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Autor:
Minwoo Jeon, Han-Byul Lee, Seongju Jeong, Shin Hwang, Hyung-Don Kim, Zhengyi Wang, Hyunjoo Kim, Su-Hyung Park, Eun-Sil Sung, Jung Uijung, Jeon Jaehyoung, Eui-Cheol Shin, Yangmi Lim, Shinai Lee, Jiang Wenqing, Kim Youngkwang, Eunyoung Park, Youngeun Hong, Fang Lei, Son Yonggyu, Jonghwa Won, Jaeho Jung
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundStimulation of 4-1BB with agonistic antibodies is a promising strategy for improving the therapeutic efficacy of immune checkpoint inhibitors (ICIs) or for overcoming resistance to ICIs. However, dose-dependent hepatotoxicity was observed i