Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Bin Xiao"'
Autor:
Dan-Dan Li, Dong-Hao Bai, Jee H. Jung, Bin Xiao, Ying Wang, Na Zhao, Shang-Wu Jin, Li-Dong Sun, Eun La Kim
Publikováno v:
Biomolecules & Therapeutics
In a search for effective PPAR-γ agonists, 110 clinical drugs were screened via molecular docking, and 9 drugs, including parecoxib, were selected for subsequent biological evaluation. Molecular docking of parecoxib to the ligand-binding domain of P
Autor:
Xijun Wang, Hong-Bin Xiao, Ai-Xia Ju, Yong Hu, Jiao Zhao, Guang Xu, Qing-Song Qie, Qiu-Hong Li
Publikováno v:
World Journal of Traditional Chinese Medicine, Vol 7, Iss 3, Pp 332-338 (2021)
Objective: To explore the mechanism underlying the effect of Panax notoginseng saponins (PNS) on the pharmacokinetics of nifedipine (NF) in rats. Materials and Methods: Twenty-four rats were randomly divided into blank (BL) group, PNS group, NF group
Publikováno v:
Biological and Pharmaceutical Bulletin. 43:1046-1051
Beta-asarone (β-Asarone), the major component of Acorus tatarinowii Rhizoma, has been proved to be muti-pharmacological activities including anti-inflammation, and which is effective in protecting the central nervous system. However, the effect of
Autor:
Xijing Zhang, Dandan Cheng, Jiajia Wang, Haixing Zhong, Zhenhua Jiang, Zongping Fang, Ting Gu, Wugang Hou, Bin-Xiao Su, Yi Li, Haiyun Guo, Shiquan Wang
Publikováno v:
Brain research. 1757
Rosmarinic acid (RA), a natural polyphenol, possesses potent antioxidant and anti-inflammatory activities. To evaluate the ability of RA to cure ischemic stroke and post-stroke depression (PSD), rats were treated with various doses of RA after cerebr
Autor:
Wen Jiang, Jingjing Tan, Xiao Hao, Weimin Wang, Yongjun Zhang, Zhiyu Fang, Ge Wang, Aoxue Lu, Bin Xiao, Jia Li
Publikováno v:
Journal of food biochemistryREFERENCES. 45(3)
Our previous study has optimized the acid hydrolysis process of pumpkin polysaccharides (PPe) with scavenging ability based on central composite design. The aim of this study was to explore the in vivo-antioxidant ability of PPe and pumpkin polysacch
Publikováno v:
European journal of medicinal chemistry. 202
Celiac disease affects approximately 1% of the population and is a major public health problem worldwide. It is trigged by gluten-derived peptides, which have unusually high proline-glutamine motif content and are highly resistant to proteolysis by d
Autor:
Xiao-ling Zhu, Xin Chen, Yu-Yuan Min, Yu Wang, Xu Li, Bin-Xiao Su, Wei Wang, Jia Huo, Jian-Ming Pei
Publikováno v:
Brain Research. 1659:113-120
Paraplegia caused by spinal cord ischemia is a severe complication following surgeries in the thoracic aneurysm. HMGB1 has been recognized as a key mediator in spinal inflammatory response after spinal cord injury. Electroacupuncture (EA) pretreatmen
Publikováno v:
Journal of global antimicrobial resistance. 18
Objectives Human health is seriously threatened by metallo-β-lactamase (MBL)-mediated bacterial antimicrobial resistance, among which New Delhi metallo-β-lactamase 1 (NDM-1) has received great attention due to its extensive substrate profile and hi
Autor:
Bin Xiao, Genghong Tu, Malcolm Xing, Yue Wu, Li Ying, Lin Zhang, Mohammad Ali Darabi, Yutong Liu, Lu Zhang, Jinhua Xue, Lu Huang
Publikováno v:
Materials scienceengineering. C, Materials for biological applications. 100
Parkinson's disease (PD) is a long-term neurodegenerative disorders that characterized by a progressive loss of dopaminergic neurons in substantia nigra pars compacta (SNc). Bone marrow stromal cells (BMSCs) are promising therapeutic agents for neuro
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 157(2)
Objective The aim of the study was to examine whether the cannabinoid agonist WIN55212-2 could attenuate ischemic spinal cord injury (SCI) in rats through inhibition of GAPDH/Siah1 signaling. Methods Male Sprague-Dawley rats were distributed randomly