401-410
Ballooned hepatocytes distinguish non-alcoholic steatohepatitis (NASH) from steatosis. Such cells contain dilated endoplasmic reticulum and ubiquitin aggregates, characteristics of endoplasmic reticulum stress. Hepatocyte ballooning increases the ris
Publikováno v:
Metabolism. 59:177-185
In obese subjects, the liver may be differentially affected by significant weight loss depending on as yet unknown factors. We explored clinical factors associated with serum alanine aminotransferase (ALT) changes during significant weight loss in a
Autor:
Takao Hashimoto, Kayoko Higuchi, Ayako Suzuki-Tsuchiya, Shu-ichi Ikeda, Kana Tojo, Taiji Akamatu
Publikováno v:
Amyloid. 16:174-177
Two male patients aged 72 and 77 were found to have transthyretin (TTR) immunoreactive amyloid deposits in their gastrointestinal tracts when they underwent surgery for gastric and sigmoid colon cancer, respectively. They had no cardiac symptoms and
Autor:
Keith D. Lindor, Ayako Suzuki, Paul Angulo, Judith A Van de Water, Roberta A. Jorgensen, M. Eric Gershwin
Publikováno v:
Autoimmunity, vol 9, iss 2
Developmental Immunology
Developmental immunology, vol 9, iss 2
Clinical and Developmental Immunology, Vol 9, Iss 2, Pp 55-61 (2002)
Developmental Immunology
Developmental immunology, vol 9, iss 2
Clinical and Developmental Immunology, Vol 9, Iss 2, Pp 55-61 (2002)
Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease characterized by the immunological destruction of intralobular bile ducts and serum anti-mitochondrial antibodies (AMA). Based upon previous work of oral tolerance and autoimmunit