Zobrazeno 11 - 20
of 28
pro vyhledávání: '"Bin Xiao"'
Autor:
Yongyin He, Jingrun Lu, Jing Qu, Weiwei Li, Jianfeng Hang, Wenbo Hao, Zhenzhan Kuang, Zhaohui Sun, Ting Lei, Chun Deng, Weiyun Zhang, Bin Xiao, Linhai Li, Lidan Chen, Quan Zhou
Publikováno v:
Molecular Carcinogenesis
Glutamate Ionotropic Receptor Kainate Type Subunit 3 (GRIK3) is an important excitatory neurotransmitter receptor that plays a significant role in various neurodegenerative diseases. However, the biological functions of GRIK3 in malignancies are larg
Publikováno v:
International Journal of Molecular Medicine
In the present study, we investigated the role of activating transcription factor 6 (ATF6) in the mechanism by which chronic intermittent hypoxia (CIH) increases tolerance to myocardial ischemia/reperfusion (I/R). Experiments were conducted using a r
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 157(2)
Objective The aim of the study was to examine whether the cannabinoid agonist WIN55212-2 could attenuate ischemic spinal cord injury (SCI) in rats through inhibition of GAPDH/Siah1 signaling. Methods Male Sprague-Dawley rats were distributed randomly
Publikováno v:
BioMed Research International, Vol 2018 (2018)
BioMed Research International
BioMed Research International
Objectives. Protein arginine methyltransferase 2 (PRMT2) protects against vascular injury-induced intimal hyperplasia; however, little is known about the role of PRMT2 in angiotensin II (Ang II)-induced VSMCs proliferation and inflammation. This rese
Autor:
Fuli Yao, Jing Li, Xiaofang Zhao, Yong Wang, Ying Cheng, Chunyan Duan, Chunhong Feng, Xianming Xia, Rongyang Dai, Guosong Luo, Wenjing Yu, Mei Wei, Hong Zhou, Bin Xiao
Publikováno v:
Molecular medicine reports. 18(2)
Although activating transcription factor 4 (ATF4) is involved in the regulation of numerous biological functions, whether ATF4 has a direct role in liver injury is unknown. The aim of the present study was to investigate the role of ATF4 in liver inj
Autor:
Pei Juan Lu, Xiao Xiao, Chunping Qiao, Lei Xu, Qi Long Lu, Chi Hsien Wang, Derek J. Blake, Bin Xiao, Elizabeth Keramaris
Publikováno v:
Molecular Therapy. 21(10):1832-1840
Mutations in the FKRP gene are associated with a wide range of muscular dystrophies from mild limb-girdle muscular dystrophy (LGMD) 2I to severe Walker–Warburg syndrome and muscle-eye-brain disease. The characteristic biochemical feature of these d
Autor:
Xiao Xiao, Bin Xiao, H Yan, Chunping Qiao, G F Shen, Dao Wen Wang, Jiangang Jiang, Jianbin Li
Publikováno v:
Gene therapy. 24(3)
Inhibition of myostatin, a negative growth modulator for muscle, can functionally enhance muscle mass and improve glucose and fat metabolism in myostatin propeptide (MPRO) transgenic mice. This study was to investigate whether myostatin inhibition by
Autor:
Elizabeth Keramaris-Vrantsis, Hsin I. Ma, Chunping Qiao, Juan Li, Chi Hsien Wang, Hui Zheng, Jiangang Jiang, Ruhang Tang, Peijuan Lu, Yiumo Michael Chan, Qilong Lu, Bin Xiao, Xiao Xiao
Publikováno v:
The American Journal of Pathology. 178:261-272
Limb-girdle muscular dystrophy 2I (LGMD2I) is caused by mutations in the fukutin-related protein (FKRP) gene. Unlike its severe allelic forms, LGMD2I usually involves slower onset and milder course without defects in the central nervous system. The l
Autor:
Guangyong Li, Yuechao Wang, Zaili Dong, Wei Jing Zhang, Xiu Bin Xiao, Mi Li, Lianqing Liu, Ning Xi
Publikováno v:
Science China Life Sciences. 53:1189-1195
Elucidating the underlying mechanisms of cell physiology is currently an important research topic in life sciences. Atomic force microscopy methods can be used to investigate these molecular mechanisms. In this study, single-molecule force spectrosco
Autor:
Cheng Luo, Xi-Long Ou, Guo-Xian Ding, Yuan Zhang, Qin-Shi Zhao, Ye Yang, Guo-Sheng Chen, Yi-Ping Xue, Yun Shao, Wei-Hao Sun, Hai-Chen Xu, Bin Xiao, Su-Ming Zhou
Publikováno v:
Cancer Letters. 275:247-255
Although inhibition of cyclooxygenase-2 (COX-2) or activation of peroxisome proliferators-activated receptor gamma (PPAR-gamma) leads to growth inhibition in malignancies, the synergistic anti-tumor effects of combination of COX-2 inhibitor (NS-398)