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Autor:
Hiroyuki Motoyama, Norifumi Kawada, Kohei Kotani, Akihiro Tamori, Naoshi Odagiri, Hideki Fujii, Hoang Hai, Le Thi Thanh Thuy, Atsushi Hagihara, Minh Phuong Dong, Masaru Enomoto, Ritsuzo Kozuka, Etsushi Kawamura, Sawako Uchida-Kobayashi, Kanako Yoshida
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Scientific Reports
Scientific Reports
Soluble immune checkpoint molecules are emerging novel mediators of immune regulation. However, it is unclear whether soluble immune checkpoint proteins affect the development of hepatocellular carcinoma (HCC) during nucleos(t)ide analogue (NA) treat
Autor:
Alceu de Oliveira Toledo Júnior, José Carlos Rebuglio Vellosa, Fábio André dos Santos, Fabiana Postiglioni Mansani, Rômulo Lopes da Costa, Sabrina Grassiolli, Lorena de Freitas Calixto, Bruno Queiroz Zardo, Felício de Freitas Netto, Elisangela Gueiber Montes, Marcelo Derbli Schafranski
Publikováno v:
Inflammopharmacology. 29:1819-1827
Background: Rheumatoid arthritis is an inflammatory disease with joint manifestations. In the presence of extra-articular manifestations, the morbidity and severity of the disease increases. Glucocorticoid is used as a treatment and may result in sid
Autor:
Marcella de Amorim Ferreira, Geisson Marcos Nardi, Thiele Osvaldt Rosales, Jamil Assreuy, Verônica Vargas Horewicz
Publikováno v:
Clinical Science. 135:2341-2356
Renal vascular reactivity to vasoconstrictors is preserved in sepsis in opposition to what happens in the systemic circulation. We studied whether this distinct behavior was related to α1 adrenergic receptor density, G protein-coupled receptor kinas
Autor:
Gere Sunder-Plassmann, Michaela Gabriel, Andreas Gleiss, Walter H. Hörl, Matthias Lorenz, Thomas Prikoszovich, Bernhard Bielesz, Rossella Monteforte, Michael Wolzt
Publikováno v:
Clin J Am Soc Nephrol
Background and objectives Whether iron supplementation in patients on hemodialysis could be delivered by less frequent but higher single doses compared with the currently more common higher-frequency schedules of lower single iron doses is unknown. D
Autor:
Thomas Christian Bonne, Tomas Ganz, Grace Jung, Andreas Breenfeldt Andersen, Elizabeta Nemeth, Nikolai Baastrup Nordsborg, Jesús R. Huertas, Jacob Bejder, Niels Vidiendal Olsen
Publikováno v:
Breenfeldt Andersen, A, Bonne, T C, Bejder, J, Jung, G, Ganz, T, Nemeth, E, Olsen, N V, Rodriguez Huertas, J & Nordsborg, N B 2021, ' Effects of altitude and recombinant human erythropoietin on iron metabolism: a randomized controlled trial ', American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, vol. 321, no. 2, pp. R152-R161 . https://doi.org/10.1152/ajpregu.00070.2021
Am J Physiol Regul Integr Comp Physiol
Am J Physiol Regul Integr Comp Physiol
Current markers of iron deficiency (ID) such as ferritin and hemoglobin have shortcomings, and hepcidin and erythroferrone (ERFE) could be of clinical relevance in relation to early assessment of ID. Here, we evaluate whether exposure to altitude-ind
Autor:
Yuhki Sakuraoka, Yukihiro Iso, Keiichi Kubota, Takamune Yamaguchi, Shozo Mori, Takayuki Shimizu, Kyung Hwa Park, Takatsugu Matsumoto, Taku Aoki, Takayuki Shiraki
Publikováno v:
Pancreas. 50:744-750
Although neoadjuvant chemotherapy (NAC)-gemcitabine plus S-1 (GS) has been reported to have a survival benefit in patients with resectable pancreatic ductal adenocarcinoma (PDAC), optimal candidates for NAC-GS have not been clearly identified.A total
Publikováno v:
Nutrition, Metabolism and Cardiovascular Diseases. 31:1276-1285
Background and aims Dual antiplatelet therapy (DAPT) and Renin-angiotensin system inhibitors (RASi) represent the cornerstone in the treatment of patients undergoing percutaneous coronary interventions (PCI), mainly after an acute ischemic event. How
Autor:
Özlem Erten, Sadiman Kiykac Altinbas, Omer Lutfi Tapisiz, Gülçin Güler Şimşek, Salim Erkaya, Yıldız Akdaş Reis, Ümit Göktolga
Publikováno v:
Reproductive Sciences. 28:2650-2660
Postoperative adhesions can cause serious complications, including intestinal obstruction, chronic abdominopelvic pain, and infertility in women. Here we investigate the effects of disulfiram on the postoperative adhesion model. Female Wistar rats we
Autor:
Areti Pagiantza, Ioannis Farmakis, Stefanos Zafeiropoulos, Ioannis Doundoulakis, Haralambos Karvounis, George Giannakoulas, Christina Antza
Publikováno v:
Journal of Cardiovascular Pharmacology. 77:397-407
Lipoprotein(a) [Lp(a)] is a cardiovascular factor, for which there is no approved specific lowering treatment. Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors have been shown to have lowering effects on Lp(a). Aim of this systematic
Publikováno v:
Breast Cancer. 28:630-643
The optimal duration of endocrine therapy for patients with hormone receptor-positive (HR-positive) breast cancer is still unclear. This meta-analysis aims to determine the optimal duration of endocrine therapy with extended aromatase inhibitors (AI)