Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Bin Xiao"'
Autor:
Dan-Dan Li, Dong-Hao Bai, Jee H. Jung, Bin Xiao, Ying Wang, Na Zhao, Shang-Wu Jin, Li-Dong Sun, Eun La Kim
Publikováno v:
Biomolecules & Therapeutics
In a search for effective PPAR-γ agonists, 110 clinical drugs were screened via molecular docking, and 9 drugs, including parecoxib, were selected for subsequent biological evaluation. Molecular docking of parecoxib to the ligand-binding domain of P
Autor:
Xijun Wang, Hong-Bin Xiao, Ai-Xia Ju, Yong Hu, Jiao Zhao, Guang Xu, Qing-Song Qie, Qiu-Hong Li
Publikováno v:
World Journal of Traditional Chinese Medicine, Vol 7, Iss 3, Pp 332-338 (2021)
Objective: To explore the mechanism underlying the effect of Panax notoginseng saponins (PNS) on the pharmacokinetics of nifedipine (NF) in rats. Materials and Methods: Twenty-four rats were randomly divided into blank (BL) group, PNS group, NF group
Autor:
Jian-Ying Chen, Sheng-Zhi Jiang, Xia Guo, Qiao Li, Jie-Rou Huang, Hui Rao, Li-Hua Zhang, Bin Xiao
Publikováno v:
Autoimmunity. 54(7)
The dysregulated microRNAs (miRNAs) are implicated in the malignancy of lupus nephritis (LN). This work aims to analyse the effect and mechanism of miR-146b-5p in lipopolysaccharides (LPS)-induced model of LN in vitro. The serum samples of LN patient
Publikováno v:
Processes, Vol 9, Iss 1244, p 1244 (2021)
Processes
Volume 9
Issue 7
Processes
Volume 9
Issue 7
In this study, changes in hydrophobic interactions among gluten proteins were analyzed during dough mixing. Size-exclusion high-performance chromatography and two-dimensional fluorescence difference gel electrophoresis were performed on proteins extr
Autor:
Ke-Yu Chen, Xiao-Ming Zhang, Pan Li, Zhu Jiang, Zhi-Yang Xia, Chengyi Shen, Qian Xia, Tao Cheng, Chunrong Zhu, Lei Zhong, Bin Xiao, Changqiang Wu
Publikováno v:
Journal of medicinal chemistry. 64(13)
Liver-specific contrast agents (CAs) can improve the Magnetic resonance imaging (MRI) detection of focal and diffuse liver lesions by increasing the lesion-to-liver contrast. A novel Mn(II) complex, Mn-BnO-TyrEDTA, with a lipophilic group-modified et
Autor:
Yongjun Zhang, Jingjing Tan, Qiqi Huang, Jiangying Zeng, Ge Wang, Shuang Chen, Bin Xiao, jing yao, Tao Feng
Publikováno v:
International journal of biological macromolecules. 187
An efficient extraction method of Auricularia auricula polysaccharides (AAPs) by neutral protease was developed and optimized by response surface methodology. AAPs were graded by stepwise ethanol precipitation, the fraction with high recovery rate an
Autor:
Yutao Chen, Ge Wang, Zhiyu Fang, Bin Xiao, Jingyi Gu, Meng Shen, Jia Li, Tao Feng, Yongjun Zhang, Weimin Wang
Publikováno v:
Food & Function. 10:5531-5543
Caenorhabditis elegans is an important model organism for studying stress response mechanisms and identifying genetic pathways that influence longevity. The present study was designed to explore the in vivo-antioxidant potential and the probable mech
Autor:
Shuxin Shen, Yun-bin Xiao, Zonglei Zhao, Hairui Li, Feng Liu, Jianping Bin, Yan Wang, Ye Yuan, Chuanxi Zhang, Nvqin He, Ying Li, Shengcun Guo, Wangjun Liao, Yulin Liao, Junfen Wang, Yanmei Chen, Yongkang Lu
Publikováno v:
Biomaterials. 181:293-306
With the rapid development of cancer-targeted nanotechnology, a variety of nanoparticle-based drug delivery systems have clinically been employed in cancer therapy. However, multidrug resistance significantly impacts the therapeutic efficacy. Physica
Publikováno v:
Neuroreport. 31(18)
The role of norepinephrine of the hippocampal dentate gyrus in spatial learning and memory alteration induced by chronic restraint stress (CRS, 3 h/day, 6 weeks) was investigated in aged rats. Spatial learning and memory were assessed by the Morris w
Autor:
Xijing Zhang, Dandan Cheng, Jiajia Wang, Haixing Zhong, Zhenhua Jiang, Zongping Fang, Ting Gu, Wugang Hou, Bin-Xiao Su, Yi Li, Haiyun Guo, Shiquan Wang
Publikováno v:
Brain research. 1757
Rosmarinic acid (RA), a natural polyphenol, possesses potent antioxidant and anti-inflammatory activities. To evaluate the ability of RA to cure ischemic stroke and post-stroke depression (PSD), rats were treated with various doses of RA after cerebr