Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Ajay P. Singh"'
Autor:
Nikhil Tyagi, Ajay P. Singh, Seema Singh, James E. Carter, Ahmed Al-Ghadhban, Arun Bhardwaj, Sachin Kumar Deshmukh, Haseeb Zubair, Sanjeev K. Srivastava, Donna Lynn Dyess
Publikováno v:
Cancer Letters. 396:21-29
Breast cancer (BC) continues to be the most frequently diagnosed cancer in American women, which disproportionately affects women of African-American (AA) descent. Previously, we reported greater serum levels of resistin in AA BC patients relative to
Autor:
Mohammad Aslam Khan, Shafquat Azim, Aamir Ahmad, Girijesh Kumar Patel, Haseeb Zubair, Seema Singh, Sachin Pai, Ajay P. Singh
Pathogenesis of pancreatic cancer (PC) involves both genetic and epigenetic alterations. While genetic aberrations have been the focus of a majority of studies, recent research has highlighted the benefit of therapeutically targeting epigenetic chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e962d0ed9fc0f558be5c26285a2ceb2
https://doi.org/10.1016/b978-0-12-812494-9.00012-3
https://doi.org/10.1016/b978-0-12-812494-9.00012-3
Publikováno v:
Cancer Research. 80:5070-5070
Breast cancer (BC) is the most frequently diagnosed malignancy and continues to be the second leading cause of cancer-related death in women in the United States. Dysregulation of Let-7 family microRNAs is observed in BC and associated with disease p
Autor:
Daniel Cameron, Moh’d Khushman, Josiah B Perry, William R. Taylor, Ajay P. Singh, Girijesh Kumar Patel, Cindy Nelson, Osama Abdul-Rahim, Rodney P. Rocconi, Arthur E. Frankel, Laith Abushahin
Publikováno v:
Journal of Cancer Research and Therapeutics. 16:950
Despite recent advances in treatment with multidrug chemotherapy regimens, outcomes of patients with advanced pancreatic ductal adenocarcinoma (PDAC) remain very poor. Treatment with targeted therapies has shown marginal benefits due to intrinsic or
Autor:
Sanjeev K. Srivastava, Bin Wang, Ahmed Al-Ghadhban, Seema Singh, James E. Carter, Nikhil Tyagi, Shafquat Azim, Sachin Kumar Deshmukh, Ajay P. Singh, Aamir Ahmad
The ETS family transcription factor ETV4 is aberrantly expressed in a variety of human tumors and plays an important role in carcinogenesis through upregulation of relevant target gene expression. Here, it is demonstrated that ETV4 is overexpressed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf8bb8b93f2c0e1d0a5bff3f7b23a09
https://europepmc.org/articles/PMC5805611/
https://europepmc.org/articles/PMC5805611/
Autor:
Seema Singh, Arun Bhardwaj, Bin Wang, Sanjeev K. Srivastava, Sumit Arora, Nikhil Tyagi, Steve McClellan, Joel Andrews, Ajay P. Singh
Publikováno v:
British Journal of Cancer
Background: Previously, miR-345 was identified as one of the most significantly downregulated microRNAs in pancreatic cancer (PC); however, its functional significance remained unexplored. Methods: miR-345 was overexpressed in PC cells by stable tran
Autor:
Sanjeev K. Srivastava, Nikhil Tyagi, Arun Bhardwaj, Ajay P. Singh, Saravanakumar Marimuthu, Seema Singh, James E. Carter, Valeria Dal Zotto, Donna Lynn Dyess, Sachin Kumar Deshmukh
Publikováno v:
Oncotarget
African-American (AA) women with breast cancer (BC) are diagnosed with more aggressive disease, have higher risk of recurrence and poorer prognosis as compared to Caucasian American (CA) women. Therefore, it is imperative to define the factors associ
Autor:
Ajay P. Singh, Seema Singh, Nikhil Tyagi, Steven McClellan, Sumit Arora, Sanjeev K. Srivastava, Arun Bhardwaj, Joel Andrews, James E. Carter
Publikováno v:
Oncotarget
Emerging data highlight the significance of chemokine (C-X-C motif) ligand 12/chemokine (C-X-C motif) receptor 4 (CXCL12/CXCR4) signaling axis in the chemoresistance of several malignancies, including prostate cancer (PCa); however, underlying mechan
Autor:
Girijesh Kumar Patel, Anu Singh Maharjan, Spencer Liles, Gwendolyn A. McMillin, Leander Grimm, Bin Wang, Peter J. Hosein, Paul Rider, William R. Taylor, Arthur E. Frankel, John Hunter, Moh’d Khushman, Clayton Smith, Cindy Nelson, Saad Awan, Sachin Pai, Ajay P. Singh
Publikováno v:
Journal of Clinical Oncology. 37:545-545
545 Background: Fluoropyrimidines are antimetabolites that target the S phase of the cell cycle. The active metabolite, 5-fluorodeoxyuridine monophosphate inhibits thymidylate synthase (TS) enzyme, thus preventing DNA synthesis and ultimately cell de
Publikováno v:
Current Molecular Medicine. 12:1244-1252
Honokiol ((3’,5-di-(2-propenyl)-1,1’-biphenyl-2,2’-diol) is a bioactive natural product derived from Magnolia spp. Recent studies have demonstrated anti-inflammatory, anti-angiogenic, anti-oxidative and anti-cancer properties of honokiol in vit