Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Bin Xiao"'
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss, Pp 122-132 (2021)
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss, Pp 122-132 (2021)
Most recombinant adeno-associated virus (AAV) capsids utilized in liver gene therapy have significant levels of pre-existing neutralizing antibodies in the human population. These neutralizing factors limit the patient pools eligible for receiving AA
Autor:
Jian-Ying Chen, Sheng-Zhi Jiang, Xia Guo, Qiao Li, Jie-Rou Huang, Hui Rao, Li-Hua Zhang, Bin Xiao
Publikováno v:
Autoimmunity. 54(7)
The dysregulated microRNAs (miRNAs) are implicated in the malignancy of lupus nephritis (LN). This work aims to analyse the effect and mechanism of miR-146b-5p in lipopolysaccharides (LPS)-induced model of LN in vitro. The serum samples of LN patient
Autor:
Yongjun Zhang, Jingjing Tan, Qiqi Huang, Jiangying Zeng, Ge Wang, Shuang Chen, Bin Xiao, jing yao, Tao Feng
Publikováno v:
International journal of biological macromolecules. 187
An efficient extraction method of Auricularia auricula polysaccharides (AAPs) by neutral protease was developed and optimized by response surface methodology. AAPs were graded by stepwise ethanol precipitation, the fraction with high recovery rate an
Autor:
Xijing Zhang, Dandan Cheng, Jiajia Wang, Haixing Zhong, Zhenhua Jiang, Zongping Fang, Ting Gu, Wugang Hou, Bin-Xiao Su, Yi Li, Haiyun Guo, Shiquan Wang
Publikováno v:
Brain research. 1757
Rosmarinic acid (RA), a natural polyphenol, possesses potent antioxidant and anti-inflammatory activities. To evaluate the ability of RA to cure ischemic stroke and post-stroke depression (PSD), rats were treated with various doses of RA after cerebr
Autor:
Xiao-ling Zhu, Xin Chen, Yu-Yuan Min, Yu Wang, Xu Li, Bin-Xiao Su, Wei Wang, Jia Huo, Jian-Ming Pei
Publikováno v:
Brain Research. 1659:113-120
Paraplegia caused by spinal cord ischemia is a severe complication following surgeries in the thoracic aneurysm. HMGB1 has been recognized as a key mediator in spinal inflammatory response after spinal cord injury. Electroacupuncture (EA) pretreatmen
Publikováno v:
Skeletal Muscle
Skeletal Muscle, Vol 9, Iss 1, Pp 1-16 (2019)
Skeletal Muscle, Vol 9, Iss 1, Pp 1-16 (2019)
Background Growth differentiation factor 11 (GDF11) is a member of the transforming growth factor β superfamily. The GDF11 propeptide, which is derived from the GDF11 precursor protein, blocks the activity of GDF11 and its homolog, myostatin, which
Autor:
Yongyin He, Jingrun Lu, Jing Qu, Weiwei Li, Jianfeng Hang, Wenbo Hao, Zhenzhan Kuang, Zhaohui Sun, Ting Lei, Chun Deng, Weiyun Zhang, Bin Xiao, Linhai Li, Lidan Chen, Quan Zhou
Publikováno v:
Molecular Carcinogenesis
Glutamate Ionotropic Receptor Kainate Type Subunit 3 (GRIK3) is an important excitatory neurotransmitter receptor that plays a significant role in various neurodegenerative diseases. However, the biological functions of GRIK3 in malignancies are larg
Autor:
Yanli Zhan, Wenbo Hao, Daxiang Chen, Zhenzhan Kuang, Bin Xiao, Yang Gao, Shuhong Luo, Ming Li
Publikováno v:
The Korean Journal of Parasitology. 54:21-29
The sodium hydrogen exchanger 1 (NHE1), which functions in maintaining the ratio of Na(+) and H(+) ions, is widely distributed in cell plasma membranes. It plays a prominent role in pH balancing, cell proliferation, differentiation, adhesion, and mig
Autor:
Ze‑Zhou Feng, Zhao Jian, Peng Liu, Ying‑Bin Xiao, Wei‑Kun Jia, Yun Zhu, Liang Zhao, Jingwei Li, Si‑Yi He
Publikováno v:
Molecular Medicine Reports. 12:6903-6910
MicroRNAs (miRs) regulate a number of physiological and pathological processes, including myocardial chronic hypoxia. Previous studies revealed that the expression of miR-146b is increased in vitro and in vivo following the induction of hypoxia. In t
Publikováno v:
BioMed Research International, Vol 2018 (2018)
BioMed Research International
BioMed Research International
Objectives. Protein arginine methyltransferase 2 (PRMT2) protects against vascular injury-induced intimal hyperplasia; however, little is known about the role of PRMT2 in angiotensin II (Ang II)-induced VSMCs proliferation and inflammation. This rese