Zobrazeno 1 - 10
of 44
pro vyhledávání: '"ZHAO LI"'
Publikováno v:
Pharmacological Reports. 73:858-867
Sodium-dependent glucose co-transporter 2 (SGLT2) inhibitor empagliflozin and glucagon-like peptide-1 (GLP-1) receptor agonist liraglutide are characterized as having cardiovascular benefits in patients with type 2 diabetes (T2D). Little is known reg
Autor:
Ze Tao, Tianshan She, Yanru Feng, Shisheng Wang, Heng Li, Xiaofeng Lu, Yan Liang, Zhao Li, Jingqiu Cheng, Hao Yang, Jie Chen, Qiuxiao Shi
Publikováno v:
Theranostics
Chemotherapeutic multidrug resistance (MDR) is the major hindrance for clinical therapy of colorectal cancer (CRC). Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) with selective cytotoxicity might overcome MDR of CRC cells. Unfortuna
Autor:
Si-Qi Dong, Lian-Jing Cao, Tong-Min Wang, Pei-Fen Zhang, Wen-Qiong Xue, Jing-Wen Huang, Yong-Qiao He, Zi-Yi Wu, Xiao-Hui Zheng, Xi-Zhao Li, Wei Hua Jia, Da-Wei Yang, Jiang-Bo Zhang
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose Capecitabine is an extensively used oral prodrug of 5-fluorouracil in treatment of colon cancer and is known to cause hand-foot syndrome (HFS). As the target enzyme for capecitabine, thymidylate synthase (TYMS) plays a key role for 5-fluorour
Autor:
Changkun Zhang, Yang Wang, Qian Cheng, Xiao Xiang, Shi-Hua Hu, Siqi Wang, Zhao Li, Jiye Zhu, Xiaodong Xun
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-15 (2020)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background The mechanism underlying sorafenib resistance in hepatocellular carcinoma (HCC) remains unclear. Accumulating evidence suggests that tumor-initiating cells (TICs) are a pivotal driving force. Both CD44 and Hedgehog signaling play crucial r
Autor:
Yiduo Sun, Yiyangzi Ma, Feng Gao, Ruru Guo, Lun He, Haitao Niu, Xin Li, Liangjing Lu, Gregg J. Silverman, Guobing Chen, Qiang Wei, Zhao Li, Mengtao Li, Jiali Yuan
Publikováno v:
Clinical Immunology. 233:108892
Background The etiology of systemic lupus erythematosus (SLE) is multifactorial. Recently, growing evidence suggests that the microbiota plays a role in SLE, yet whether gut microbiota participates in the development of SLE remains largely unknown. T
Autor:
Xiao Xiang, Yang Wang, Jinghang Guo, Xiaodong Xun, Qian Cheng, Siqi Wang, Zhao Li, Changkun Zhang, Jiye Zhu, Shi-Hua Hu
Publikováno v:
Journal of Immunotherapy (Hagerstown, Md. : 1997)
Supplemental Digital Content is available in the text.
The efficacy of adoptive cellular immunotherapy against cancer cells is limited due to the presence of immunosuppressive cells within the solid tumor microenvironment. The upregulation of ce
The efficacy of adoptive cellular immunotherapy against cancer cells is limited due to the presence of immunosuppressive cells within the solid tumor microenvironment. The upregulation of ce
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2020 (2020)
BioMed Research International, Vol 2020 (2020)
Purpose. Mycosis fungoides (MF) is the most common T-cell lymphoma, with indolent biologic behavior in the early stage and features of invasive in the tumor stage. The diagnosis of MF is still ambiguous and difficult. We focused on the proteomic prof
Autor:
Qingning Duan, Yingji Jin, Ying Dai, Jiebin Chen, Jun-Zhao Li, XueMei Sun, Qiu-Xiang Huang, LuLu Qian
Publikováno v:
International Immunopharmacology. 96:107712
Inflammation is a basal host defense response that eliminates the causes and consequences of infection and tissue injury. Macrophages are the primary immune cells involved in the inflammatory response. When activated by LPS, macrophages release vario
Publikováno v:
Clinical and Experimental Hypertension. 39:562-569
No consensus view has been published on the relationship between the aldosterone synthase gene (CYP11B2) -344C/T polymorphism and left ventricular hypertrophy (LVH) in Chinese Han. We undertook a meta-analysis to investigate the potential association
Publikováno v:
Theranostics
FKBP3 is a member of FK506-binding proteins (FKBPs). Little is known about the expression and functional role(s) of FKBP3 in non-small cell lung cancer (NSCLC). In the present study, we demonstrated up-regulation of FKBP3 expression, both at mRNA and