Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Olle Söder"'
Leydig cell steroidogenesis unexpectedly escapes mitochondrial dysfunction in prematurely aging mice
Autor:
Olle Söder, Luise Landreh, Jan Nedergaard, Nina Atanassova, Natasa Petrovic, Mi Hou, Daniel Edgar, Irina G. Shabalina, Kjell Hultenby, Natalia Gibanova, Konstantin Svechnikov
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 29(8)
Point mutations and deletions of mitochondrial DNA (mtDNA) accumulate in tissues during aging in animals and humans and are the basis for mitochondrial diseases. Testosterone synthesis occurs in the mitochondria of Leydig cells. Mitochondrial dysfunc
Publikováno v:
Human Reproduction. 21:2801-2809
BACKGROUND: The high mobility group box chromosomal protein 1 (HMGB1) was originally shown to be a nuclear DNA-binding protein that activates transcription and promotes differentiation. More recently, there have been reports that HMGB1 may also funct
Publikováno v:
The EMBO journal. 25(17)
An essential aspect of male reproductive capacity is the immediate availability of fertilization-ready spermatozoa. To ensure this, most mammals rely on post-testicular sperm maturation. In epididymis, germ cells are matured and stored in a quiescent
Autor:
Julius Hreinsson, Ralf F. Pettersson, Kerstin Sollerbrant, Outi Hovatta, Olle Söder, Mona-Lisa Strand, Lennart Philipson, Momina Mirza
Publikováno v:
Experimental cell research. 312(6)
The coxsackievirus and adenovirus receptor (CAR) is a transmembrane protein important for viral binding to target cells. Using RT-PCR, Western analysis, GST pull-down assay and indirect immunofluorescence, it was shown that CAR is expressed in male g