Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Bin Xiao"'
Autor:
Shuxin Shen, Yun-bin Xiao, Zonglei Zhao, Hairui Li, Feng Liu, Jianping Bin, Yan Wang, Ye Yuan, Chuanxi Zhang, Nvqin He, Ying Li, Shengcun Guo, Wangjun Liao, Yulin Liao, Junfen Wang, Yanmei Chen, Yongkang Lu
Publikováno v:
Biomaterials. 181:293-306
With the rapid development of cancer-targeted nanotechnology, a variety of nanoparticle-based drug delivery systems have clinically been employed in cancer therapy. However, multidrug resistance significantly impacts the therapeutic efficacy. Physica
Autor:
Shuwen Liu, Juan Li, Bin Xiao, Wei Zhang, Lijie Song, Chuanhong Yang, Jie Wang, Linhai Li, Xiaomei Kou, Li Wang, Yan Wang
Publikováno v:
Cancer Science
The underlying mechanisms of breast cancer cells metastasizing to distant sites are complex and multifactorial. Bone sialoprotein (BSP) and αvβ3 integrin were reported to promote the metastatic progress of breast cancer cells, particularly metastas
Autor:
Yongyin He, Jingrun Lu, Jing Qu, Weiwei Li, Jianfeng Hang, Wenbo Hao, Zhenzhan Kuang, Zhaohui Sun, Ting Lei, Chun Deng, Weiyun Zhang, Bin Xiao, Linhai Li, Lidan Chen, Quan Zhou
Publikováno v:
Molecular Carcinogenesis
Glutamate Ionotropic Receptor Kainate Type Subunit 3 (GRIK3) is an important excitatory neurotransmitter receptor that plays a significant role in various neurodegenerative diseases. However, the biological functions of GRIK3 in malignancies are larg
Autor:
Yang Jie, Hai Jiang, Lijun Zhao, Chunyu Wang, Dong Xiaolin, Guihua Qiu, Bo Yang, Bin Xiao, Dongling Hu
Publikováno v:
Biomedicine & Pharmacotherapy. 72:125-134
Oridonin, a bioactive diterpenoid isolated from Rabdosia rubescens, has been found to exhibit various anti-tumor effects. In this work, to investigate its pharmacological effects on human colorectal carcinoma HCT-116 and LoVo cells, cell proliferatio
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 10, p e0164105 (2016)
PLoS ONE, Vol 11, Iss 10, p e0164105 (2016)
Increasing evidence has indicated that many microRNAs participate in the development and progression of esophageal cancer and gene expression regulation. MicroRNA-20b (miR-20b) has been reported to be aberrantly expressed in various cancers, but its
Autor:
Elizabeth Keramaris-Vrantsis, Hsin I. Ma, Chunping Qiao, Juan Li, Chi Hsien Wang, Hui Zheng, Jiangang Jiang, Ruhang Tang, Peijuan Lu, Yiumo Michael Chan, Qilong Lu, Bin Xiao, Xiao Xiao
Publikováno v:
The American Journal of Pathology. 178:261-272
Limb-girdle muscular dystrophy 2I (LGMD2I) is caused by mutations in the fukutin-related protein (FKRP) gene. Unlike its severe allelic forms, LGMD2I usually involves slower onset and milder course without defects in the central nervous system. The l
Publikováno v:
Chinese Journal of Cancer. 29:741-746
BACKGROUND AND OBJECTIVE Rosiglitazone is a peroxisome proliferators-activated receptor gamma (PPARgamma) ligand, which inhibits tumor growth by activating PPARgamma signaling pathways. Fluorouracil (5-FU) is one of the commonly used chemotherapeutic
Autor:
Christina L. Addison, James Villeneuve, Khalid N. Al-Zahrani, Grant A. Howe, Mohamed Shaad Hasim, Bin Xiao, Luc A. Sabourin, Glenwood D. Goss, Huijun Zhao, Harmanjatinder S. Sekhon, Jim Dimitroulakos
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0150567 (2016)
PLoS ONE, Vol 11, Iss 3, p e0150567 (2016)
Blockade of epidermal growth factor receptor (EGFR) activity has been a primary therapeutic target for non-small cell lung cancers (NSCLC). As patients with wild-type EGFR have demonstrated only modest benefit from EGFR tyrosine kinase inhibitors (TK
Autor:
Jia-xin Min, Yin-bin Xiao, Pin Qian, Zubin Yu, Li Bai, Guisheng Qian, Guansong Wang, Chunxue Bai
Publikováno v:
Cell biology international. 33(9)
SOCS3 is regarded as a major negative regulator of STAT3. Recent evidence indicates that SOCS3 regulates strength and duration of other signaling pathways including ras/ERK1/2/MAPK, PI3-K/Akt in non-malignant cells. The repression or silence of SOCS3