Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Bin Xiao"'
Publikováno v:
Biological and Pharmaceutical Bulletin. 43:1046-1051
Beta-asarone (β-Asarone), the major component of Acorus tatarinowii Rhizoma, has been proved to be muti-pharmacological activities including anti-inflammation, and which is effective in protecting the central nervous system. However, the effect of
Autor:
Ke-Yu Chen, Xiao-Ming Zhang, Pan Li, Zhu Jiang, Zhi-Yang Xia, Chengyi Shen, Qian Xia, Tao Cheng, Chunrong Zhu, Lei Zhong, Bin Xiao, Changqiang Wu
Publikováno v:
Journal of medicinal chemistry. 64(13)
Liver-specific contrast agents (CAs) can improve the Magnetic resonance imaging (MRI) detection of focal and diffuse liver lesions by increasing the lesion-to-liver contrast. A novel Mn(II) complex, Mn-BnO-TyrEDTA, with a lipophilic group-modified et
Publikováno v:
Neuroreport. 31(18)
The role of norepinephrine of the hippocampal dentate gyrus in spatial learning and memory alteration induced by chronic restraint stress (CRS, 3 h/day, 6 weeks) was investigated in aged rats. Spatial learning and memory were assessed by the Morris w
Publikováno v:
International Journal of Molecular Medicine
In the present study, we investigated the role of activating transcription factor 6 (ATF6) in the mechanism by which chronic intermittent hypoxia (CIH) increases tolerance to myocardial ischemia/reperfusion (I/R). Experiments were conducted using a r
Autor:
Ze‑Zhou Feng, Zhao Jian, Peng Liu, Ying‑Bin Xiao, Wei‑Kun Jia, Yun Zhu, Liang Zhao, Jingwei Li, Si‑Yi He
Publikováno v:
Molecular Medicine Reports. 12:6903-6910
MicroRNAs (miRs) regulate a number of physiological and pathological processes, including myocardial chronic hypoxia. Previous studies revealed that the expression of miR-146b is increased in vitro and in vivo following the induction of hypoxia. In t
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 157(2)
Objective The aim of the study was to examine whether the cannabinoid agonist WIN55212-2 could attenuate ischemic spinal cord injury (SCI) in rats through inhibition of GAPDH/Siah1 signaling. Methods Male Sprague-Dawley rats were distributed randomly
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 96(7)
The cystic fibrosis transmembrane conductance regulator (CFTR) is linked to cell apoptosis and abundantly expressed in brain tissue. Mitochondrial oxidative stress plays a key role in activating apoptotic pathway following cerebral ischemia reperfusi
Publikováno v:
Food and Chemical Toxicology. 71:90-96
Triptolide (TP) is an active component of Tripterygium wilfordii Hook. F and widely used to treat autoimmune and inflammatory diseases. It has been demonstrated that cytochrome P450 (CYP) are involved in the metabolism of TP. However, the underlying
Autor:
James W. Voltz, Guangtian Yang, Dao Wen Wang, Bin Xiao, Xuguang Li Li, Xuefeng Yu, Jiangtao Yan, Darryl C. Zeldin, Xiao Xiao
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 334:784-794
Cytochrome P450 (P450)-derived epoxyeicosatrienoic acids (EETs) exert well recognized vasodilatory, diuretic, and tubular fluid-electrolyte transport actions that are predictive of a hypotensive effect. The study sought to determine the improvement o
Autor:
Jia ning Wang, Yong Wang, L. Ashley Cowart, Bin Xiao, Yong Xia, Rui Juan Chen, Dao Wen Wang, Jian Gang Jiang, Xiao Xiao, Shilin Yang
Publikováno v:
Prostaglandins & Other Lipid Mediators. 82:162-174
Endothelial nitric oxide synthase (eNOS) is a key enzyme in NO-mediated cardiovascular homeostasis and its activity is modulated by a variety of hormonal and mechanical stimuli via phosphorylation modification. Our previous study has demonstrated tha