Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Bin Xiao"'
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss, Pp 122-132 (2021)
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss, Pp 122-132 (2021)
Most recombinant adeno-associated virus (AAV) capsids utilized in liver gene therapy have significant levels of pre-existing neutralizing antibodies in the human population. These neutralizing factors limit the patient pools eligible for receiving AA
Autor:
Jian-Ying Chen, Sheng-Zhi Jiang, Xia Guo, Qiao Li, Jie-Rou Huang, Hui Rao, Li-Hua Zhang, Bin Xiao
Publikováno v:
Autoimmunity. 54(7)
The dysregulated microRNAs (miRNAs) are implicated in the malignancy of lupus nephritis (LN). This work aims to analyse the effect and mechanism of miR-146b-5p in lipopolysaccharides (LPS)-induced model of LN in vitro. The serum samples of LN patient
Publikováno v:
Cell Death and Disease, Vol 9, Iss 5, Pp 1-14 (2018)
Cell Death & Disease
Cell Death & Disease
Focal segmental glomerulosclerosis (FSGS) is a frequent glomerular disease, and is the common cause of nephrotic syndrome. However, there is no validated diagnostic blood biomarker for FSGS. Here, we performed a real-time PCR-based high-throughput mi
Autor:
Ming Li, Bin Xiao, Wenbo Hao, Haijian He, Chen Yu, Shuhong Luo, Huiqin Chen, Daxiang Chen, Daoyuan Gong, Zhenzhan Kuang, Ying-Song Wu, Yufeng Xiong, Daniel L. Rock, Mingjian Long, Fang Liu, Yong Wang
Publikováno v:
Oncotarget
Orf virus has been utilized as a safe and efficient viral vector against not only diverse infectious diseases, but also against tumors. However, the nature of the genes triggered by the vector in human cells is poorly characterized. Using RNA sequenc
Autor:
Xiao-ling Zhu, Xin Chen, Yu-Yuan Min, Yu Wang, Xu Li, Bin-Xiao Su, Wei Wang, Jia Huo, Jian-Ming Pei
Publikováno v:
Brain Research. 1659:113-120
Paraplegia caused by spinal cord ischemia is a severe complication following surgeries in the thoracic aneurysm. HMGB1 has been recognized as a key mediator in spinal inflammatory response after spinal cord injury. Electroacupuncture (EA) pretreatmen
The percentage of MDSC population in peripheral blood is significantly increased in lung cancer patients. The accumulation of MDSC contributes to the development of a tumour-associated immune suppressive environment. But the mechanism mediating MDSC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc54a852dee29ad06f2ad498e573923
Publikováno v:
Skeletal Muscle
Skeletal Muscle, Vol 9, Iss 1, Pp 1-16 (2019)
Skeletal Muscle, Vol 9, Iss 1, Pp 1-16 (2019)
Background Growth differentiation factor 11 (GDF11) is a member of the transforming growth factor β superfamily. The GDF11 propeptide, which is derived from the GDF11 precursor protein, blocks the activity of GDF11 and its homolog, myostatin, which
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 157(2)
Objective The aim of the study was to examine whether the cannabinoid agonist WIN55212-2 could attenuate ischemic spinal cord injury (SCI) in rats through inhibition of GAPDH/Siah1 signaling. Methods Male Sprague-Dawley rats were distributed randomly
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
To study the relationship between chromatin condensation, gene transcription and developmental competence during oocyte maturation and to explore the mechanisms by which meiotic arrest maintenance (MAM) and sexual maturity improve oocyte competence,
Autor:
Pei Juan Lu, Xiao Xiao, Chunping Qiao, Lei Xu, Qi Long Lu, Chi Hsien Wang, Derek J. Blake, Bin Xiao, Elizabeth Keramaris
Publikováno v:
Molecular Therapy. 21(10):1832-1840
Mutations in the FKRP gene are associated with a wide range of muscular dystrophies from mild limb-girdle muscular dystrophy (LGMD) 2I to severe Walker–Warburg syndrome and muscle-eye-brain disease. The characteristic biochemical feature of these d